STAT4 ELISA Kit for Human(Homo sapiens) | EIAab.comSTAT4 ELISA Kit for Human(Homo sapiens)

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STAT4 (Gene name),

Signal transducer and activator of transcription 4 (Protein name ), STAT4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

STAT4;

Protein name:

Signal transducer and activator of transcription 4;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Forms a homodimer or a heterodimer with a related family member. Interacts with ARL2BP (By similarity). The SH2 domain interacts, in vitro, with IL12RB2 via a short cytoplasmic domain.

Function:

Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.

Subcellular Location:

Cytoplasm Nucleus Translocated into the nucleus in response to phosphorylation.

Protein Attributes:

Sequence length:

748

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

748:

ISTIRSDSTE | PHSPSDLLPM | SPSVYAVLRE | NLSPTTIETA | MKSPYSAE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

180300

UniGene:

Hs.80642

String:

Q14765

UniGene:

Hs.735572

Pfam:

PF00017

KEGG:

hsa:6775

SMR:

Q14765

STRING:

9606.ENSP00000351255

Uniprot:

Q14765

FOR

ELISA Kit for Human Signal transducer and activator of transcription 4

Cat.:

E1739h

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human Signal transducer and activator of transcription 4

Cat.:

E1739m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Signal transducer and activator of transcription 4

Cat.:

U1739h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Signal transducer and activator of transcription 4

Cat.:

U1739m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Signal transducer and activator of transcription 4

Cat.:

P1739Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Signal transducer and activator of transcription 4

Cat.:

P1739Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Signal transducer and activator of transcription 4

Protein for Human Signal transducer and activator of transcription 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The STAT amino-terminal domain mediates cooperative DNA binding and confers selective sequence recognition."
Xu X. , Sun Y.L. , Hoey T.
Submitted (1996-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.
3.

SeattleSNPs variation discovery resource
Submitted (2001-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 91-748
4.

"Direct interaction of STAT4 with the IL-12 receptor."
Yao B.B. , Niu P. , Surowy C.S. , Faltynek C.R.
Arch. Biochem. Biophys.368:147-155(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IL12RB2
5.

"Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling."
Naeger L.K. , McKinney J. , Salvekar A. , Hoey T.
J. Biol. Chem.274:1875-1878(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IL12RB2
6.

"Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo."
Kariuki S.N. , Kirou K.A. , MacDermott E.J. , Barillas-Arias L. , Crow M.K. , Niewold T.B.
J. Immunol.182:34-38(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SLEB11
7.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] GLN-112
8.

"STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus."
Remmers E.F. , Plenge R.M. , Lee A.T. , Graham R.R. , Hom G. , Behrens T.W. , de Bakker P.I.W. , Le J.M. , Lee H.-S. , Batliwalla F. , Li W. , Masters S.L. , Booty M.G. , Carulli J.P. , Padyukov L. , Alfredsson L. , Klareskog L. , Chen W.V. , more...
N. Engl. J. Med.357:977-986(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SLEB11 AND RA

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