Protein name:
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor;BMPR-2) ;
Alternative:
Bone morphogenetic protein receptor type II (BMP type II receptor;BMPR-II) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MTSSLQRPWR | VPWLPWTILL | VSTAAASQNQ | ERLCAFKDPY | QQDLGIGESR |
100:
ISHENGTILC | SKGSTCYGLW | EKSKGDINLV | KQGCWSHIGD | PQECHYEECV |
150:
VTTTPPSIQN | GTYRFCCCST | DLCNVNFTEN | FPPPDTTPLS | PPHSFNRDET |
200:
IIIALASVSV | LAVLIVALCF | GYRMLTGDRK | QGLHSMNMME | AAASEPSLDL |
250:
DNLKLLELIG | RGRYGAVYKG | SLDERPVAVK | VFSFANRQNF | INEKNIYRVP |
300:
LMEHDNIARF | IVGDERVTAD | GRMEYLLVME | YYPNGSLCKY | LSLHTSDWVS |
350:
SCRLAHSVTR | GLAYLHTELP | RGDHYKPAIS | HRDLNSRNVL | VKNDGTCVIS |
400:
DFGLSMRLTG | NRLVRPGEED | NAAISEVGTI | RYMAPEVLEG | AVNLRDCESA |
450:
LKQVDMYALG | LIYWEIFMRC | TDLFPGESVP | EYQMAFQTEV | GNHPTFEDMQ |
500:
VLVSREKQRP | KFPEAWKENS | LAVRSLKETI | EDCWDQDAEA | RLTAQCAEER |
550:
MAELMMIWER | NKSVSPTVNP | MSTAMQNERN | LSHNRRVPKI | GPYPDYSSSS |
600:
YIEDSIHHTD | SIVKNISSEH | SMSSTPLTIG | EKNRNSINYE | RQQAQARIPS |
650:
PETSVTSLST | NTTTTNTTGL | TPSTGMTTIS | EMPYPDETNL | HTTNVAQSIG |
700:
PTPVCLQLTE | EDLETNKLDP | KEVDKNLKES | SDENLMEHSL | KQFSGPDPLS |
750:
STSSSLLYPL | IKLAVEATGQ | QDFTQTANGQ | ACLIPDVLPT | QIYPLPKQQN |
800:
LPKRPTSLPL | NTKNSTKEPR | LKFGSKHKSN | LKQVETGVAK | MNTINAAEPH |
850:
VVTVTMNGVA | GRNHSVNSHA | ATTQYANGTV | LSGQTTNIVT | HRAQEMLQNQ |
900:
FIGEDTRLNI | NSSPDEHEPL | LRREQQAGHD | EGVLDRLVDR | RERPLEGGRT |
950:
NSNNNNSNPC | SEQDVLAQGV | PSTAADPGPS | KPRRAQRPNS | LDLSATNVLD |
1000:
GSSIQIGEST | QDGKSGSGEK | IKKRVKTPYS | LKRWRPSTWV | ISTESLDCEV |
1038:
NNNGSNRAVH | SKSSTAVYLA | EGGTATTMVS | KDIGMNCL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human BMP type-2 receptor
ELISA Kit for Human BMP type-2 receptor
CLIA Kit for Human BMP type-2 receptor
CLIA Kit for Human BMP type-2 receptor
Polyclonal Antibody for Human BMP type-2 receptor
Polyclonal Antibody for Human BMP type-2 receptor
Monoclonal Antibody for Human BMP type-2 receptor
Monoclonal Antibody for Human BMP type-2 receptor
Protein for Human BMP type-2 receptor
Protein for Human BMP type-2 receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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