Protein name:
Testin ;
Alternative:
TESS ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts via LIM domain 1 with ZYX. Interacts (via LIM domain 3) with ENAH and VASP. Interacts with talin, actin, alpha-actinin, GRIP1 and PXN. Interacts (via LIM domain 2) with ACTL7A (via N-terminus). Heterodimer with ACTL7A; the heterodimer interacts with ENAH to form a heterotrimer.
Function:
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.
Subcellular Location:
Cytoplasm
Cell junction
focal adhesion
Detected along actin stress fibers.
Protein Attributes:
50:
MDLENKVKKM | GLGHEQGFGA | PCLKCKEKCE | GFELHFWRKI | CRNCKCGQEE |
100:
HDVLLSNEED | RKVGKLFEDT | KYTTLIAKLK | SDGIPMYKRN | VMILTNPVAA |
150:
KKNVSINTVT | YEWAPPVQNQ | ALARQYMQML | PKEKQPVAGS | EGAQYRKKQL |
200:
AKQLPAHDQD | PSKCHELSPR | EVKEMEQFVK | KYKSEALGVG | DVKLPCEMDA |
250:
QGPKQMNIPG | GDRSTPAAVG | AMEDKSAEHK | RTQYSCYCCK | LSMKEGDPAI |
300:
YAERAGYDKL | WHPACFVCST | CHELLVDMIY | FWKNEKLYCG | RHYCDSEKPR |
350:
CAGCDELIFS | NEYTQAENQN | WHLKHFCCFD | CDSILAGEIY | VMVNDKPVCK |
400:
PCYVKNHAVV | CQGCHNAIDP | EVQRVTYNNF | SWHASTECFL | CSCCSKCLIG |
421:
QKFMPVEGMV | FCSVECKKRM | S
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Dog
Pig
Rat
Mouse
Chicken
Rabbit
ELISA Kit for Human Testin
ELISA Kit for Human Testin
ELISA Kit for Human Testin
ELISA Kit for Human Testin
ELISA Kit for Human Testin
ELISA Kit for Human Testin
ELISA Kit for Human Testin
ELISA Kit for Human Testin
CLIA Kit for Human Testin
CLIA Kit for Human Testin
CLIA Kit for Human Testin
CLIA Kit for Human Testin
CLIA Kit for Human Testin
CLIA Kit for Human Testin
CLIA Kit for Human Testin
CLIA Kit for Human Testin
Polyclonal Antibody for Human Testin
Polyclonal Antibody for Human Testin
Polyclonal Antibody for Human Testin
Polyclonal Antibody for Human Testin
Polyclonal Antibody for Human Testin
Polyclonal Antibody for Human Testin
Polyclonal Antibody for Human Testin
Polyclonal Antibody for Human Testin
Monoclonal Antibody for Human Testin
Monoclonal Antibody for Human Testin
Monoclonal Antibody for Human Testin
Monoclonal Antibody for Human Testin
Monoclonal Antibody for Human Testin
Monoclonal Antibody for Human Testin
Monoclonal Antibody for Human Testin
Monoclonal Antibody for Human Testin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
3.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
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more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Embryo .
tissue :
Prostate .
4.
"Human chromosome 7: DNA sequence and biology."
Scherer S.W.
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Science300:767-772(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
"The DNA sequence of human chromosome 7."
Hillier L.W.
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Nature424:157-164(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Placenta .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;DOMAIN;MUTAGENESIS OF CYS-391;INTERACTION WITH ENAH; ZYX; VASP; ACTIN FIBERS; ALPHA-ACTININ AND PXN
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH ZYX; GRIP1; ENAH AND TALIN;SUBCELLULAR LOCATION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ALKBH4
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 357-421 IN COMPLEX WITH ZINC IONS AND ENAH
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.62 ANGSTROMS) OF 296-421 IN COMPLEX WITH ZINC IONS; ENAH AND ACTL7A;MUTAGENESIS OF CYS-328;SUBUNIT