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Index > Protein center > STAB1(Gene name) > Human
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  • STAB1 (Gene name),
  • Stabilin-1 (Protein name ),  STAB1_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    STAB1(FEEL1;KIAA0246);
    Protein name:
    Stabilin-1;
    Alternative:
    MS-1 antigen;Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1(FEEL-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CHID1.
    Function:
    Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    2570
    Sequence:
    50:
    MAGPRGLLPL | CLLAFCLAGF | SFVRGQVLFK | GCDVKTTFVT | HVPCTSCAAI | 
    100:
    KKQTCPSGWL | RELPDQITQD | CRYEVQLGGS | MVSMSGCRRK | CRKQVVQKAC | 
    150:
    CPGYWGSRCH | ECPGGAETPC | NGHGTCLDGM | DRNGTCVCQE | NFRGSACQEC | 
    200:
    QDPNRFGPDC | QSVCSCVHGV | CNHGPRGDGS | CLCFAGYTGP | HCDQELPVCQ | 
    250:
    ELRCPQNTQC | SAEAPSCRCL | PGYTQQGSEC | RAPNPCWPSP | CSLLAQCSVS | 
    300:
    PKGQAQCHCP | ENYHGDGMVC | LPKDPCTDNL | GGCPSNSTLC | VYQKPGQAFC | 
    350:
    TCRPGLVSIN | SNASAGCFAF | CSPFSCDRSA | TCQVTADGKT | SCVCRESEVG | 
    400:
    DGRACYGHLL | HEVQKATQTG | RVFLQLRVAV | AMMDQGCREI | LTTAGPFTVL | 
    450:
    VPSVSSFSSR | TMNASLAQQL | CRQHIIAGQH | ILEDTRTQQT | RRWWTLAGQE | 
    500:
    ITVTFNQFTK | YSYKYKDQPQ | QTFNIYKANN | IAANGVFHVV | TGLRWQAPSG | 
    550:
    TPGDPKRTIG | QILASTEAFS | RFETILENCG | LPSILDGPGP | FTVFAPSNEA | 
    600:
    VDSLRDGRLI | YLFTAGLSKL | QELVRYHIYN | HGQLTVEKLI | SKGRILTMAN | 
    650:
    QVLAVNISEE | GRILLGPEGV | PLQRVDVMAA | NGVIHMLDGI | LLPPTILPIL | 
    700:
    PKHCSEEQHK | IVAGSCVDCQ | ALNTSTCPPN | SVKLDIFPKE | CVYIHDPTGL | 
    750:
    NVLKKGCASY | CNQTIMEQGC | CKGFFGPDCT | QCPGGFSNPC | YGKGNCSDGI | 
    800:
    QGNGACLCFP | DYKGIACHIC | SNPNKHGEQC | QEDCGCVHGL | CDNRPGSGGV | 
    850:
    CQQGTCAPGF | SGRFCNESMG | DCGPTGLAQH | CHLHARCVSQ | EGVARCRCLD | 
    900:
    GFEGDGFSCT | PSNPCSHPDR | GGCSENAECV | PGSLGTHHCT | CHKGWSGDGR | 
    950:
    VCVAIDECEL | DMRGGCHTDA | LCSYVGPGQS | RCTCKLGFAG | DGYQCSPIDP | 
    1000:
    CRAGNGGCHG | LATCRAVGGG | QRVCTCPPGF | GGDGFSCYGD | IFRELEANAH | 
    1050:
    FSIFYQWLKS | AGITLPADRR | VTALVPSEAA | VRQLSPEDRA | FWLQPRTLPN | 
    1100:
    LVRAHFLQGA | LFEEELARLG | GQEVATLNPT | TRWEIRNISG | RVWVQNASVD | 
    1150:
    VADLLATNGV | LHILSQVLLP | PRGDVPGGQG | LLQQLDLVPA | FSLFRELLQH | 
    1200:
    HGLVPQIEAA | TAYTIFVPTN | RSLEAQGNSS | HLDADTVRHH | VVLGEALSME | 
    1250:
    TLRKGGHRNS | LLGPAHWIVF | YNHSGQPEVN | HVPLEGPMLE | APGRSLIGLS | 
    1300:
    GVLTVGSSRC | LHSHAEALRE | KCVNCTRRFR | CTQGFQLQDT | PRKSCVYRSG | 
    1350:
    FSFSRGCSYT | CAKKIQVPDC | CPGFFGTLCE | PCPGGLGGVC | SGHGQCQDRF | 
    1400:
    LGSGECHCHE | GFHGTACEVC | ELGRYGPNCT | GVCDCAHGLC | QEGLQGDGSC | 
    1450:
    VCNVGWQGLR | CDQKITSPQC | PRKCDPNANC | VQDSAGASTC | ACAAGYSGNG | 
    1500:
    IFCSEVDPCA | HGHGGCSPHA | NCTKVAPGQR | TCTCQDGYMG | DGELCQEINS | 
    1550:
    CLIHHGGCHI | HAECIPTGPQ | QVSCSCREGY | SGDGIRTCEL | LDPCSKNNGG | 
    1600:
    CSPYATCKST | GDGQRTCTCD | TAHTVGDGLT | CRARVGLELL | RDKHASFFSL | 
    1650:
    RLLEYKELKG | DGPFTIFVPH | ADLMSNLSQD | ELARIRAHRQ | LVFRYHVVGC | 
    1700:
    RRLRSEDLLE | QGYATALSGH | PLRFSEREGS | IYLNDFARVV | SSDHEAVNGI | 
    1750:
    LHFIDRVLLP | PEALHWEPDD | APIPRRNVTA | AAQGFGYKIF | SGLLKVAGLL | 
    1800:
    PLLREASHRP | FTMLWPTDAA | FRALPPDRQA | WLYHEDHRDK | LAAILRGHMI | 
    1850:
    RNVEALASDL | PNLGPLRTMH | GTPISFSCSR | TRAGELMVGE | DDARIVQRHL | 
    1900:
