ADAMTS1 Protein for Human(Homo sapiens) | EIAab.comADAMTS1 Protein for Human(Homo sapiens)

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Index > Protein center > ADAMTS1(Gene name) > Human

ADAMTS1 (Gene name),

A disintegrin and metalloproteinase with thrombospondin motifs 1 (Protein name ), ATS1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ADAMTS1(KIAA1346;METH1);

Protein name:

A disintegrin and metalloproteinase with thrombospondin motifs 1(ADAM-TS 1;ADAM-TS1;ADAMTS-1);

Alternative:

METH-1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Function:

Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

967

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

967:

LKKPKHFIDF | CTMAECS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:9510

STRING:

9606.ENSP00000284984

MIM:

605174

SMR:

Q9UHI8

Pfam:

PF05986

UniGene:

Hs.643357

String:

Q9UHI8

Uniprot:

Q9UHI8

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ELISA Kit for Human ADAM-TS 1

Cat.:

E1973h

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MSDS:

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Packing:

96T

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ELISA Kit for Human ADAM-TS 1

Cat.:

E1973m

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96T

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ELISA Kit for Human ADAM-TS 1

Cat.:

E1973r

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MSDS:

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Packing:

96T

CLIA Kit for Human ADAM-TS 1

Cat.:

U1973h

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Packing:

96T

CLIA Kit for Human ADAM-TS 1

Cat.:

U1973r

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Packing:

96T

CLIA Kit for Human ADAM-TS 1

Cat.:

U1973m

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Packing:

96T

Polyclonal Antibody for Human ADAM-TS 1

Cat.:

P1973Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ADAM-TS 1

Cat.:

P1973Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ADAM-TS 1

Cat.:

P1973Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human ADAM-TS 1

Protein for Human ADAM-TS 1

Cat.:

R1973h

Price:

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Packing:

1mg

Purity:

>90%

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Cloning, characterization and mapping on human chromosome 21 of the orthologue of murine Adamts-1."
Casas C. , Pritchard M.A. , Estivill X. , Arbones M.L.
Submitted (1999-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PRO-227
2.

"METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity."
Vazquez F. , Hastings G. , Ortega M.-A. , Lane T.F. , Oikemus S. , Lombardo M. , Iruela-Arispe M.L.
J. Biol. Chem.274:23349-23357(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PRO-227;FUNCTION
tissue: Heart.
3.

"Differential gene expression by endothelial cells in distinct angiogenic states."
Glienke J. , Schmitt A.O. , Pilarsky C. , Hinzmann B. , Weiss B. , Rosenthal A. , Thierauch K.H.
Eur. J. Biochem.267:2820-2830(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PRO-227
tissue: Endothelial cell.
4.

"Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
Nagase T. , Kikuno R. , Ishikawa K. , Hirosawa M. , Ohara O.
DNA Res.7:65-73(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
5.

"The DNA sequence of human chromosome 21."
Hattori M. , Fujiyama A. , Taylor T.D. , Watanabe H. , Yada T. , Park H.-S. , Toyoda A. , Ishii K. , Totoki Y. , Choi D.-K. , Groner Y. , Soeda E. , Ohki M. , Takagi T. , Sakaki Y. , Taudien S. , Blechschmidt K. , Polley A. , more...
Nature405:311-319(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 418-967
tissue: Melanoma.
8.

"Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains."
Gerhardt S. , Hassall G. , Hawtin P. , McCall E. , Flavell L. , Minshull C. , Hargreaves D. , Ting A. , Pauptit R.A. , Parker A.E. , Abbott W.M.
J. Mol. Biol.373:891-902(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 253-548 ALONE AND IN COMPLEX WITH INHIBITOR;ACTIVE SITE;COFACTOR;ZINC-BINDING SITES;CALCIUM-BINDING SITES;DISULFIDE BONDS

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