TNFRSF8 Protein for Human(Homo sapiens) | EIAab.comTNFRSF8 Protein for Human(Homo sapiens)

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TNFRSF8 (Gene name),

Tumor necrosis factor receptor superfamily member 8 (Protein name ), TNR8_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TNFRSF8(CD30;D1S166E);

Protein name:

Tumor necrosis factor receptor superfamily member 8;

Alternative:

Ki-1 antigen;CD30L receptor;Lymphocyte activation antigen CD30;

CD:

CD30;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.

Function:

Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.

Subcellular Location:

Isoform Short Cytoplasm

Protein Attributes:

Sequence length:

595

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

595:

ELEADHTPHY | PEQETEPPLG | SCSDVMLSVE | EEGKEDPLPT | AASGK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P28908

String:

P28908

KEGG:

hsa:943

MIM:

153243

UniGene:

Hs.1314

STRING:

9606.ENSP00000263932

Pfam:

PF00020

Uniprot:

P28908

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 8

Cat.:

E0020h

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96T

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 8

Cat.:

E0020m

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96T

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 8

Cat.:

E0020r

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96T

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CLIA Kit for Human Tumor necrosis factor receptor superfamily member 8

Cat.:

U0020m

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96T

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CLIA Kit for Human Tumor necrosis factor receptor superfamily member 8

Cat.:

U0020h

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96T

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CLIA Kit for Human Tumor necrosis factor receptor superfamily member 8

Cat.:

U0020r

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Packing:

96T

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 8

Cat.:

P0020Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 8

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P0020Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 8

Cat.:

P0020Rb-r

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40ug/0.2ml

Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 8

Protein for Human Tumor necrosis factor receptor superfamily member 8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease."
Duerkop H. , Latza U. , Hummel M. , Eitelbach F. , Seed B. , Stein H.
Cell68:421-427(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Lymphoid tissue.
2.

"Opposite effects of the CD30 ligand are not due to CD30 mutations: results from cDNA cloning and sequence comparison of the CD30 antigen from different sources."
Jung W. , Krueger S. , Renner C. , Gause A. , Sahin U. , Trumper L. , Pfreundschuh M.
Mol. Immunol.31:1329-1334(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages."
Horie R. , Ito K. , Tatewaki M. , Nagai M. , Aizawa S. , Higashihara M. , Ishida T. , Inoue J. , Takizawa H. , Watanabe T.
Blood88:2422-2432(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
4.

"Structure of the Hodgkin's disease associated human CD30 gene and the influence of a microsatellite region on its expression in CD30+ cell lines."
Durkop H. , Oberbarnscheidt M. , Latza U. , Bulfone-Paus S.
Submitted (2000-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORM 1)
tissue: Placenta.
5.

NIEHS SNPs program
Submitted (2003-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS TYR-273 AND GLY-402
6.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ARG-297
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
tissue: Blood.
tissue: Testis.
8.

"T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors."
Lee S.Y. , Park C.G. , Choi Y.
J. Exp. Med.183:669-674(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF1 AND TRAF2
9.

"Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily."
Boucher L.-M. , Marengere L.E. , Lu Y. , Thukral S. , Mak T.W.
Biochem. Biophys. Res. Commun.233:592-600(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF3
10.

"Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5)."
Mizushima S. , Fujita M. , Ishida T. , Azuma S. , Kato K. , Hirai M. , Otsuka M. , Yamamoto T. , Inoue J.
Gene207:135-140(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF5
11.

"Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation."
Aizawa S. , Nakano H. , Ishida T. , Horie R. , Nagai M. , Ito K. , Yagita H. , Okumura K. , Inoue J. , Watanabe T.
J. Biol. Chem.272:2042-2045(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF5
12.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-452;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
13.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-452;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"The structural basis for the recognition of diverse receptor sequences by TRAF2."
Ye H. , Park Y.C. , Kreishman M. , Kieff E. , Wu H.
Mol. Cell4:321-330(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 576-583 IN COMPLEX WITH TRAF2;INTERACTION WITH TRAF2

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