Gene name:
TBX21 (TBET;TBLYM) ;
Protein name:
T-box transcription factor TBX21 (T-box protein 21) ;
Alternative:
Transcription factor TBLYM ;T-cell-specific T-box transcription factor T-bet ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MGIVEPGCGD | MLTGTEPMPG | SDEGRAPGAD | PQHRYFYPEP | GAQDADERRG |
100:
GGSLGSPYPG | GALVPAPPSR | FLGAYAYPPR | PQAAGFPGAG | ESFPPPADAE |
150:
GYQPGEGYAA | PDPRAGLYPG | PREDYALPAG | LEVSGKLRVA | LNNHLLWSKF |
200:
NQHQTEMIIT | KQGRRMFPFL | SFTVAGLEPT | SHYRMFVDVV | LVDQHHWRYQ |
250:
SGKWVQCGKA | EGSMPGNRLY | VHPDSPNTGA | HWMRQEVSFG | KLKLTNNKGA |
300:
SNNVTQMIVL | QSLHKYQPRL | HIVEVNDGEP | EAACNASNTH | IFTFQETQFI |
350:
AVTAYQNAEI | TQLKIDNNPF | AKGFRENFES | MYTSVDTSIP | SPPGPNCQFL |
400:
GGDHYSPLLP | NQYPVPSRFY | PDLPGQAKDV | VPQAYWLGAP | RDHSYEAEFR |
450:
AVSMKPAFLP | SAPGPTMSYY | RGQEVLAPGA | GWPVAPQYPP | KMGPASWFRP |
500:
MRTLPMEPGP | GGSEGRGPED | QGPPLVWTEI | APIRPESSDS | GLGEGDSKRR |
535:
RVSPYPSSGD | SSSPAGAPSP | FDKEAEGQFY | NYFPN
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human T-box protein 21
ELISA Kit for Human T-box protein 21
CLIA Kit for Human T-box protein 21
CLIA Kit for Human T-box protein 21
Polyclonal Antibody for Human T-box protein 21
Polyclonal Antibody for Human T-box protein 21
Monoclonal Antibody for Human T-box protein 21
Monoclonal Antibody for Human T-box protein 21
Protein for Human T-box protein 21
Protein for Human T-box protein 21
R&D Technical Data
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
"Cloning and characterization of a new member of T-box gene family."
Yang S.
Submitted (1998-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .
4.
"Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma."
Akahoshi M.
,
Obara K.
,
Hirota T.
,
Matsuda A.
,
Hasegawa K.
,
Takahashi N.
,
Shimizu M.
,
Nakashima K.
,
Cheng L.
,
Doi S.
,
Fujiwara H.
,
Miyatake A.
,
Fujita K.
,
Higashi N.
,
Taniguchi M.
,
Enomoto T.
,
Mao X.-Q.
,
Nakashima H.
,
Adra C.N.
,
Nakamura Y.
,
Tamari M.
,
Shirakawa T.
more...
Hum. Genet.117:16-26(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN SUSCEPTIBILITY TO ASPIRIN-INDUCED ASTHMA;INVOLVEMENT IN SUSCEPTIBILITY TO ASTHMA AND NASAL POLYPS;VARIANT GLN-33