SRY ELISA Kit for Human(Homo sapiens) | EIAab.comSRY ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SRY(Gene name) > Human

SRY (Gene name),

Sex-determining region Y protein (Protein name ), SRY_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SRY(TDF);

Protein name:

Sex-determining region Y protein;

Alternative:

Testis-determining factor;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with CALM, EP300, HDAC3, KPNB1, ZNF208 isoform KRAB-O, PARP1, SLC9A3R2 and WT1. The interaction with EP300 modulates its DNA-binding activity. The interaction with KPNB1 is sensitive to dissociation by Ran in the GTP-bound form (By similarity). Interaction with PARP1 impaired its DNA-binding activity.

Function:

Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.

Subcellular Location:

Nucleus speckle Cytoplasm Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus. Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH).

Protein Attributes:

Sequence length:

204

Sequence:

50:

100:

150:

200:

204:

WTKL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00505

MIM:

400044

UniGene:

Hs.1992

STRING:

9606.ENSP00000372547

SMR:

Q05066

KEGG:

hsa:6736

String:

Q05066

Uniprot:

Q05066

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ELISA Kit for Human Sex-determining region Y protein

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E8883h

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96T

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ELISA Kit for Human Sex-determining region Y protein

Cat.:

E8883d

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ELISA Kit for Human Sex-determining region Y protein

Cat.:

E8883m

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96T

ELISA Kit for Human Sex-determining region Y protein

Cat.:

E8883r

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96T

ELISA Kit for Human Sex-determining region Y protein

Cat.:

E8883p

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96T

ELISA Kit for Human Sex-determining region Y protein

Cat.:

E8883b

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96T

CLIA Kit for Human Sex-determining region Y protein

Cat.:

U8883p

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Packing:

96T

CLIA Kit for Human Sex-determining region Y protein

Cat.:

U8883m

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MSDS:

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Packing:

96T

CLIA Kit for Human Sex-determining region Y protein

Cat.:

U8883r

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96T

CLIA Kit for Human Sex-determining region Y protein

Cat.:

U8883b

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96T

CLIA Kit for Human Sex-determining region Y protein

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CLIA Kit for Human Sex-determining region Y protein

Cat.:

U8883h

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96T

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Polyclonal Antibody for Human Sex-determining region Y protein

Cat.:

P8883Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Sex-determining region Y protein

Cat.:

P8883Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Sex-determining region Y protein

Monoclonal Antibody for Human Sex-determining region Y protein

Protein for Human Sex-determining region Y protein