Gene name:
SERPINB6 (PI6;PTI) ;
Protein name:
Serpin B6 ;
Alternative:
Peptidase inhibitor 6 (PI-6) ;Cytoplasmic antiproteinase (CAP) ;Placental thrombin inhibitor ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Forms a complex with the monomeric form of beta-tryptase.
Function:
May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MDVLAEANGT | FALNLLKTLG | KDNSKNVFFS | PMSMSCALAM | VYMGAKGNTA |
100:
AQMAQILSFN | KSGGGGDIHQ | GFQSLLTEVN | KTGTQYLLRM | ANRLFGEKSC |
150:
DFLSSFRDSC | QKFYQAEMEE | LDFISAVEKS | RKHINTWVAE | KTEGKIAELL |
200:
SPGSVDPLTR | LVLVNAVYFR | GNWDEQFDKE | NTEERLFKVS | KNEEKPVQMM |
250:
FKQSTFKKTY | IGEIFTQILV | LPYVGKELNM | IIMLPDETTD | LRTVEKELTY |
300:
EKFVEWTRLD | MMDEEEVEVS | LPRFKLEESY | DMESVLRNLG | MTDAFELGKA |
350:
DFSGMSQTDL | SLSKVVHKSF | VEVNEEGTEA | AAATAAIMMM | RCARFVPRFC |
376:
ADHPFLFFIQ | HSKTNGILFC | GRFSSP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Human Serpin B6
ELISA Kit for Human Serpin B6
ELISA Kit for Human Serpin B6
CLIA Kit for Human Serpin B6
CLIA Kit for Human Serpin B6
CLIA Kit for Human Serpin B6
Polyclonal Antibody for Human Serpin B6
Polyclonal Antibody for Human Serpin B6
Polyclonal Antibody for Human Serpin B6
Monoclonal Antibody for Human Serpin B6
Monoclonal Antibody for Human Serpin B6
Monoclonal Antibody for Human Serpin B6
Protein for Human Serpin B6
Protein for Human Serpin B6
Protein for Human Serpin B6
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT VAL-90
tissue :
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT VAL-90
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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Chondrosarcoma .
tissue :
Colon .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-372
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Leukemia .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY;COMPLEX FORMATION WITH BETA-TRYPTASE
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN DFNB91;FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]