FGF1 Protein for Human(Homo sapiens) | EIAab.comFGF1 Protein for Human(Homo sapiens)

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Index > Protein center > FGF1(Gene name) > Human

FGF1 (Gene name),

Heparin-binding growth factor 1 (Protein name ), FGF1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

FGF1(FGFA);

Protein name:

Heparin-binding growth factor 1(HBGF-1);

Alternative:

Beta-endothelial cell growth factor(ECGF);Acidic fibroblast growth factor(aFGF);ECGF-beta(HBGF-1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP1. Part of a Cu(2+)-dependent multiprotein aggregate containing FGF1, S100A13 and SYT1. Interacts with SYT1 (By similarity). Interacts with S100A13.

Function:

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.

Subcellular Location:

Secreted Cytoplasm Cytoplasm cell cortex Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.

Protein Attributes:

Sequence length:

155

Sequence:

50:

100:

150:

155:

PVSSD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.483635

SMR:

P05230

MIM:

131220

String:

P05230

STRING:

9606.ENSP00000338548

Pfam:

PF00167

KEGG:

hsa:2246

Uniprot:

P05230

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ELISA Kit for Human HBGF-1

Cat.:

E0032h

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96T

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ELISA Kit for Human HBGF-1

Cat.:

E0032m

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96T

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ELISA Kit for Human HBGF-1

Cat.:

E0032r

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96T

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ELISA Kit for Human HBGF-1

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E0032p

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96T

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ELISA Kit for Human HBGF-1

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E0032b

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96T

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ELISA Kit for Human HBGF-1

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E0032d

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96T

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ELISA Kit for Human HBGF-1

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E0032c

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96T

CLIA Kit for Human HBGF-1

Cat.:

U0032r

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96T

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CLIA Kit for Human HBGF-1

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U0032p

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96T

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CLIA Kit for Human HBGF-1

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U0032m

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96T

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CLIA Kit for Human HBGF-1

Cat.:

U0032h

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96T

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CLIA Kit for Human HBGF-1

Cat.:

U0032d

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96T

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CLIA Kit for Human HBGF-1

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U0032b

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96T

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CLIA Kit for Human HBGF-1

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U0032c

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96T

Polyclonal Antibody for Human HBGF-1

Cat.:

P0032Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human HBGF-1

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P0032Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human HBGF-1

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P0032Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human HBGF-1

Monoclonal Antibody for Human HBGF-1

Protein for Human HBGF-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤4.7%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤6.8%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of FGF1 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	95	93-97
Plasma	97	96-102

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of FGF1 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-100%	97-104%	95-98%	91-96%
EDTA plasma(n=5)	89-93%	102-105%	94-97%	93-98%
heparin plasma(n=5)	91-95%	96-99%	106-108%	87-93%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization."
Jaye M. , Howk R. , Burgess W. , Ricca G.A. , Chiu I.-M. , Ravera M.W. , O'Brien S.J. , Modi W.S. , Maciag T. , Drohan W.N.
Science233:541-545(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain stem.
2.

"Structural analysis of the gene for human acidic fibroblast growth factor."
Mergia A. , Tischer E. , Graves D. , Tumolo A. , Miller J. , Gospodarowicz D. , Abraham J.A. , Shipley G.D. , Fiddes J.C.
Biochem. Biophys. Res. Commun.164:1121-1129(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Cloning of the gene coding for human class 1 heparin-binding growth factor and its expression in fetal tissues."
Wang W.P. , Lehtoma K. , Varban M.L. , Krishnan I. , Chiu I.M.
Mol. Cell. Biol.9:2387-2395(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Brain stem.
4.

"Alternative splicing generates two forms of mRNA coding for human heparin-binding growth factor 1."
Chiu I.M. , Wang W.P. , Lehtoma K.
Oncogene5:755-762(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain stem.
5.

"Cloning and sequence analysis of the human acidic fibroblast growth factor gene and its preservation in leukemia patients."
Wang W.P. , Quick D. , Balcerzak S.P. , Needleman S.W. , Chiu I.M.
Oncogene6:1521-1529(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"An acidic fibroblast growth factor protein generated by alternate splicing acts like an antagonist."
Li Y.L. , Kha H. , Golden J.A. , Migchielsen A.A.J. , Goetzl E.J. , Turck E.J.
J. Exp. Med.175:1073-1080(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
7.

