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Index > Protein center > S100A1(Gene name) > Human
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  • S100A1 (Gene name),
  • Protein S100-A1 (Protein name ),  S10A1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    S100A1(S100A);
    Protein name:
    Protein S100-A1;
    Alternative:
    S-100 protein subunit alpha;S-100 protein alpha chain;S100 calcium-binding protein A1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. Interacts with AGER and CAPZA1 (By similarity). Interacts with FKBP4.
    Function:
    Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    94
    Sequence:
    50:
    MGSELETAME | TLINVFHAHS | GKEGDKYKLS | KKELKELLQT | ELSGFLDAQK | 
    94:
    DVDAVDKVMK | ELDENGDGEV | DFQEYVVLVA | ALTVACNNFF | WENS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    MIM:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein S100-A1
    Cat.:
    E14940h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Protein S100-A1
    Cat.:
    E14940m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human Protein S100-A1
    MSDS:
    Please sign in first.
    ELISA Kit for Human Protein S100-A1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Protein S100-A1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Protein S100-A1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Protein S100-A1
    Cat.:
    U14940m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Protein S100-A1
    Cat.:
    U14940h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Protein S100-A1
    Polyclonal Antibody for Human Protein S100-A1
    Polyclonal Antibody for Human Protein S100-A1
    Polyclonal Antibody for Human Protein S100-A1
    Monoclonal Antibody for Human Protein S100-A1
    Monoclonal Antibody for Human Protein S100-A1
    Monoclonal Antibody for Human Protein S100-A1
    Monoclonal Antibody for Human Protein S100-A1
    Protein for Human Protein S100-A1
    Protein for Human Protein S100-A1
    Protein for Human Protein S100-A1
    Protein for Human Protein S100-A1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "S100 alpha, CAPL, and CACY: molecular cloning and expression analysis of three calcium-binding proteins from human heart."
      Engelkamp D. , Schaefer B.W. , Erne P. , Heizmann C.W.
      Biochemistry31:10258-10264(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Heart.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Caudate nucleus.
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
      Goshima N. , Kawamura Y. , Fukumoto A. , Miura A. , Honma R. , Satoh R. , Wakamatsu A. , Yamamoto J. , Kimura K. , Nishikawa T. , Andoh T. , Iida Y. , Ishikawa K. , Ito E. , Kagawa N. , Kaminaga C. , Kanehori K. , Kawakami B. , more...
      Nat. Methods5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skin.
    8. 8.
      "CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family."
      Filipek A. , Jastrzebska B. , Nowotny M. , Kuznicki J.
      J. Biol. Chem.277:28848-28852(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CACYBP
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH S100P
    10. 10.
      "S100A1 and calmodulin compete for the same binding site on ryanodine receptor."
      Wright N.T. , Prosser B.L. , Varney K.M. , Zimmer D.B. , Schneider M.F. , Weber D.J.
      J. Biol. Chem.283:26676-26683(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RYR1 AND RYR2
    11. 11.
      "S100 proteins regulate the interaction of Hsp90 with cyclophilin 40 and FKBP52 through their tetratricopeptide repeats."
      Shimamoto S. , Kubota Y. , Tokumitsu H. , Kobayashi R.
      FEBS Lett.584:1119-1125(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FKBP4
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "S100 proteins modulate protein phosphatase 5 function: a link between CA2+ signal transduction and protein dephosphorylation."
      Yamaguchi F. , Umeda Y. , Shimamoto S. , Tsuchiya M. , Tokumitsu H. , Tokuda M. , Kobayashi R.
      J. Biol. Chem.287:13787-13798(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PPP5C
    14. 14.
      "Solution NMR structure and dynamics of human apo-S100A1 protein."
      Nowakowski M. , Jaremko L. , Jaremko M. , Zhukov I. , Belczyk A. , Bierzynski A. , Ejchart A.
      J. Struct. Biol.174:391-399(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR;SUBUNIT
    15. 15.
      "Post-translational S-nitrosylation is an endogenous factor fine tuning the properties of human S100A1 protein."
      Lenarcic Zivkovic M. , Zareba-Koziol M. , Zhukova L. , Poznanski J. , Zhukov I. , Wyslouch-Cieszynska A.
      J. Biol. Chem.287:40457-40470(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 2-94;S-NITROSYLATION AT CYS-86
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