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Index > Protein center > TFF3(Gene name) > Human
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  • TFF3 (Gene name),
  • Trefoil factor 3 (Protein name ),  TFF3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TFF3(ITF;TFI);
    Protein name:
    Trefoil factor 3;
    Alternative:
    Polypeptide P1.B(hP1.B);Intestinal trefoil factor(hITF);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer. Homodimer; disulfide-linked.
    Function:
    Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
    Subcellular Location:
    Secreted extracellular space extracellular matrix apical lamina
    Protein Attributes:
    Sequence length:
    80
    Sequence:
    50:
    MAARALCMLG | LVLALLSSSS | AEEYVGLSAN | QCAVPAKDRV | DCGYPHVTPK | 
    80:
    ECNNRGCCFD | SRIPGVPWCF | KPLQEAECTF | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    KEGG:
    Pfam:
    String:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Trefoil factor 3
    Cat.:
    E1656h
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    96T
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    ELISA Kit for Human Trefoil factor 3
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    E1656m
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    96T
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    ELISA Kit for Human Trefoil factor 3
    Cat.:
    E1656r
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    96T
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    ELISA Kit for Human Trefoil factor 3
    Cat.:
    E1656p
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    96T
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    ELISA Kit for Human Trefoil factor 3
    Cat.:
    E1656b
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    96T
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    ELISA Kit for Human Trefoil factor 3
    Cat.:
    E1656d
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    MSDS:
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    Packing:
    96T
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    CLIA Kit for Human Trefoil factor 3
    Cat.:
    U1656h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Trefoil factor 3
    Cat.:
    U1656d
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Trefoil factor 3
    Cat.:
    U1656r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Trefoil factor 3
    Cat.:
    U1656b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Trefoil factor 3
    Cat.:
    U1656p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Trefoil factor 3
    Cat.:
    U1656m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Trefoil factor 3
    Polyclonal Antibody for Human Trefoil factor 3
    Cat.:
    P1656Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Trefoil factor 3
    Cat.:
    P1656Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Trefoil factor 3
    Polyclonal Antibody for Human Trefoil factor 3
    Cat.:
    P1656Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Trefoil factor 3
    Monoclonal Antibody for Human Trefoil factor 3
    Monoclonal Antibody for Human Trefoil factor 3
    Monoclonal Antibody for Human Trefoil factor 3
    Monoclonal Antibody for Human Trefoil factor 3
    Monoclonal Antibody for Human Trefoil factor 3
    Monoclonal Antibody for Human Trefoil factor 3
    Protein for Human Trefoil factor 3
    Protein for Human Trefoil factor 3
    Protein for Human Trefoil factor 3
    Protein for Human Trefoil factor 3
    Protein for Human Trefoil factor 3
    Protein for Human Trefoil factor 3

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    Linearity
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    References
    1. 1.
      "hP1.B, a human P-domain peptide homologous with rat intestinal trefoil factor, is expressed also in the ulcer-associated cell lineage and the uterus."
      Hauser F. , Poulsom R. , Chinery R. , Rogers L.A. , Hanby A.M. , Wright N.A. , