SEPSECS ELISA Kit for Human(Homo sapiens) | EIAab.comSEPSECS ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SEPSECS(Gene name) > Human

SEPSECS (Gene name),

O-phosphoseryl-tRNA(Sec) selenium transferase (Protein name ), SPCS_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SEPSECS(TRNP48);

Protein name:

O-phosphoseryl-tRNA(Sec) selenium transferase;

Alternative:

SLA-p35;Liver-pancreas antigen(LP);Selenocysteine synthase(Sec synthase);SLA/LP autoantigen;Sep-tRNA:Sec-tRNA synthase(SepSecS);Selenocysteinyl-tRNA(Sec) synthase;UGA suppressor tRNA-associated protein;Soluble liver antigen(SLA);tRNA(Ser/Sec)-associated antigenic protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

501

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

501:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9HD40

MIM:

613009

KEGG:

hsa:51091

Pfam:

PF05889

SMR:

Q9HD40

STRING:

9606.ENSP00000305956

UniGene:

Hs.253305

Uniprot:

Q9HD40

FOR

ELISA Kit for Human O-phosphoseryl-tRNA(Sec) selenium transferase

Cat.:

E1045m

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Manual:

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Packing:

96T

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ELISA Kit for Human O-phosphoseryl-tRNA(Sec) selenium transferase

Cat.:

E1045h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human O-phosphoseryl-tRNA(Sec) selenium transferase

Cat.:

U1045m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human O-phosphoseryl-tRNA(Sec) selenium transferase

Cat.:

U1045h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human O-phosphoseryl-tRNA(Sec) selenium transferase

Cat.:

P1045Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human O-phosphoseryl-tRNA(Sec) selenium transferase

Cat.:

P1045Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human O-phosphoseryl-tRNA(Sec) selenium transferase

Protein for Human O-phosphoseryl-tRNA(Sec) selenium transferase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Testis.
2.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Endometrium.
3.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
tissue: Brain.
tissue: Muscle.
6.

"Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis."
Wies I. , Brunner S. , Henninger J. , Herkel J. , Kanzler S. , Meyer zum Bueschenfelde K.-H. , Lohse A.W.
Lancet355:1510-1515(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 29-501 (ISOFORM 1);NUCLEOTIDE SEQUENCE [MRNA] OF 29-501 (ISOFORM 2)
tissue: Liver.
tissue: T-cell lymphoma.
7.

"Isolation and characterization of cDNA encoding the antigenic protein of the human tRNP(Ser)Sec complex recognized by autoantibodies from patients withtype-1 autoimmune hepatitis."
Costa M. , Rodriguez-Sanchez J.L. , Czaja A.J. , Gelpi C.
Clin. Exp. Immunol.121:364-374(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 61-501 (ISOFORM 1)
tissue: Liver.
8.

"Coding sequence of the human SLA/LP autoantigen."
Seelig H.-P. , Wiemann C. , Plaikner M. , Schranz P. , Seelig R. , Renz M.
Submitted (2000-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 61-501 (ISOFORM 1)
tissue: Liver.
9.

"Soluble liver antigen: isolation of a 35-kd recombinant protein (SLA-p35) specifically recognizing sera from patients with autoimmune hepatitis."
Volkmann M. , Martin L. , Baeurle A. , Heid H. , Strassburg C.P. , Trautwein C. , Fiehn W. , Manns M.P.
Hepatology33:591-596(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 208-501
10.

"Fine specificity of autoantibodies to soluble liver antigen and liver/pancreas."
Herkel J. , Heidrich B. , Nieraad N. , Wies I. , Rother M. , Lohse A.W.
Hepatology35:403-408(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 434-493;SLA/LP EPITOPE MAPPING
11.

"RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea."
Yuan J. , Palioura S. , Salazar J.C. , Su D. , O'Donoghue P. , Hohn M.J. , Cardoso A.M. , Whitman W.B. , Soell D.
Proc. Natl. Acad. Sci. U.S.A.103:18923-18927(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;COFACTOR;MUTAGENESIS OF LYS-284
12.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation."
Palioura S. , Sherrer R.L. , Steitz T.A. , Soll D. , Simonovic M.
Science325:321-325(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.81 ANGSTROMS) IN COMPLEX WITH TRNA AND PYRIDOXAL PHOSPHATE;SUBUNIT;SUBSTRATE-BINDING SITES;COFACTOR;MUTAGENESIS OF ARG-75; ARG-97; GLN-105; LYS-173 AND ARG-313
14.

"Mutations disrupting selenocysteine formation cause progressive cerebello-cerebral atrophy."
Agamy O. , Ben Zeev B. , Lev D. , Marcus B. , Fine D. , Su D. , Narkis G. , Ofir R. , Hoffmann C. , Leshinsky-Silver E. , Flusser H. , Sivan S. , Soll D. , Lerman-Sagie T. , Birk O.S.
Am. J. Hum. Genet.87:538-544(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PCH2D THR-239 AND CYS-334;CHARACTERIZATION OF VARIANTS PCH2D THR-239 AND CYS-334

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