Gene name:
AGXT (AGT1;SPAT) ;
Protein name:
Serine--pyruvate aminotransferase (SPT) ;
Alternative:
2.6.1.44;Alanine--glyoxylate aminotransferase (AGT) ;
Organism:
Human (Homo sapiens).
General Annotation
Subcellular Location:
Peroxisome
Mitochondrion matrix
Except in some HP1 patients where AGT is found in the mitochondrial matrix.
Protein Attributes:
50:
MASHKLLVTP | PKALLKPLSI | PNQLLLGPGP | SNLPPRIMAA | GGLQMIGSMS |
100:
KDMYQIMDEI | KEGIQYVFQT | RNPLTLVISG | SGHCALEAAL | VNVLEPGDSF |
150:
LVGANGIWGQ | RAVDIGERIG | ARVHPMTKDP | GGHYTLQEVE | EGLAQHKPVL |
200:
LFLTHGESST | GVLQPLDGFG | ELCHRYKCLL | LVDSVASLGG | TPLYMDRQGI |
250:
DILYSGSQKA | LNAPPGTSLI | SFSDKAKKKM | YSRKTKPFSF | YLDIKWLANF |
300:
WGCDDQPRMY | HHTIPVISLY | SLRESLALIA | EQGLENSWRQ | HREAAAYLHG |
350:
RLQALGLQLF | VKDPALRLPT | VTTVAVPAGY | DWRDIVSYVI | DHFDIEIMGG |
392:
LGPSTGKVLR | IGLLGCNATR | ENVDRVTEAL | RAALQHCPKK | KL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Rabbit
Human
Polyclonal Antibody for Human SPT
Polyclonal Antibody for Human SPT
Polyclonal Antibody for Human SPT
Polyclonal Antibody for Human SPT
Monoclonal Antibody for Human SPT
Monoclonal Antibody for Human SPT
Monoclonal Antibody for Human SPT
Monoclonal Antibody for Human SPT
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANTS LEU-11 AND MET-340;VARIANT HP1 ARG-170
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
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more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Liver .
6.
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W.
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Nature434:724-731(2005)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
Mural R.J.
,
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) IN COMPLEX WITH PYRIDOXAL PHOSPHATE AND AMINO-OXYACETIC ACID;SUBUNIT;PYRIDOXAL PHOSPHATE AT LYS-209
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT HP1 PRO-205
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT HP1 GLU-82
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT HP1 PHE-187
13.
"Enzymological and mutational analysis of a complex primary hyperoxaluria type 1 phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation."
Danpure C.J.
,
Purdue P.E.
,
Fryer P.
,
Griffiths S.
,
Allsop J.
,
Lumb M.J.
,
Guttridge K.M.
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Jennings P.R.
,
Scheinman J.I.
,
Mauer S.M.
,
Davidson N.O.
Am. J. Hum. Genet.53:417-432(1993)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 ARG-41 AND ILE-152
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON HP1
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 CYS-233; HIS-233 AND THR-244
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 ARG-108; TYR-173; ARG-190; ALA-296 DEL AND ASP-350
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 VAL-41; GLU-95 INS; ARG-116 AND ARG-156
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 VAL-41; GLU-95 INS; ARG-116 AND ARG-156
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 ARG-41; ARG-156; ARG-190; THR-244; CYS-289 AND PRO-298
20.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 ILE-152; ARG-170; ASN-183; CYS-233 AND THR-244
21.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION OF VARIANTS HP1 ARG-41; GLU-82; ILE-152; ARG-170 AND THR-244;CHARACTERIZATION OF VARIANT LEU-11;MUTAGENESIS OF LYS-209
22.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT HP1 ASP-112;VARIANT ILE-326
23.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION OF VARIANT HP1 THR-244
24.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 ARG-82; ILE-152; VAL-153; ARG-170 AND ASP-336
25.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS HP1 ASN-9; VAL-139 DEL; ARG-156; LEU-158; ARG-190; GLU-201; LEU-233; THR-244 AND ARG-253
26.
"Intra-familial clinical heterogeneity: absence of genotype-phenotype correlation in primary hyperoxaluria type 1 in Israel."
Frishberg Y.
,
Rinat C.
,
Shalata A.
,
Khatib I.
,
Feinstein S.
,
Becker-Cohen R.
,
Weismann I.
,
Wanders R.J.A.
,
Rumsby G.
,
Roels F.
,
Mandel H.
Am. J. Nephrol.25:269-275(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : VARIANTS HP1 ASN-9; ARG-41; ARG-108; ARG-156; ARG-190; ARG-195; HIS-243; THR-244; MET-279; THR-287; CYS-289 AND PRO-298
27.
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Cited for : VARIANTS HP1 ARG-161 AND LEU-218;VARIANTS THR-279 AND VAL-280