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Index > Protein center > RLN2(Gene name) > Human
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  • RLN2 (Gene name),
  • Prorelaxin H2 (Protein name ),  REL2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    RLN2;
    Protein name:
    Prorelaxin H2;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of a B chain and an A chain linked by two disulfide bonds.
    Function:
    Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    185
    Sequence:
    50:
    MPRLFFFHLL | GVCLLLNQFS | RAVADSWMEE | VIKLCGRELV | RAQIAICGMS | 
    100:
    TWSKRSLSQE | DAPQTPRPVA | EIVPSFINKD | TETINMMSEF | VANLPQELKL | 
    150:
    TLSEMQPALP | QLQQHVPVLK | DSSLLFEEFK | KLIRNRQSEA | ADSSPSELKY | 
    185:
    LGLDTHSRKK | RQLYSALANK | CCHVGCTKRS | LARFC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    MIM:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Prorelaxin H2
    Cat.:
    E10572h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Prorelaxin H2
    Cat.:
    U10572h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Prorelaxin H2
    Cat.:
    P10572Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Prorelaxin H2
    Protein for Human Prorelaxin H2
    Cat.:
    R10572h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

    R&D Technical Data

    12% SDS-PAGE analysis

              12% SDS-PAGE analysis


    WB

          Western blot - Anti-RLN2 antibody

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones."
      Hudson P. , John M. , Crawford R. , Haralambidis J. , Scanlon D. , Gorman J. , Tregear G. , Shine J. , Niall H.
      EMBO J.3:2333-2339(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
    2. 2.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    4. 4.
      "Expression of human relaxin genes: characterization of a novel alternatively-spliced human relaxin mRNA species."
      Gunnersen J.M. , Fu P. , Roche P.J. , Tregear G.W.
      Mol. Cell. Endocrinol.118:85-94(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 71-185 (ISOFORM 2);TISSUE SPECIFICITY
      tissue: Prostate.
    5. 5.
      "Analysis of the 5'-upstream regions of the human relaxin H1 and H2 genes and their chromosomal localization on chromosome 9p24.1 by radiation hybrid and breakpoint mapping."
      Garibay-Tupas J.L. , Csiszar K. , Fox M. , Povey S. , Bryant-Greenwood G.D.
      J. Mol. Endocrinol.23:355-365(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-15
    6. 6.
      "Human seminal relaxin is a product of the same gene as human luteal relaxin."
      Winslow J.W. , Shih A. , Bourell J.H. , Weiss G. , Reed B. , Stults J.T. , Goldsmith L.T.
      Endocrinology130:2660-2668(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-51
      tissue: Semen.
    7. 7.
      "Structural characterization by mass spectrometry of native and recombinant human relaxin."
      Winslow J.W. , Griffin P.R. , Rinderknecht E. , Vandlen R.L.
      Biomed. Environ. Mass Spectrom.19:655-664(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-53 AND 162-185 (ISOFORM 1);PYROGLUTAMATE FORMATION AT GLN-162
    8. 8.
      "Total synthesis of human relaxin and human relaxin derivatives by solid-phase peptide synthesis and site-directed chain combination."
      Buellesbach E.E. , Schwabe C.
      J. Biol. Chem.266:10754-10761(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SYNTHESIS
    9. 9.
      "X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants."
      Eigenbrot C. , Randal M. , Quan C. , Burnier J. , O'Connell L. , Rinderknecht E. , Kossiakoff A.A.
      J. Mol. Biol.221:15-21(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS)
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