"The expression of acidic fibroblast growth factor (heparin-binding growth factor-1) and cytokine genes in human cardiac allografts and T cells."
Zhao X.M. , Yeoh T.K. , Hiebert M. , Frist W.H. , Miller G.G.
Transplantation56:1177-1182(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [MRNA] OF 1-154 (ISOFORM 1);TISSUE SPECIFICITY
8.

NIEHS SNPs program
Submitted (2004-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLU-21
9.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Cerebellum.
10.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
12.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Liver.
13.

"The gene for human acidic fibroblast growth factor encodes two upstream exons alternatively spliced to the first coding exon."
Crumley G. , Dionne C.A. , Jaye M.
Biochem. Biophys. Res. Commun.171:7-13(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-40 (ISOFORMS 1/2)
14.

"Human class 1 heparin-binding growth factor: structure and homology to bovine acidic brain fibroblast growth factor."
Harper J.W. , Strydom D.J. , Lobb R.R.
Biochemistry25:4097-4103(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 16-155 (ISOFORM 1)
15.

"The complete amino acid sequence of human brain-derived acidic fibroblast growth factor."
Gimenez-Gallego G. , Conn G. , Hatcher V.B. , Thomas K.A.
Biochem. Biophys. Res. Commun.138:611-617(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 16-155 (ISOFORM 1)
16.

"Amino acid sequence of human acidic fibroblast growth factor."
Gautschi-Sova P. , Mueller T. , Boehlen P.
Biochem. Biophys. Res. Commun.140:874-880(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 16-155 (ISOFORM 1)
17.

"Human brain-derived acidic and basic fibroblast growth factors: amino terminal sequences and specific mitogenic activities."
Gimenez-Gallego G. , Conn G. , Hatcher V.B. , Thomas K.A.
Biochem. Biophys. Res. Commun.135:541-548(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 16-47 (ISOFORMS 1/2)
18.

"Partial molecular characterization of endothelial cell mitogens from human brain: acidic and basic fibroblast growth factors."
Gautschi P. , Frater-Schroeder M. , Boehlen P.
FEBS Lett.204:203-207(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 16-49 (ISOFORMS 1/2)
19.

"Characterization and molecular cloning of a putative binding protein for heparin-binding growth factors."
Wu D.Q. , Kan M.K. , Sato G.H. , Okamoto T. , Sato J.D.
J. Biol. Chem.266:16778-16785(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH FGFBP1 AND FGF2;INTERACTION WITH FGFBP1
20.

"Receptor specificity of the fibroblast growth factor family."
Ornitz D.M. , Xu J. , Colvin J.S. , McEwen D.G. , MacArthur C.A. , Coulier F. , Gao G. , Goldfarb M.
J. Biol. Chem.271:15292-15297(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGFR1; FGFR2; FGFR3 AND FGFR4;FUNCTION IN CELL PROLIFERATION
21.

"Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress."
Landriscina M. , Bagala C. , Mandinova A. , Soldi R. , Micucci I. , Bellum S. , Prudovsky I. , Maciag T.
J. Biol. Chem.276:25549-25557(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;COPPER-BINDING;INTERACTION WITH S100A13 AND SYT1
22.

"Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor."
Skjerpen C.S. , Wesche J. , Olsnes S.
J. Biol. Chem.277:23864-23871(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CSNK2A; CSNK2B; FGF2; FIBP AND LRRC59;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF SER-114; SER-131 AND LYS-133
23.

"Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family."
Zhang X. , Ibrahimi O.A. , Olsen S.K. , Umemori H. , Mohammadi M. , Ornitz D.M.
J. Biol. Chem.281:15694-15700(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGFR1; FGFR2; FGFR3 AND FGFR4;FUNCTION IN STIMULATION OF CELL PROLIFERATION
24.

"The release of fibroblast growth factor-1 from melanoma cells requires copper ions and is mediated by phosphatidylinositol 3-kinase/Akt intracellular signaling pathway."
Di Serio C. , Doria L. , Pellerito S. , Prudovsky I. , Micucci I. , Massi D. , Landriscina M. , Marchionni N. , Masotti G. , Tarantini F.
Cancer Lett.267:67-74(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
25.

"Effect of human S100A13 gene silencing on FGF-1 transportation in human endothelial cells."
Cao R. , Yan B. , Yang H. , Zu X. , Wen G. , Zhong J.
J. Formos. Med. Assoc.109:632-640(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
26.

