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Index > Protein center > ATP6AP2(Gene name) > Human
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  • ATP6AP2 (Gene name),
  • Renin receptor (Protein name ),  RENR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (2)
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  • Gene name:
    ATP6AP2(HT028;MSTP009;PSEC0072;ATP6IP2;CAPER;ELDF10);
    Protein name:
    Renin receptor;
    Alternative:
    ATPase H(+)-transporting lysosomal-interacting protein 2;ATPase H(+)-transporting lysosomal accessory protein 2;Embryonic liver differentiation factor 10;ER-localized type I transmembrane adaptor;Renin/prorenin receptor;N14F;Vacuolar ATP synthase membrane sector-associated protein M8-9(ATP6M8-9;V-ATPase M8.9 subunit);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with renin and the vacuolar proton-ATPase.
    Function:
    Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    350
    Sequence:
    50:
    MAVFVVLLAL | VAGVLGNEFS | ILKSPGSVVF | RNGNWPIPGE | RIPDVAALSM | 
    100:
    GFSVKEDLSW | PGLAVGNLFH | RPRATVMVMV | KGVNKLALPP | GSVISYPLEN | 
    150:
    AVPFSLDSVA | NSIHSLFSEE | TPVVLQLAPS | EERVYMVGKA | NSVFEDLSVT | 
    200:
    LRQLRNRLFQ | ENSVLSSLPL | NSLSRNNEVD | LLFLSELQVL | HDISSLLSRH | 
    250:
    KHLAKDHSPD | LYSLELAGLD | EIGKRYGEDS | EQFRDASKIL | VDALQKFADD | 
    300:
    MYSLYGGNAV | VELVTVKSFD | TSLIRKTRTI | LEAKQAKNPA | SPYNLAYKYN | 
    350:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Renin receptor
    Cat.:
    E1093h
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    96T
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    ELISA Kit for Human Renin receptor
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    E1093m
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    Packing:
    96T
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    ELISA Kit for Human Renin receptor
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    E1093r
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    96T
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    ELISA Kit for Human Renin receptor
    Cat.:
    E1093b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Renin receptor
    Cat.:
    U1093r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Renin receptor
    Cat.:
    U1093m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Renin receptor
    Cat.:
    U1093h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Renin receptor
    Cat.:
    U1093b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Renin receptor
    Cat.:
    P1093Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Renin receptor
    Cat.:
    P1093Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Renin receptor
    Cat.:
    P1093Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Renin receptor
    Monoclonal Antibody for Human Renin receptor
    Monoclonal Antibody for Human Renin receptor
    Monoclonal Antibody for Human Renin receptor
    Monoclonal Antibody for Human Renin receptor
    Protein for Human Renin receptor
    Protein for Human Renin receptor
    Protein for Human Renin receptor
    Protein for Human Renin receptor

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    References
    1. 1.
      "Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin."
      Nguyen G. , Delarue F. , Burckle C. , Bouzhir L. , Giller T. , Sraer J.-D.
      J. Clin. Invest.109:1417-1427(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH REN;PHOSPHORYLATION;TISSUE SPECIFICITY;FUNCTION
      tissue: Mesangial cell.
    2. 2.
      "Cell cycle-dependent subcellular localization of the protein tyrosine phosphatase PTPCAAX1 and its implication in cell cycle regulation."
      Wang J. , Kirby C. , Herbst R.
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Cervix carcinoma.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Aorta.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Hypothalamus.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain cortex.
    6. 6.
      "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
      Otsuki T. , Ota T. , Nishikawa T. , Hayashi K. , Suzuki Y. , Yamamoto J. , Wakamatsu A. , Kimura K. , Sakamoto K. , Hatano N. , Kawai Y. , Ishii S. , Saito K. , Kojima S. , Sugiyama T. , Ono T. , Okano K. , Yoshikawa Y. , more...
      DNA Res.12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Teratocarcinoma.
    7. 7.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Prostate.
    9. 9.
      "The cloning of a novel gene related with erythroid differentiation."
      Zhang S. , Yan H. , Yang F.
      Submitted (2003-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 13-350 (ISOFORM 1)
      tissue: Liver.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 21-350 (ISOFORM 1)
      tissue: Brain.
    11. 11.
      "Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules."
      Ludwig J. , Kerscher S. , Brandt U. , Pfeiffer K. , Getlawi F. , Apps D.K. , Schaegger H.
      J. Biol. Chem.273:10939-10947(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 188-350 (ISOFORM 1)
    12. 12.
      "A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor."
      Ramser J. , Abidi F.E. , Burckle C.A. , Lenski C. , Toriello H. , Wen G. , Lubs H.A. , Engert S. , Stevenson R.E. , Meindl A. , Schwartz C.E. , Nguyen G.
      Hum. Mol. Genet.14:1019-1027(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN MRXE;TISSUE SPECIFICITY;ALTERNATIVE SPLICING
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN XPDS
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