Gene name:
SELS (AD-015;SBBI8;VIMP) ;
Protein name:
Selenoprotein S (SelS) ;
Alternative:
VCP-interacting membrane protein ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with DERL1 and VCP, suggesting that it forms a membrane complex with DERL1 that serves as a receptor for VCP.
Function:
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass membrane protein
Cytoplasm
Protein Attributes:
50:
MERQEESLSA | RPALETEGLR | FLHTTVGSLL | ATYGWYIVFS | CILLYVVFQK |
100:
LSARLRALRQ | RQLDRAAAAV | EPDVVVKRQE | ALAAARLKMQ | EELNAQVEKH |
150:
KEKLKQLEEE | KRRQKIEMWD | SMQEGKSYKG | NAKKPQEEDS | PGPSTSSVLK |
189:
RKSDRKPLRG | GGYNPLSGEG | GGACSWRPGR | RGPSSGGUG
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Human
Bovine
Mouse
Rat
Polyclonal Antibody for Human SelS
Polyclonal Antibody for Human SelS
Polyclonal Antibody for Human SelS
Polyclonal Antibody for Human SelS
Polyclonal Antibody for Human SelS
Monoclonal Antibody for Human SelS
Monoclonal Antibody for Human SelS
Monoclonal Antibody for Human SelS
Monoclonal Antibody for Human SelS
Monoclonal Antibody for Human SelS
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SELK; DERL1; DERL2 AND DERL3;IDENTIFICATION IN A COMPLEX WITH CANX; DERL1; DERL2; DDOST; RPN1; RPN2; SELK; STT3A AND VCP