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Index > Protein center > RHOC(Gene name) > Human
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  • RHOC (Gene name),
  • Rho-related GTP-binding protein RhoC (Protein name ),  RHOC_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    RHOC(ARH9;ARHC);
    Protein name:
    Rho-related GTP-binding protein RhoC;
    Alternative:
    Rho cDNA clone 9(h9);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with DIAPH1, ROCK1, ROCK2 and RTKN. Interacts with AKAP13.
    Function:
    Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    Subcellular Location:
    Cell membrane Lipid-anchor Cytoplasmic side
    Protein Attributes:
    Sequence length:
    193
    Sequence:
    50:
    MAAIRKKLVI | VGDGACGKTC | LLIVFSKDQF | PEVYVPTVFE | NYIADIEVDG | 
    100:
    KQVELALWDT | AGQEDYDRLR | PLSYPDTDVI | LMCFSIDSPD | SLENIPEKWT | 
    150:
    PEVKHFCPNV | PIILVGNKKD | LRQDEHTRRE | LAKMKQEPVR | SEEGRDMANR | 
    193:
    ISAFGYLECS | AKTKEGVREV | FEMATRAGLQ | VRKNKRRRGC | PIL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    SMR:
    MIM:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Rho-related GTP-binding protein RhoC
    Cat.:
    E10923h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Rho-related GTP-binding protein RhoC
    MSDS:
    Please sign in first.
    ELISA Kit for Human Rho-related GTP-binding protein RhoC
    MSDS:
    Please sign in first.
    ELISA Kit for Human Rho-related GTP-binding protein RhoC
    Cat.:
    E10923m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Rho-related GTP-binding protein RhoC
    MSDS:
    Please sign in first.
    CLIA Kit for Human Rho-related GTP-binding protein RhoC
    MSDS:
    Please sign in first.
    CLIA Kit for Human Rho-related GTP-binding protein RhoC
    Cat.:
    U10923h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Rho-related GTP-binding protein RhoC
    Cat.:
    U10923m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Rho-related GTP-binding protein RhoC
    Polyclonal Antibody for Human Rho-related GTP-binding protein RhoC
    Polyclonal Antibody for Human Rho-related GTP-binding protein RhoC
    Cat.:
    P10923Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Rho-related GTP-binding protein RhoC
    Monoclonal Antibody for Human Rho-related GTP-binding protein RhoC
    Monoclonal Antibody for Human Rho-related GTP-binding protein RhoC
    Monoclonal Antibody for Human Rho-related GTP-binding protein RhoC
    Monoclonal Antibody for Human Rho-related GTP-binding protein RhoC
    Protein for Human Rho-related GTP-binding protein RhoC
    Protein for Human Rho-related GTP-binding protein RhoC
    Protein for Human Rho-related GTP-binding protein RhoC
    Protein for Human Rho-related GTP-binding protein RhoC

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    Precision
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    Linearity
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    References
    1. 1.
      "Coding sequence of human rho cDNAs clone 6 and clone 9."
      Chardin P. , Madaule P. , Tavitian A.
      Nucleic Acids Res.16:2717-2717(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Fagan K.P. , Oliveira L. , Pittler S.J.
      Submitted (1993-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Retina.
    3. 3.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Puhl H.L. III , Ikeda S.R. , Aronstam R.S.
      Submitted (2002-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Cerebellum.
    7. 7.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skin.
    10. 10.
      "The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton."
      Leung T. , Chen X.-Q. , Manser E. , Lim L.
      Mol. Cell. Biol.16:5313-5327(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ROCK1 AND ROCK2
    11. 11.
      "AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation."
      Diviani D. , Soderling J. , Scott J.D.
      J. Biol. Chem.276:44247-44257(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AKAP13
    12. 12.
      "Dissecting the role of Rho-mediated signaling in contractile ring formation."
      Kamijo K. , Ohara N. , Abe M. , Uchimura T. , Hosoya H. , Lee J.S. , Miki T.
      Mol. Biol. Cell17:43-55(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    13. 13.
      "Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1."
      Boulter E. , Garcia-Mata R. , Guilluy C. , Dubash A. , Rossi G. , Brennwald P.J. , Burridge K.
      Nat. Cell Biol.12:477-483(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ARHGDIA
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells."
      Wallace S.W. , Magalhaes A. , Hall A.
      Mol. Cell. Biol.31:81-91(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PKN2
    16. 16.
      "Structural and mechanistic insights into the interaction between Rho and mammalian Dia."
      Rose R. , Weyand M. , Lammers M. , Ishizaki T. , Ahmadian M.R. , Wittinghofer A.
      Nature435:513-518(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) IN COMPLEX WITH DIAPH1
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