YY1 Protein for Human(Homo sapiens) | EIAab.comYY1 Protein for Human(Homo sapiens)

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Index > Protein center > YY1(Gene name) > Human

YY1 (Gene name),

Transcriptional repressor protein YY1 (Protein name ), TYY1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

YY1(INO80S);

Protein name:

Transcriptional repressor protein YY1;

Alternative:

INO80 complex subunit S;Delta transcription factor;Yin and yang 1(YY-1);NF-E1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with YAF2 through the region encompassing the first and second zinc fingers. Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Interacts with EED and EZH2; the interactions are indicative for an association with the PRC2/EED-EZH2 complex.

Function:

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; proposed to target the INO80 complex to YY1-responsive elements.

Subcellular Location:

Nucleus matrix Associated with the nuclear matrix.

Protein Attributes:

Sequence length:

414

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

414:

KSHILTHAKA | KNNQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P25490

String:

P25490

KEGG:

hsa:7528

Pfam:

PF00096

UniGene:

Hs.388927

STRING:

9606.ENSP00000262238

MIM:

600013

Uniprot:

P25490

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ELISA Kit for Human Transcriptional repressor protein YY1

Cat.:

E11942h

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Packing:

96T

ELISA Kit for Human Transcriptional repressor protein YY1

Cat.:

E11942m

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MSDS:

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Packing:

96T

CLIA Kit for Human Transcriptional repressor protein YY1

Cat.:

U11942m

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MSDS:

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Packing:

96T

CLIA Kit for Human Transcriptional repressor protein YY1

Cat.:

U11942h

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MSDS:

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96T

Polyclonal Antibody for Human Transcriptional repressor protein YY1

Cat.:

P11942Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Transcriptional repressor protein YY1

Cat.:

P11942Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Transcriptional repressor protein YY1

Protein for Human Transcriptional repressor protein YY1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Transcriptional repression by YY1, a human GLI-Kruppel-related protein, and relief of repression by adenovirus E1A protein."
Shi Y. , Seto E. , Chang L.-S. , Shenk T.
Cell67:377-388(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
2.

"Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site."
Park K. , Atchison M.
Proc. Natl. Acad. Sci. U.S.A.88:9804-9808(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Foreskin.
3.

Whitson R.H. , Huang T. , Dang J. , Itakura K.
Submitted (1992-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Lymph.
5.

"Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking."
McNeil S. , Guo B. , Stein J.L. , Lian J.B. , Bushmeyer S. , Seto E. , Atchison M.L. , Penman S. , van Wijnen A.J. , Stein G.S.
J. Cell. Biochem.68:500-510(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
6.

"Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1."
Kalenik J.L. , Chen D. , Bradley M.E. , Chen S.-J. , Lee T.-C.
Nucleic Acids Res.25:843-849(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH YAF2
7.

"Poly(ADP-ribosyl)ation of transcription factor Yin Yang 1 under conditions of DNA damage."
Oei S.L. , Shi Y.
Biochem. Biophys. Res. Commun.285:27-31(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POLY-ADP-RIBOSYLATION BY PARP1
8.

"The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos."
Satijn D.P.E. , Hamer K.M. , den Blaauwen J. , Otte A.P.
Mol. Cell. Biol.21:1360-1369(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EZH2 AND EZH2
9.

"SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer."
Lee K.H. , Evans S. , Ruan T.Y. , Lassar A.B.
Development131:4709-4723(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DNA-BINDING;IDENTIFICATION IN A COMPLEX WITH SMAD1 AND SMAD4
10.

"Transcription factor YY1: structure, function, and therapeutic implications in cancer biology."
Gordon S. , Akopyan G. , Garban H. , Bonavida B.
Oncogene25:1125-1142(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
11.

"YY1 functions with INO80 to activate transcription."
Cai Y. , Jin J. , Yao T. , Gottschalk A.J. , Swanson S.K. , Wu S. , Shi Y. , Washburn M.P. , Florens L. , Conaway R.C. , Conaway J.W.
Nat. Struct. Mol. Biol.14:872-874(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE INO80 COMPLEX
12.

"A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair."
Wu S. , Shi Y. , Mulligan P. , Gay F. , Landry J. , Liu H. , Lu J. , Qi H.H. , Wang W. , Nickoloff J.A. , Wu C. , Shi Y.
Nat. Struct. Mol. Biol.14:1165-1172(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DNA REPAIR;SUBCELLULAR LOCATION;DNA-BINDING;PROTEIN INTERACTION;IDENTIFICATION IN THE INO80 COMPLEX
13.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-247;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex."
Yao T. , Song L. , Jin J. , Cai Y. , Takahashi H. , Swanson S.K. , Washburn M.P. , Florens L. , Conaway R.C. , Cohen R.E. , Conaway J.W.
Mol. Cell31:909-917(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE INO80 COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY
15.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-247 AND THR-378;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
16.

"YY1's longer DNA-binding motifs."
Kim J. , Kim J.
Genomics93:152-158(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DNA-BINDING MOTIF
17.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-118 AND SER-247;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
18.

"Development and validation of a method for profiling post-translational modification activities using protein microarrays."
Del Rincon S.V. , Rogers J. , Widschwendter M. , Sun D. , Sieburg H.B. , Spruck C.
PLoS ONE5:E11332-E11332(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION
19.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-118;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
20.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.

"Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling."
Chen L. , Cai Y. , Jin J. , Florens L. , Swanson S.K. , Washburn M.P. , Conaway J.W. , Conaway R.C.
J. Biol. Chem.286:11283-11289(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE INO80 COMPLEX
22.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-118;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
23.

"Regulation of DU145 prostate cancer cell growth by Scm-like with four mbt domains 2."
Lee K. , Na W. , Maeng J.H. , Wu H. , Ju B.G.
J. Biosci.38:105-112(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SFMBT2;SUBCELLULAR LOCATION
24.

"Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator."
Houbaviy H.B. , Usheva A. , Shenk T. , Burley S.K.
Proc. Natl. Acad. Sci. U.S.A.93:13577-13582(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 304-414
25.

"Design, synthesis and structure of a zinc finger with an artificial beta-turn."
Viles J.H. , Patel S.U. , Mitchell J.B.O. , Moody C.M. , Justice D.E. , Uppenbrink J. , Doyle P.M. , Harris C.J. , Sadler P.J. , Thornton J.M.
J. Mol. Biol.279:973-986(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 353-379
26.

"A de novo paradigm for mental retardation."
Vissers L.E. , de Ligt J. , Gilissen C. , Janssen I. , Steehouwer M. , de Vries P. , van Lier B. , Arts P. , Wieskamp N. , del Rosario M. , van Bon B.W. , Hoischen A. , de Vries B.B. , Brunner H.G. , Veltman J.A.
Nat. Genet.42:1109-1112(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TYR-380

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