TFF1 ELISA Kit for Human(Homo sapiens) | EIAab.comTFF1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > TFF1(Gene name) > Human

TFF1 (Gene name),

Trefoil factor 1 (Protein name ), TFF1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TFF1(BCEI;PS2);

Protein name:

Trefoil factor 1;

Alternative:

PNR-2;Breast cancer estrogen-inducible protein;Protein pS2;Polypeptide P1.A(hP1.A);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer with GKN2; disulfide linked.

Function:

Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

Sequence:

50:

84:

CANKGCCFDD | TVRGVPWCFY | PNTIDVPPEE | ECEF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P04155

KEGG:

hsa:7031

MIM:

113710

Pfam:

PF00088

STRING:

9606.ENSP00000291527

String:

P04155

UniGene:

Hs.162807

Uniprot:

P04155

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ELISA Kit for Human Trefoil factor 1

Cat.:

E1049h

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Manual:

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Packing:

96T

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ELISA Kit for Human Trefoil factor 1

Cat.:

E1049d

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MSDS:

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Packing:

96T

ELISA Kit for Human Trefoil factor 1

Cat.:

E1049r

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MSDS:

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Packing:

96T

ELISA Kit for Human Trefoil factor 1

Cat.:

E1049m

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MSDS:

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Packing:

96T

CLIA Kit for Human Trefoil factor 1

Cat.:

U1049m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Trefoil factor 1

Cat.:

U1049h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Trefoil factor 1

Cat.:

U1049r

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MSDS:

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Packing:

96T

CLIA Kit for Human Trefoil factor 1

Cat.:

U1049d

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Packing:

96T

Polyclonal Antibody for Human Trefoil factor 1

Cat.:

P1049Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Trefoil factor 1

Cat.:

P1049Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Trefoil factor 1

Cat.:

P1049Rb-h

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40ug/0.2ml

Monoclonal Antibody for Human Trefoil factor 1

Protein for Human Trefoil factor 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7."
Jakowlew S.B. , Breathnach R. , Jeltsch J.-M. , Masiakowski P. , Chambon P.
Nucleic Acids Res.12:2861-2878(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Cloning of a gene expressed in human breast cancer and regulated by estrogen in MCF-7 cells."
Prud'Homme J.-F. , Fridlansky F. , le Cunff M. , Atger M. , Mercier-Bodart C. , Pichon M.-F. , Milgrom E.
DNA4:11-21(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue: Mammary cancer.
3.

"Structure of the human oestrogen-responsive gene pS2."
Jeltsch J.-M. , Roberts M. , Schatz C. , Garnier J.-M. , Brown A.M.C. , Chambon P.
Nucleic Acids Res.15:1401-1414(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Expression of the pS2 gene in human gastric cancer cells derived from poorly differentiated adenocarcinoma."
Takahashi H. , Kida N. , Fujii R. , Tanaka K. , Ohta M. , Mori K. , Hayashi K.
FEBS Lett.261:283-286(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Gastric carcinoma.
5.

"Complete primary structure of the human estrogen-responsive gene (pS2) product."
Mori K. , Fujii R. , Kida N. , Takahashi H. , Ohkubo S. , Fujino M. , Ohta M. , Hayashi K.
J. Biochem.107:73-76(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
6.

"Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region."
Berry A. , Scott H.S. , Kudoh J. , Talior I. , Korostishevsky M. , Wattenhofer M. , Guipponi M. , Barras C. , Rossier C. , Shibuya K. , Wang J. , Kawasaki K. , Asakawa S. , Minoshima S. , Shimizu N. , Antonarakis S.E. , Bonne-Tamir B.
Genomics68:22-29(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"The DNA sequence of human chromosome 21."
Hattori M. , Fujiyama A. , Taylor T.D. , Watanabe H. , Yada T. , Park H.-S. , Toyoda A. , Ishii K. , Totoki Y. , Choi D.-K. , Groner Y. , Soeda E. , Ohki M. , Takagi T. , Sakaki Y. , Taudien S. , Blechschmidt K. , Polley A. , more...
Nature405:311-319(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Colon.
tissue: Kidney.
tissue: Stomach.
9.

