SSTR2 ELISA Kit for Human(Homo sapiens) | EIAab.comSSTR2 ELISA Kit for Human(Homo sapiens)

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SSTR2 (Gene name),

Somatostatin receptor type 2 (Protein name ), SSR2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SSTR2;

Protein name:

Somatostatin receptor type 2(SS-2-R;SS2-R;SS2R);

Alternative:

SRIF-1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

The C-terminus interacts with SHANK1 PDZ domain.

Function:

Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

369

Sequence:

50:

100:

150:

200:

250:

300:

350:

369:

NETTETQRTL | LNGDLQTSI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.514451

Pfam:

PF00001

KEGG:

hsa:6752

MIM:

182452

SMR:

P30874

String:

P30874

STRING:

9606.ENSP00000350198

Uniprot:

P30874

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ELISA Kit for Human SS-2-R

Cat.:

E2292h

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96T

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ELISA Kit for Human SS-2-R

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E2292m

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96T

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ELISA Kit for Human SS-2-R

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E2292r

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ELISA Kit for Human SS-2-R

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E2292p

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96T

ELISA Kit for Human SS-2-R

Cat.:

E2292d

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96T

ELISA Kit for Human SS-2-R

Cat.:

E2292b

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96T

CLIA Kit for Human SS-2-R

Cat.:

U2292b

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96T

CLIA Kit for Human SS-2-R

Cat.:

U2292d

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96T

CLIA Kit for Human SS-2-R

Cat.:

U2292m

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Packing:

96T

CLIA Kit for Human SS-2-R

Cat.:

U2292r

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MSDS:

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Packing:

96T

CLIA Kit for Human SS-2-R

Cat.:

U2292p

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MSDS:

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Packing:

96T

CLIA Kit for Human SS-2-R

Cat.:

U2292h

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96T

Polyclonal Antibody for Human SS-2-R

Cat.:

P2292Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human SS-2-R

Cat.:

P2292Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human SS-2-R

Cat.:

P2292Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human SS-2-R

Monoclonal Antibody for Human SS-2-R

Protein for Human SS-2-R

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney."
Yamada Y. , Post S.R. , Wang K. , Tager H.S. , Bell G.I. , Seino S.
Proc. Natl. Acad. Sci. U.S.A.89:251-255(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM A)
2.

"Genomic structure and transcriptional regulation of the human somatostatin receptor type 2."
Petersenn S. , Rasch A.C. , Presch S. , Beil F.U. , Schulte H.M.
Mol. Cell. Endocrinol.157:75-85(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS A AND B)
3.

"Isolation of complete coding sequence for somatostatin receptor 2 (SSTR2)."
Kopatz S.A. , Aronstam R.S. , Sharma S.V.
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Genome-wide discovery and analysis of human seven transmembrane helix receptor genes."
Suwa M. , Sato T. , Okouchi I. , Arita M. , Futami K. , Matsumoto S. , Tsutsumi S. , Aburatani H. , Asai K. , Akiyama Y.
Submitted (2001-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A)
6.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A)
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A)
tissue: Eye.
8.

"Multiple gene transcripts of the somatostatin receptor SSTR2: tissue selective distribution and cAMP regulation."
Patel Y.C. , Greenwood M. , Kent G. , Panetta R. , Srikant C.B.
Biochem. Biophys. Res. Commun.192:288-294(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS A AND B)
9.

"Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain."
Zitzer H. , Hoenck H.-H. , Baechner D. , Richter D. , Kreienkamp H.-J.
J. Biol. Chem.274:32997-33001(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SHANK1
10.

"Agonist-dependent dissociation of human somatostatin receptor 2 dimers: a role in receptor trafficking."
Grant M. , Collier B. , Kumar U.
J. Biol. Chem.279:36179-36183(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION
11.

"Cell growth inhibition and functioning of human somatostatin receptor type 2 are modulated by receptor heterodimerization."
Grant M. , Alturaihi H. , Jaquet P. , Collier B. , Kumar U.
Mol. Endocrinol.22:2278-2292(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;INTERACTION WITH BETA-ARRESTIN;SUBCELLULAR LOCATION
12.

"The somatostatin 2A receptor is enriched in migrating neurons during rat and human brain development and stimulates migration and axonal outgrowth."
Le Verche V. , Kaindl A.M. , Verney C. , Csaba Z. , Peineau S. , Olivier P. , Adle-Biassette H. , Leterrier C. , Vitalis T. , Renaud J. , Dargent B. , Gressens P. , Dournaud P.
PLoS ONE4:E5509-E5509(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
13.

"SSTR2 is the functionally dominant somatostatin receptor in human pancreatic beta- and alpha-cells."
Kailey B. , van de Bunt M. , Cheley S. , Johnson P.R. , MacDonald P.E. , Gloyn A.L. , Rorsman P. , Braun M.
Am. J. Physiol.303:E1107-E1116(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
14.

"Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2."
Parry J.J. , Chen R. , Andrews R. , Lears K.A. , Rogers B.E.
Endocrinology153:2747-2755(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF ASP-89; ASP-139 AND ARG-140

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