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Index > Protein center > SLC29A1(Gene name) > Human
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  • SLC29A1 (Gene name),
  • Equilibrative nucleoside transporter 1 (Protein name ),  S29A1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC29A1(ENT1);
    Protein name:
    Equilibrative nucleoside transporter 1;
    Alternative:
    Nucleoside transporter, es-type;Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter(Equilibrative NBMPR-sensitive nucleoside transporter);Solute carrier family 29 member 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
    Subcellular Location:
    Basolateral cell membrane Multi-pass membrane protein Apical cell membrane Multi-pass membrane protein Predominantly localized in the basolateral membrane in polarised MDCK cells.
    Protein Attributes:
    Sequence length:
    456
    Sequence:
    50:
    MTTSHQPQDR | YKAVWLIFFM | LGLGTLLPWN | FFMTATQYFT | NRLDMSQNVS | 
    100:
    LVTAELSKDA | QASAAPAAPL | PERNSLSAIF | NNVMTLCAML | PLLLFTYLNS | 
    150:
    FLHQRIPQSV | RILGSLVAIL | LVFLITAILV | KVQLDALPFF | VITMIKIVLI | 
    200:
    NSFGAILQGS | LFGLAGLLPA | SYTAPIMSGQ | GLAGFFASVA | MICAIASGSE | 
    250:
    LSESAFGYFI | TACAVIILTI | ICYLGLPRLE | FYRYYQQLKL | EGPGEQETKL | 
    300:
    DLISKGEEPR | AGKEESGVSV | SNSQPTNESH | SIKAILKNIS | VLAFSVCFIF | 
    350:
    TITIGMFPAV | TVEVKSSIAG | SSTWERYFIP | VSCFLTFNIF | DWLGRSLTAV | 
    400:
    FMWPGKDSRW | LPSLVLARLV | FVPLLLLCNI | KPRRYLTVVF | EHDAWFIFFM | 
    450:
    AAFAFSNGYL | ASLCMCFGPK | KVKPAEAETA | GAIMAFFLCL | GLALGAVFSF | 
    456:
    LFRAIV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    MIM:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Equilibrative nucleoside transporter 1
    Cat.:
    E11051h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Equilibrative nucleoside transporter 1
    Cat.:
    E11051m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Equilibrative nucleoside transporter 1
    Cat.:
    E11051r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Equilibrative nucleoside transporter 1
    Cat.:
    U11051h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Equilibrative nucleoside transporter 1
    Cat.:
    U11051m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Equilibrative nucleoside transporter 1
    Cat.:
    U11051r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Equilibrative nucleoside transporter 1
    Polyclonal Antibody for Human Equilibrative nucleoside transporter 1
    Polyclonal Antibody for Human Equilibrative nucleoside transporter 1
    Cat.:
    P11051Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Equilibrative nucleoside transporter 1
    Monoclonal Antibody for Human Equilibrative nucleoside transporter 1
    Monoclonal Antibody for Human Equilibrative nucleoside transporter 1
    Protein for Human Equilibrative nucleoside transporter 1
    Protein for Human Equilibrative nucleoside transporter 1
    Protein for Human Equilibrative nucleoside transporter 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs."
      Griffiths M. , Beaumont N. , Yao S.Y.M. , Sundaram M. , Boumah C.E. , Davies A. , Kwong F.Y.P. , Coe I. , Cass C.E. , Young J.D. , Baldwin S.A.
      Nat. Med.3:89-93(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 2-22
      tissue: Placenta.
    2. 2.
      "Genomic sequence of the human equilibrative nucleoside transporter 1 (hENT1)."
      Graham K.A. , Coe I.R. , Carpenter P. , Baldwin S.A. , Young J.D. , Cass C.E.
      Submitted (1999-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Human intestinal es nucleoside transporter: molecular characterization and nucleoside inhibitory profiles."
      Lum P.Y. , Ngo L.Y. , Bakken A.H. , Unadkat J.D.
      Cancer Chemother. Pharmacol.45:273-278(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Jejunum.
      tissue: Small intestine.
    4. 4.
      "Comparative genomic analysis of equilibrative nucleoside transporters suggests conserved protein structure despite limited sequence identity."
      Sankar N. , Machado J. , Abdulla P. , Hilliker A.J. , Coe I.R.
      Nucleic Acids Res.30:4339-4350(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells."
      Mangravite L.M. , Xiao G. , Giacomini K.M.
      Am. J. Physiol.284:F902-F910(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;SUBCELLULAR LOCATION;BIOPHYSICOCHEMICAL PROPERTIES;MUTAGENESIS OF ARG-453 AND 453-ARG--VAL-456
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Adrenal gland.
    7. 7.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Colon.
      tissue: Muscle.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-48
      tissue: Leukemic T-cell.
    12. 12.
      "Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains."
      Rungaldier S. , Oberwagner W. , Salzer U. , Csaszar E. , Prohaska R.
      Biochim. Biophys. Acta1828:956-966(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;IDENTIFICATION IN A COMPLEX WITH STOM;SUBUNIT
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] THR-293 AND VAL-455
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