NAD-dependent deacetylase sirtuin-2 (Protein name
), SIRT2_HUMAN from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Related Databases
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Gene name:
SIRT2(SIR2L;SIR2L2);
Protein name:
NAD-dependent deacetylase sirtuin-2;
Alternative:
SIR2-like protein 2;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with HDAC6, suggesting that these proteins belong to a large complex that deacetylate the cytoskeleton.
Function:
NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton.
Subcellular Location:
Cytoplasm
cytoskeleton
Colocalizes with microtubules.
Monoclonal Antibody for Human NAD-dependent deacetylase sirtuin-2
Monoclonal Antibody for Human NAD-dependent deacetylase sirtuin-2
Monoclonal Antibody for Human NAD-dependent deacetylase sirtuin-2
Monoclonal Antibody for Human NAD-dependent deacetylase sirtuin-2
Monoclonal Antibody for Human NAD-dependent deacetylase sirtuin-2
Monoclonal Antibody for Human NAD-dependent deacetylase sirtuin-2
Protein for Human NAD-dependent deacetylase sirtuin-2
Protein for Human NAD-dependent deacetylase sirtuin-2
Protein for Human NAD-dependent deacetylase sirtuin-2
Protein for Human NAD-dependent deacetylase sirtuin-2
Protein for Human NAD-dependent deacetylase sirtuin-2
Protein for Human NAD-dependent deacetylase sirtuin-2
R&D Technical Data
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Precision
Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤7.8%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤10.9%
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Recovery
Recovery was determined by spiking various levels of SIRT2 into serum and plasma .
Sample Type
Average(%)
Recovery Range(%)
Serum
99
95-103
Plasma
98
96-101
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Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of SIRT2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Sample
1:2
1:4
1:8
1:16
serum(n=5)
91-107%
93-104%
92-104%
95-103%
EDTA plasma(n=5)
92-105%
94-105%
93-105%
93-106%
heparin plasma(n=5)
95-102%
96-102%
94-102%
96-101%
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