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Index > Protein center > Mmp17(Gene name) > Mouse
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  • Mmp17 (Gene name),
  • Matrix metalloproteinase-17 (Protein name ),  MMP17_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Mmp17(Mt4mmp);
    Protein name:
    Matrix metalloproteinase-17(MMP-17);
    Alternative:
    Membrane-type-4 matrix metalloproteinase(MT4-MMP;MT4MMP);Membrane-type matrix metalloproteinase 4(MT-MMP 4;MTMMP4);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor Extracellular side Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    578
    Sequence:
    50:
    MGRRPRGPGS | PRGPGPPRPG | PGLPPLLLVL | ALAAHGGCAA | PAPRAEDLSL | 
    100:
    GVEWLSRFGY | LPPADPASGQ | LQTQEELSKA | ITAMQQFGGL | ETTGILDEAT | 
    150:
    LALMKTPRCS | LPDLPPGAQS | RRKRQTPPPT | KWSKRNLSWR | VRTFPRDSPL | 
    200:
    GRDTVRALMY | YALKVWSDIT | PLNFHEVAGN | AADIQIDFSK | ADHNDGYPFD | 
    250:
    GPGGTVAHAF | FPGDHHTAGD | THFDDDEPWT | FRSSDAHGMD | LFAVAVHEFG | 
    300:
    HAIGLSHVAA | PSSIMQPYYQ | GPVGDPLRYG | LPYEDRVRVW | QLYGVRESVS | 
    350:
    PTAQLDTPEP | EEPPLLPEPP | NNRSSTPPQK | DVPHRCTAHF | DAVAQIRGEA | 
    400:
    FFFKGKYFWR | LTRDRHLVSL | QPAQMHRFWR | GLPLHLDSVD | AVYERTSDHK | 
    450:
    IVFFKGDRYW | VFKDNNVEEG | YPRPVSDFSL | PPGGIDAVFS | WAHNDRTYFF | 
    500:
    KDQLYWRYDD | HTRRMDPGYP | AQGPLWRGVP | SMLDDAMRWS | DGASYFFRGQ | 
    550:
    EYWKVLDGEL | EAAPGYPQST | ARDWLVCGEP | LADAEDVGPG | PQGRSGAQDG | 
    578:
    LAVCSCTSDA | HRLALPSLLL | LTPLLWGL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse MMP-17
    Cat.:
    E0554h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse MMP-17
    Cat.:
    E0554m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse MMP-17
    Cat.:
    U0554m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse MMP-17
    Cat.:
    U0554h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse MMP-17
    Cat.:
    P0554Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse MMP-17
    Cat.:
    P0554Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse MMP-17
    Monoclonal Antibody for Mouse MMP-17
    Protein for Mouse MMP-17
    Protein for Mouse MMP-17

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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts."
      Kajita M. , Kinoh H. , Ito N. , Takamura A. , Itoh Y. , Okada A. , Sato H. , Seiki M.
      FEBS Lett.457:353-356(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Embryonic brain.
    2. 2.
      Seiki M.
      Submitted (2002-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO C-TERMINUS
    3. 3.
      "Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2."
      English W.R. , Puente X.S. , Freije J.M.P. , Knaeuper V. , Amour A. , Merryweather A. , Lopez-Otin C. , Murphy G.
      J. Biol. Chem.275:14046-14055(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
      tissue: Brain.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Embryonic brain.
    6. 6.
      "Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase."
      Itoh Y. , Kajita M. , Kinoh H. , Mori H. , Okada A. , Seiki M.
      J. Biol. Chem.274:34260-34266(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR;MUTAGENESIS OF GLU-248
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