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Index > Protein center > APCS(Gene name) > Human
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  • APCS (Gene name),
  • Serum amyloid P-component (Protein name ),  SAMP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (1)
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  • Gene name:
    APCS(PTX2);
    Protein name:
    Serum amyloid P-component(SAP);
    Alternative:
    9.5S alpha-1-glycoprotein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
    Function:
    Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    223
    Sequence:
    50:
    MNKPLLWISV | LTSLLEAFAH | TDLSGKVFVF | PRESVTDHVN | LITPLEKPLQ | 
    100:
    NFTLCFRAYS | DLSRAYSLFS | YNTQGRDNEL | LVYKERVGEY | SLYIGRHKVT | 
    150:
    SKVIEKFPAP | VHICVSWESS | SGIAEFWING | TPLVKKGLRQ | GYFVEAQPKI | 
    200:
    VLGQEQDSYG | GKFDRSQSFV | GEIGDLYMWD | SVLPPENILS | AYQGTPLPAN | 
    223:
    ILDWQALNYE | IRGYVIIKPL | VWV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    MIM:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human SAP
    Cat.:
    E1539h
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    96T
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    ELISA Kit for Human SAP
    Cat.:
    E1539b
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    Packing:
    96T
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    ELISA Kit for Human SAP
    Cat.:
    E1539m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human SAP
    Cat.:
    E1539p
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    MSDS:
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    96T
    ELISA Kit for Human SAP
    Cat.:
    E1539r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human SAP
    Cat.:
    U1539p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human SAP
    Cat.:
    U1539b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human SAP
    Cat.:
    U1539h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human SAP
    Cat.:
    U1539r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human SAP
    Cat.:
    U1539m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human SAP
    Cat.:
    P1539Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human SAP
    Polyclonal Antibody for Human SAP
    Cat.:
    P1539Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human SAP
    Cat.:
    P1539Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human SAP
    Monoclonal Antibody for Human SAP
    Monoclonal Antibody for Human SAP
    Monoclonal Antibody for Human SAP
    Monoclonal Antibody for Human SAP
    Monoclonal Antibody for Human SAP
    Protein for Human SAP
    Protein for Human SAP
    Protein for Human SAP
    Protein for Human SAP
    Protein for Human SAP

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    References
    1. 1.
      "Human serum amyloid P component. cDNA isolation, complete sequence of pre-serum amyloid P component, and localization of the gene to chromosome 1."
      Mantzouranis E.C. , Dowton S.B. , Whitehead A.S. , Edge M.D. , Bruns G.A.P. , Colten H.R.
      J. Biol. Chem.260:7752-7756(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Isolation and characterization of the complete complementary and genomic DNA sequences of human serum amyloid P component."
      Ohnishi S. , Maeda S. , Shimada K. , Arao T.
      J. Biochem.100:849-858(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skeletal muscle.
    7. 7.
      "The primary structure of human tissue amyloid P component from a patient with primary idiopathic amyloidosis."
      Prelli F. , Pras M. , Frangione B.
      J. Biol. Chem.260:12895-12898(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-223
    8. 8.
      "Human plasma P component: isolation and characterization."
      Thompson A.R. , Enfield D.L.
      Biochemistry17:4304-4311(1978) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-49
    9. 9.
      "Human serum amyloid P component is an invariant constituent of amyloid deposits and has a uniquely homogeneous glycostructure."
      Pepys M.B. , Rademacher T.W. , Amatayakul-Chantler S. , Williams P. , Noble G.E. , Hutchinson W.L. , Hawkins P.N. , Nelson S.R. , Gallimore J.R. , Herbert J. , Hutton T. , Dwek R.A.
      Proc. Natl. Acad. Sci. U.S.A.91:5602-5606(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE OF CARBOHYDRATE;MASS SPECTROMETRY
    10. 10.
      "Proteomic characterization of novel serum amyloid P component variants from human plasma and urine."
      Kiernan U.A. , Nedelkov D. , Tubbs K.A. , Niederkofler E.E. , Nelson R.W.
      Proteomics4:1825-1829(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;MASS SPECTROMETRY
    11. 11.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-51
      tissue: Plasma.
    12. 12.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-51
      tissue: Liver.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS)
    15. 15.
      "Crystal structure of a decameric complex of human serum amyloid P component with bound dAMP."
      Hohenester E. , Hutchinson W.L. , Pepys M.B. , Wood S.P.
      J. Mol. Biol.269:570-578(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS)
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] SER-141
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