"Cellular signaling by fibroblast growth factor receptors."
Eswarakumar V.P. , Lax I. , Schlessinger J.
Cytokine Growth Factor Rev.16:139-149(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
27.

"Fibroblast growth factor signalling: from development to cancer."
Turner N. , Grose R.
Nat. Rev. Cancer10:116-129(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
28.

"Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnalpha1 and Kpnbeta1."
Zhen Y. , Sorensen V. , Skjerpen C.S. , Haugsten E.M. , Jin Y. , Walchli S. , Olsnes S. , Wiedlocha A.
Traffic13:650-664(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PHOSPHORYLATION;MUTAGENESIS OF 24-LYS--LYS-27
29.

"Three-dimensional structures of acidic and basic fibroblast growth factors."
Zhu X. , Komiya H. , Chirino A. , Faham S. , Fox G.M. , Arakawa T. , Hsu B.T. , Rees D.C.
Science251:90-93(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 16-155
30.

"X-ray crystal structure of human acidic fibroblast growth factor."
Blaber M. , Disalvo J. , Thomas K.A.
Biochemistry35:2086-2094(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 21-155
31.

"Structure of a heparin-linked biologically active dimer of fibroblast growth factor."
DiGabriele A.D. , Lax I. , Chen D.I. , Svahn C.M. , Jaye M. , Schlessinger J. , Hendrickson W.A.
Nature393:812-817(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 21-155 IN COMPLEX WITH HEPARIN
32.

"Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity."
Plotnikov A.N. , Hubbard S.R. , Schlessinger J. , Mohammadi M.
Cell101:413-424(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 22-155 IN COMPLEX WITH FGFR1
33.

"Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin."
Pellegrini L. , Burke D.F. , von Delft F. , Mulloy B. , Blundell T.L.
Nature407:1029-1034(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 16-155 IN COMPLEX WITH FGFR2 AND HEPARIN
34.

"Structural interactions of fibroblast growth factor receptor with its ligands."
Stauber D.J. , DiGabriele A.D. , Hendrickson W.A.
Proc. Natl. Acad. Sci. U.S.A.97:49-54(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 21-155 IN COMPLEX WITH FGFR2
35.

"Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor."
Kim J. , Blaber S.I. , Blaber M.
Protein Sci.11:459-466(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 16-155
36.

"Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity."
Olsen S.K. , Ibrahimi O.A. , Raucci A. , Zhang F. , Eliseenkova A.V. , Yayon A. , Basilico C. , Linhardt R.J. , Schlessinger J. , Mohammadi M.
Proc. Natl. Acad. Sci. U.S.A.101:935-940(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) IN COMPLEX WITH FGFR3
37.

"1H-NMR assignment and solution structure of human acidic fibroblast growth factor activated by inositol hexasulfate."
Pineda-Lucena A. , Jimenez M.A. , Nieto J.L. , Santoro J. , Rico M. , Gimenez-Gallego G.
J. Mol. Biol.242:81-98(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 24-155 IN COMPLEX WITH INOSITOL HEXASULFATE;PROTEIN SEQUENCE OF 24-27
38.

"Three-dimensional structure of acidic fibroblast growth factor in solution: effects of binding to a heparin functional analog."
Pineda-Lucena A. , Jimenez M.A. , Lozano R.M. , Nieto J.L. , Santoro J. , Rico M. , Gimenez-Gallego G.
J. Mol. Biol.264:162-178(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 24-155
39.

"Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas."
Lozano R.M. , Jimenez M. , Santoro J. , Rico M. , Gimenez-Gallego G.
J. Mol. Biol.281:899-915(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 24-155
40.

"Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors."
Fernandez I.S. , Cuevas P. , Angulo J. , Lopez-Navajas P. , Canales-Mayordomo A. , Gonzalez-Corrochano R. , Lozano R.M. , Valverde S. , Jimenez-Barbero J. , Romero A. , Gimenez-Gallego G.
J. Biol. Chem.285:11714-11729(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS) OF 24-153 IN COMPLEX WITH GENTISIC ACID AND 2,5-DIHYDROXYPHENYLSULFONATE;FUNCTION;HEPARIN-BINDING;INTERACTION WITH WITH FGFR1
41.

"The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion."
Mohan S.K. , Rani S.G. , Yu C.
J. Biol. Chem.285:15464-15475(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 23-155

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