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Index > Protein center > SEMG1(Gene name) > Human
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  • SEMG1 (Gene name),
  • Semenogelin-1 (Protein name ),  SEMG1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    SEMG1(SEMG);
    Protein name:
    Semenogelin-1;
    Alternative:
    Semenogelin I(SGI);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Occurs in disulfide-linked complexes which may also contain two less abundant 71- and 76-kDa semenogelin-related polypeptides.
    Function:
    Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    462
    Sequence:
    50:
    MKPNIIFVLS | LLLILEKQAA | VMGQKGGSKG | RLPSEFSQFP | HGQKGQHYSG | 
    100:
    QKGKQQTESK | GSFSIQYTYH | VDANDHDQSR | KSQQYDLNAL | HKTTKSQRHL | 
    150:
    GGSQQLLHNK | QEGRDHDKSK | GHFHRVVIHH | KGGKAHRGTQ | NPSQDQGNSP | 
    200:
    SGKGISSQYS | NTEERLWVHG | LSKEQTSVSG | AQKGRKQGGS | QSSYVLQTEE | 
    250:
    LVANKQQRET | KNSHQNKGHY | QNVVEVREEH | SSKVQTSLCP | AHQDKLQHGS | 
    300:
    KDIFSTQDEL | LVYNKNQHQT | KNLNQDQQHG | RKANKISYQS | SSTEERRLHY | 
    350:
    GENGVQKDVS | QSSIYSQTEE | KAQGKSQKQI | TIPSQEQEHS | QKANKISYQS | 
    400:
    SSTEERRLHY | GENGVQKDVS | QRSIYSQTEK | LVAGKSQIQA | PNPKQEPWHG | 
    450:
    ENAKGESGQS | TNREQDLLSH | EQKGRHQHGS | HGGLDIVIIE | QEDDSDRHLA | 
    462:
    QHLNNDRNPL | FT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    KEGG:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Semenogelin-1
    Cat.:
    E13150h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Semenogelin-1
    Cat.:
    U13150h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Semenogelin-1
    Monoclonal Antibody for Human Semenogelin-1
    Protein for Human Semenogelin-1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Semenogelin, the predominant protein in human semen. Primary structure and identification of closely related proteins in the male accessory sex glands and on the spermatozoa."
      Lilja H. , Abrahamsson P.-A. , Lundwall A.
      J. Biol. Chem.264:1894-1900(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Gene structure of semenogelin I and II. The predominant proteins in human semen are encoded by two homologous genes on chromosome 20."
      Ulvsbaeck M. , Lazure C. , Lilja H. , Spurr N.K. , Rao V.V. , Loeffler C. , Hansmann I. , Lundwall A.
      J. Biol. Chem.267:18080-18084(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Blood.
    3. 3.
      "Evolution of the hominoid semenogelin genes, the major proteins of ejaculated semen."
      Jensen-Seaman M.I. , Li W.-H.
      J. Mol. Evol.57:261-270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS THR-79 AND LEU-372
    4. 4.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    5. 5.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Prostate.
    8. 8.
      "Reduced polymorphism in the chimpanzee semen coagulating protein, semenogelin I."
      Kingan S.B. , Tatar M. , Rand D.M.
      J. Mol. Evol.57:159-169(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 62-237 AND 241-449;VARIANT THR-79
    9. 9.
      "Amino acid sequence of the predominant basic protein in human seminal plasma."
      Lilja H. , Jeppsson J.-O.
      FEBS Lett.182:181-184(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 108-159
    10. 10.
      "Partial amino acid sequence of a human seminal plasma peptide with inhibin-like activity."
      Seidah N.G. , Ramasharma K. , Sairam M.R. , Chretien M.
      FEBS Lett.167:98-102(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 108-138
    11. 11.
      "Isolation, structure, and synthesis of a human seminal plasma peptide with inhibin-like activity."
      Ramasharma K. , Sairam M.R. , Seidah N.G. , Chretien M. , Manjunath P. , Schiller P.W. , Yamashiro D. , Li C.H.
      Science223:1199-1202(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 108-138
    12. 12.
      "Isolation and structure determination of two peptides occurring in human seminal plasma."
      Schneider K. , Kausler W. , Tripier D. , Jouvenal K. , Spiteller G.
      Biol. Chem. Hoppe-Seyler370:353-356(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 316-344
    13. 13.
      "Isolation and identification of N-terminally extended forms of 5-oxoprolylglutamylprolinamide (Glp-Glu-Pro-NH2), a thyrotropin-releasing-hormone (TRH)-like peptide present in human semen."
      Khan Z. , Smyth D.G.
      Eur. J. Biochem.212:35-40(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 373-397
    14. 14.
      "Human seminal alpha inhibins: isolation, characterization, and structure."
      Li C.H. , Hammonds R.G. , Ramasharma K. , Chung D.
      Proc. Natl. Acad. Sci. U.S.A.82:4041-4044(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 68-159
    15. 15.
      "Semenogelin I: a coagulum forming, multifunctional seminal vesicle protein."
      Robert M. , Gagnon C.
      Cell. Mol. Life Sci.55:944-960(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    16. 16.
      "Association of eppin with semenogelin on human spermatozoa."
      Wang Z. , Widgren E.E. , Sivashanmugam P. , O'Rand M.G. , Richardson R.T.
      Biol. Reprod.72:1064-1070(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EPPIN
    17. 17.
      "Characterization of an eppin protein complex from human semen and spermatozoa."
      Wang Z. , Widgren E.E. , Richardson R.T. , O'Rand M.G.
      Biol. Reprod.77:476-484(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH LTF; CLU AND EPPIN
    18. 18.
      "Analysis of recombinant human semenogelin as an inhibitor of human sperm motility."
      Mitra A. , Richardson R.T. , O'Rand M.G.
      Biol. Reprod.82:489-496(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF CYS-239
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