    PFEGGLAYGI | DQLLEPPGLG | ARCDHFETRP | LRLNTCSICG | LEPPCPEGSQ | 
    1950:
    EQGSPEACWR | FYPKFWTSPP | LHSLGLRSVW | VHPSLWGRPQ | GLGRGCHRNC | 
    2000:
    VTTTWKPSCC | PGHYGSECQA | CPGGPSSPCS | DRGVCMDGMS | GSGQCLCRSG | 
    2050:
    FAGTACELCA | PGAFGPHCQA | CRCTVHGRCD | EGLGGSGSCF | CDEGWTGPRC | 
    2100:
    EVQLELQPVC | TPPCAPEAVC | RAGNSCECSL | GYEGDGRVCT | VADLCQDGHG | 
    2150:
    GCSEHANCSQ | VGTMVTCTCL | PDYEGDGWSC | RARNPCTDGH | RGGCSEHANC | 
    2200:
    LSTGLNTRRC | ECHAGYVGDG | LQCLEESEPP | VDRCLGQPPP | CHSDAMCTDL | 
    2250:
    HFQEKRAGVF | HLQATSGPYG | LNFSEAEAAC | EAQGAVLASF | PQLSAAQQLG | 
    2300:
    FHLCLMGWLA | NGSTAHPVVF | PVADCGNGRV | GIVSLGARKN | LSERWDAYCF | 
    2350:
    RVQDVACRCR | NGFVGDGIST | CNGKLLDVLA | ATANFSTFYG | MLLGYANATQ | 
    2400:
    RGLDFLDFLD | DELTYKTLFV | PVNEGFVDNM | TLSGPDLELH | ASNATLLSAN | 
    2450:
    ASQGKLLPAH | SGLSLIISDA | GPDNSSWAPV | APGTVVVSRI | IVWDIMAFNG | 
    2500:
    IIHALASPLL | APPQPQAVLA | PEAPPVAAGV | GAVLAAGALL | GLVAGALYLR | 
    2550:
    ARGKPMGFGF | SAFQAEDDAD | DDFSPWQEGT | NPTLVSVPNP | VFGSDTFCEP | 
    2570:
    FDDSLLEEDF | PDTQRILTVK | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Pfam:
    MIM:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Stabilin-1
    Cat.:
    E1417h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Stabilin-1
    Cat.:
    E1417m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Stabilin-1
    Cat.:
    U1417h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Stabilin-1
    Cat.:
    U1417m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Stabilin-1
    Cat.:
    P1417Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Stabilin-1
    Cat.:
    P1417Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Stabilin-1
    Monoclonal Antibody for Human Stabilin-1
    Protein for Human Stabilin-1
    Protein for Human Stabilin-1

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues."
      Politz O. , Gratchev A. , McCourt P.A.G. , Schledzewski K. , Guillot P. , Johansson S. , Svineng G. , Franke P. , Kannicht C. , Kzhyshkowska J. , Longati P. , Velten F.W. , Johansson S. , Goerdt S.
      Biochem. J.362:155-164(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;VARIANTS VARIANTS VAL-912; PRO-1833 AND VAL-2282
    2. 2.
      "FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities."
      Adachi H. , Tsujimoto M.
      J. Biol. Chem.277:34264-34270(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;TISSUE SPECIFICITY;VARIANT VAL-912
    3. 3.
      "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."
      Nagase T. , Seki N. , Ishikawa K. , Ohira M. , Kawarabayasi Y. , Ohara O. , Tanaka A. , Kotani H. , Miyajima N. , Nomura N.
      DNA Res.3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS VAL-912 AND PRO-1833
      tissue: Brain.
    4. 4.
      "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
      DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    5. 5.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS VAL-912 AND PRO-1833
    7. 7.
      "Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway."
      Kzhyshkowska J. , Mamidi S. , Gratchev A. , Kremmer E. , Schmuttermaier C. , Krusell L. , Haus G. , Utikal J. , Schledzewski K. , Scholtze J. , Goerdt S.
      Blood107:3221-3228(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CHID1
    8. 8.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1096; ASN-1626; ASN-1727; ASN-2347 AND ASN-2424
      tissue: Liver.
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