Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > TFCP2(Gene name) > Human
  • Add your favorite
  • TFCP2 (Gene name),
  • Alpha-globin transcription factor CP2 (Protein name ),  TFCP2_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    TFCP2(LSF;SEF);
    Protein name:
    Alpha-globin transcription factor CP2;
    Alternative:
    Transcription factor LSF;SAA3 enhancer factor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds to DNA as a dimer, isoform 3 does not bind to DNA or affect the binding of isoform 1 to DNA. Interacts with UBP1 and PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1 (By similarity). Component of the SSP (stage selector protein) complex, which appears to be a heteromer of TFCP2 and 2 copies of NFE4.
    Function:
    Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    502
    Sequence:
    50:
    MAWALKLPLA | DEVIESGLVQ | DFDASLSGIG | QELGAGAYSM | SDVLALPIFK | 
    100:
    QEESSLPPDN | ENKILPFQYV | LCAATSPAVK | LHDETLTYLN | QGQSYEIRML | 
    150:
    DNRKLGELPE | INGKLVKSIF | RVVFHDRRLQ | YTEHQQLEGW | RWNRPGDRIL | 
    200:
    DIDIPMSVGI | IDPRANPTQL | NTVEFLWDPA | KRTSVFIQVH | CISTEFTMRK | 
    250:
    HGGEKGVPFR | VQIDTFKENE | NGEYTEHLHS | ASCQIKVFKP | KGADRKQKTD | 
    300:
    REKMEKRTPH | EKEKYQPSYE | TTILTECSPW | PEITYVNNSP | SPGFNSSHSS | 
    350:
    FSLGEGNGSP | NHQPEPPPPV | TDNLLPTTTP | QEAQQWLHRN | RFSTFTRLFT | 
    400:
    NFSGADLLKL | TRDDVIQICG | PADGIRLFNA | LKGRMVRPRL | TIYVCQESLQ | 
    450:
    LREQQQQQQQ | QQQKHEDGDS | NGTFFVYHAI | YLEELTAVEL | TEKIAQLFSI | 
    500:
    SPCQISQIYK | QGPTGIHVLI | SDEMIQNFQE | EACFILDTMK | AETNDSYHII | 
    502:
    LK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    MIM:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-globin transcription factor CP2
    MSDS:
    Please sign in first.
    ELISA Kit for Human Alpha-globin transcription factor CP2
    Cat.:
    E13038h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Alpha-globin transcription factor CP2
    Cat.:
    U13038h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Alpha-globin transcription factor CP2
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human Alpha-globin transcription factor CP2
    Polyclonal Antibody for Human Alpha-globin transcription factor CP2
    Monoclonal Antibody for Human Alpha-globin transcription factor CP2
    Monoclonal Antibody for Human Alpha-globin transcription factor CP2
    Protein for Human Alpha-globin transcription factor CP2
    Protein for Human Alpha-globin transcription factor CP2

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning of the alpha-globin transcription factor CP2."
      Lim L.C. , Swendeman S.L. , Sheffery M.
      Mol. Cell. Biol.12:828-835(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4);PROTEIN SEQUENCE OF 129-140; 165-176; 348-358 AND 390-397;FUNCTION;SUBCELLULAR LOCATION
    2. 2.
      "Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro."
      Yoon J.-B. , Li G. , Roeder R.G.
      Mol. Cell. Biol.14:1776-1785(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [MRNA] OF 61-502 (ISOFORM 3);DNA-BINDING;SUBCELLULAR LOCATION;ALTERNATIVE SPLICING
    3. 3.
      "One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs."
      Shirra M.K. , Zhu Q. , Huang H.-C. , Pallas D. , Hansen U.
      Mol. Cell. Biol.14:5076-5087(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);PROTEIN SEQUENCE OF 7-21; 81-98; 149-164; 165-179; 348-359 AND 363-376;FUNCTION;ALTERNATIVE SPLICING;MUTAGENESIS OF VAL-211; ILE-213; GLN-234 AND LYS-236
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Teratocarcinoma.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Muscle.
    7. 7.
      "Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2."
      Swendeman S.L. , Spielholz C. , Jenkins N.A. , Gilbert D.J. , Copeland N.G. , Sheffery M.
      J. Biol. Chem.269:11663-11671(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    8. 8.
      "Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein."
      Jane S.M. , Nienhuis A.W. , Cunningham J.M.
      EMBO J.14:97-105(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE SSP COMPLEX;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    10. 10.
      "Purification and characterization of the serum amyloid A3 enhancer factor."
      Bing Z. , Reddy S.A. , Ren Y. , Qin J. , Liao W.S.-L.
      J. Biol. Chem.274:24649-24656(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    11. 11.
      "Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4."
      Zhou W. , Clouston D.R. , Wang X. , Cerruti L. , Cunningham J.M. , Jane S.M.
      Mol. Cell. Biol.20:7662-7672(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NFE4
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a KSR2 Gdf5
    Top Searches
    Ubiquitin-protein ligase Ubiquitin ELISA metalloproteinase Tumor necrosis Asprosin TRAP1A Alpha
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    Twitter