Protein name:
Vascular endothelial growth factor B (VEGF-B) ;
Alternative:
VEGF-related factor (VRF) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer; disulfide-linked. Can also form heterodimer with VEGF.
Function:
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Subcellular Location:
Secreted
Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Protein Attributes:
50:
MSPLLRRLLL | AALLQLAPAQ | APVSQPDAPG | HQRKVVSWID | VYTRATCQPR |
100:
EVVVPLTVEL | MGTVAKQLVP | SCVTVQRCGG | CCPDDGLECV | PTGQHQVRMQ |
150:
ILMIRYPSSQ | LGEMSLEEHS | QCECRPKKKD | SAVKPDRAAT | PHHRPQPRSV |
200:
PGWDSAPGAP | SPADITHPTP | APGPSAHAAP | STTSALTPGP | AAAAADAAAS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
Rat
ELISA Kit for Human VEGF-B
ELISA Kit for Human VEGF-B
ELISA Kit for Human VEGF-B
ELISA Kit for Human VEGF-B
CLIA Kit for Human VEGF-B
CLIA Kit for Human VEGF-B
CLIA Kit for Human VEGF-B
CLIA Kit for Human VEGF-B
Polyclonal Antibody for Human VEGF-B
Polyclonal Antibody for Human VEGF-B
Polyclonal Antibody for Human VEGF-B
Polyclonal Antibody for Human VEGF-B
Monoclonal Antibody for Human VEGF-B
Monoclonal Antibody for Human VEGF-B
Monoclonal Antibody for Human VEGF-B
Monoclonal Antibody for Human VEGF-B
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Cloning and characterization of a novel human gene related to vascular endothelial growth factor."
Grimmond S.
,
Lagercrantz J.
,
Drinkwater C.
,
Silins G.
,
Townson S.
,
Pollock P.
,
Gotley D.
,
Carson E.
,
Rakar S.
,
Nordenskjoeld M.
,
Ward L.
,
Hayward N.K.
,
Weber G.
Genome Res.6:124-131(1996)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS VEGF-B186 AND VEGF-B167)
tissue :
Fetal brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM VEGF-B186)
tissue :
Fibrosarcoma .
3.
"Vascular endothelial growth factor B, a novel growth factor for endothelial cells."
Olofsson B.
,
Pajusola K.
,
Kaipainen A.
,
von Euler G.
,
Joukov V.
,
Saksela O.
,
Orpana A.
,
Pettersson R.F.
,
Alitalo K.
,
Eriksson U.
Proc. Natl. Acad. Sci. U.S.A.93:2576-2581(1996)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM VEGF-B167)
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM VEGF-B186)
tissue :
Tonsil .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.48 ANGSTROMS) OF 31-129;DISULFIDE BONDS;SUBUNIT