Gene name:
TBC1D1 (KIAA1108) ;
Protein name:
TBC1 domain family member 1 ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Function:
May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MEPITFTARK | HLLSNEVSVD | FGLQLVGSLP | VHSLTTMPML | PWVVAEVRRL |
100:
SRQSTRKEPV | TKQVRLCVSP | SGLRCEPEPG | RSQQWDPLIY | SSIFECKPQR |
150:
VHKLIHNSHD | PSYFACLIKE | DAVHRQSICY | VFKADDQTKV | PEIISSIRQA |
200:
GKIARQEELH | CPSEFDDTFS | KKFEVLFCGR | VTVAHKKAPP | ALIDECIEKF |
250:
NHVSGSRGSE | SPRPNPPHAA | PTGSQEPVRR | PMRKSFSQPG | LRSLAFRKEL |
300:
QDGGLRSSGF | FSSFEESDIE | NHLISGHNIV | QPTDIEENRT | MLFTIGQSEV |
350:
YLISPDTKKI | ALEKNFKEIS | FCSQGIRHVD | HFGFICRESS | GGGGFHFVCY |
400:
VFQCTNEALV | DEIMMTLKQA | FTVAAVQQTA | KAPAQLCEGC | PLQSLHKLCE |
450:
RIEGMNSSKT | KLELQKHLTT | LTNQEQATIF | EEVQKLRPRN | EQRENELIIS |
500:
FLRCLYEEKQ | KEHIHIGEMK | QTSQMAAENI | GSELPPSATR | FRLDMLKNKA |
550:
KRSLTESLES | ILSRGNKARG | LQEHSISVDL | DSSLSSTLSN | TSKEPSVCEK |
600:
EALPISESSF | KLLGSSEDLS | SDSESHLPEE | PAPLSPQQAF | RRRANTLSHF |
650:
PIECQEPPQP | ARGSPGVSQR | KLMRYHSVST | ETPHERKDFE | SKANHLGDSG |
700:
GTPVKTRRHS | WRQQIFLRVA | TPQKACDSSS | RYEDYSELGE | LPPRSPLEPV |
750:
CEDGPFGPPP | EEKKRTSREL | RELWQKAILQ | QILLLRMEKE | NQKLQASEND |
800:
LLNKRLKLDY | EEITPCLKEV | TTVWEKMLST | PGRSKIKFDM | EKMHSAVGQG |
850:
VPRHHRGEIW | KFLAEQFHLK | HQFPSKQQPK | DVPYKELLKQ | LTSQQHAILI |
900:
DLGRTFPTHP | YFSAQLGAGQ | LSLYNILKAY | SLLDQEVGYC | QGLSFVAGIL |
950:
LLHMSEEEAF | KMLKFLMFDM | GLRKQYRPDM | IILQIQMYQL | SRLLHDYHRD |
1000:
LYNHLEEHEI | GPSLYAAPWF | LTMFASQFPL | GFVARVFDMI | FLQGTEVIFK |
1050:
VALSLLGSHK | PLILQHENLE | TIVDFIKSTL | PNLGLVQMEK | TINQVFEMDI |
1100:
AKQLQAYEVE | YHVLQEELID | SSPLSDNQRM | DKLEKTNSSL | RKQNLDLLEQ |
1150:
LQVANGRIQS | LEATIEKLLS | SESKLKQAML | TLELERSALL | QTVEELRRRS |
1168:
AEPSDREPEC | TQPEPTGD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
ELISA Kit for Human TBC1 domain family member 1
ELISA Kit for Human TBC1 domain family member 1
ELISA Kit for Human TBC1 domain family member 1
CLIA Kit for Human TBC1 domain family member 1
CLIA Kit for Human TBC1 domain family member 1
CLIA Kit for Human TBC1 domain family member 1
Polyclonal Antibody for Human TBC1 domain family member 1
Polyclonal Antibody for Human TBC1 domain family member 1
Polyclonal Antibody for Human TBC1 domain family member 1
Monoclonal Antibody for Human TBC1 domain family member 1
Monoclonal Antibody for Human TBC1 domain family member 1
Monoclonal Antibody for Human TBC1 domain family member 1
Protein for Human TBC1 domain family member 1
Protein for Human TBC1 domain family member 1
Protein for Human TBC1 domain family member 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 482-1168 (ISOFORM 1);VARIANT PRO-14
tissue :
Embryo .
tissue :
Hippocampus .
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[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 406-1168 (ISOFORM 1)
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-507; SER-565; SER-570; SER-573 AND SER-585;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 750-1072;MUTAGENESIS OF MET-930 AND LEU-1019
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"TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition."
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[
PubMed ]
[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT TRP-125
10.
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT TRP-125