Gene name:
SEMA4D (C9orf164;CD100;SEMAJ) ;
Protein name:
Semaphorin-4D ;
Alternative:
BB18 ;A8 ;GR3 ;
CD:
CD100 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer. Binds PLXNB1.
Function:
May play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MRMCTPIRGL | LMALAVMFGT | AMAFAPIPRI | TWEHREVHLV | QFHEPDIYNY |
100:
SALLLSEDKD | TLYIGAREAV | FAVNALNISE | KQHEVYWKVS | EDKKAKCAEK |
150:
GKSKQTECLN | YIRVLQPLSA | TSLYVCGTNA | FQPACDHLNL | TSFKFLGKNE |
200:
DGKGRCPFDP | AHSYTSVMVD | GELYSGTSYN | FLGSEPIISR | NSSHSPLRTE |
250:
YAIPWLNEPS | FVFADVIRKS | PDSPDGEDDR | VYFFFTEVSV | EYEFVFRVLI |
300:
PRIARVCKGD | QGGLRTLQKK | WTSFLKARLI | CSRPDSGLVF | NVLRDVFVLR |
350:
SPGLKVPVFY | ALFTPQLNNV | GLSAVCAYNL | STAEEVFSHG | KYMQSTTVEQ |
400:
SHTKWVRYNG | PVPKPRPGAC | IDSEARAANY | TSSLNLPDKT | LQFVKDHPLM |
450:
DDSVTPIDNR | PRLIKKDVNY | TQIVVDRTQA | LDGTVYDVMF | VSTDRGALHK |
500:
AISLEHAVHI | IEETQLFQDF | EPVQTLLLSS | KKGNRFVYAG | SNSGVVQAPL |
550:
AFCGKHGTCE | DCVLARDPYC | AWSPPTATCV | ALHQTESPSR | GLIQEMSGDA |
600:
SVCPDKSKGS | YRQHFFKHGG | TAELKCSQKS | NLARVFWKFQ | NGVLKAESPK |
650:
YGLMGRKNLL | IFNLSEGDSG | VYQCLSEERV | KNKTVFQVVA | KHVLEVKVVP |
700:
KPVVAPTLSV | VQTEGSRIAT | KVLVASTQGS | SPPTPAVQAT | SSGAITLPPK |
750:
PAPTGTSCEP | KIVINTVPQL | HSEKTMYLKS | SDNRLLMSLF | LFFFVLFLCL |
800:
FFYNCYKGYL | PRQCLKFRSA | LLIGKKKPKS | DFCDREQSLK | ETLVEPGSFS |
850:
QQNGEHPKPA | LDTGYETEQD | TITSKVPTDR | EDSQRIDDLS | ARDKPFDVKC |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
ELISA Kit for Human Semaphorin-4D
ELISA Kit for Human Semaphorin-4D
ELISA Kit for Human Semaphorin-4D
CLIA Kit for Human Semaphorin-4D
CLIA Kit for Human Semaphorin-4D
CLIA Kit for Human Semaphorin-4D
Polyclonal Antibody for Human Semaphorin-4D
Polyclonal Antibody for Human Semaphorin-4D
Polyclonal Antibody for Human Semaphorin-4D
Monoclonal Antibody for Human Semaphorin-4D
Monoclonal Antibody for Human Semaphorin-4D
Monoclonal Antibody for Human Semaphorin-4D
Protein for Human Semaphorin-4D
Protein for Human Semaphorin-4D
Protein for Human Semaphorin-4D
R&D Technical Data
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Precision
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Recovery
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Linearity
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T-cell .
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Brain .
tissue :
Eye .
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[
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[
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[
Abstract ]
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Cited for : PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Small intestine .
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Cell99:71-80(1999)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PLXNB1
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
7.
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Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-419
tissue :
Platelet .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-49; ASN-74; ASN-77; ASN-379 AND ASN-419
tissue :
Leukemic T-cell .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 24-684;DISULFIDE BONDS
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.99 ANGSTROMS) OF 22-677 IN COMPLEX WITH PLXNB1;SUBUNIT;FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF 100-LYS-GLY-101; 181-PHE-LEU-182; PHE-244; PHE-246 AND LYS-395;GLYCOSYLATION AT ASN-49; ASN-77; ASN-139; ASN-191; ASN-329 AND ASN-419;DISULFIDE BONDS