"Primary structure of human protein pS2."
Rio M.-C. , Lepage P. , Diemunsch P. , Roitsch C. , Chambon P.
C. R. Acad. Sci. III, Sci. Vie307:825-831(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-84
10.

"Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a Brichos domain-containing protein with homology to SP-C."
Westley B.R. , Griffin S.M. , May F.E.B.
Biochemistry44:7967-7975(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-84;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH GKN2
tissue: Stomach.
11.

"Identification of human urinary trefoil factor 1 as a novel calcium oxalate crystal growth inhibitor."
Chutipongtanate S. , Nakagawa Y. , Sritippayawan S. , Pittayamateekul J. , Parichatikanond P. , Westley B.R. , May F.E. , Malasit P. , Thongboonkerd V.
J. Clin. Invest.115:3613-3622(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-63;FUNCTION;TISSUE SPECIFICITY
12.

"Identification of a polypeptide secreted by human breast cancer cells (MCF-7) as the human estrogen-responsive gene (pS2) product."
Mori K. , Fujii R. , Kida N. , Ohta M. , Hayashi K.
Biochem. Biophys. Res. Commun.155:366-372(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-60
13.

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z. , Henzel W.J.
Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-39
14.

"Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa."
Rio M.C. , Bellocq J.-P. , Daniel J.Y. , Tomasetto C. , Lathe R. , Chenard M.P. , Batzenschlager A. , Chambon P.
Science241:705-708(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;SUBCELLULAR LOCATION
15.

"Expression of trefoil factors 1 and 2 in precancerous condition and gastric cancer."
Shi S.-Q. , Cai J.-T. , Yang J.-M.
World J. Gastroenterol.12:3119-3122(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
16.

"Molecular forms of trefoil factor 1 in normal gastric mucosa and its expression in normal and abnormal gastric tissues."
Ren J.L. , Luo J.-Y. , Lu Y.-P. , Wang L. , Shi H.-X.
World J. Gastroenterol.12:7361-7364(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
17.

"Tissue localization of human trefoil factors 1, 2, and 3."
Madsen J. , Nielsen O. , Tornoe I. , Thim L. , Holmskov U.
J. Histochem. Cytochem.55:505-513(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
18.

"NMR-based structural studies of the pNR-2/pS2 single domain trefoil peptide. Similarities to porcine spasmolytic peptide and evidence for a monomeric structure."
Polshakov V.I. , Frenkiel T.A. , Westley B.R. , Chadwick M.P. , May F.E.B. , Carr M.D. , Feeney J.
Eur. J. Biochem.233:847-855(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
19.

"High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein."
Polshakov V.I. , Williams M.A. , Gargaro A.R. , Frenkiel T.A. , Westley B.R. , Chadwick M.P. , May F.E.B. , Feeney J.
J. Mol. Biol.267:418-432(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
20.

"Somatic mutations of the trefoil factor family 1 gene in gastric cancer."
Park W.-S. , Oh R.-R. , Park J.-Y. , Lee J.-H. , Shin M.-S. , Kim H.-S. , Lee H.-K. , Kim Y.-S. , Kim S.-Y. , Lee S.-H. , Yoo N.-J. , Lee J.-Y.
Gastroenterology119:691-698(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ILE-32; LYS-32; ASP-34; LYS-37; ILE-46 AND VAL-55
21.

"Trefoil factor family-1 mutations enhance gastric cancer cell invasion through distinct signaling pathways."
Yio X. , Diamond M. , Zhang J.-Y. , Weinstein H. , Wang L.-H. , Werther L. , Itzkowitz S.
Gastroenterology130:1696-1706(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ASP-34 AND LYS-37;MUTAGENESIS OF CYS-82

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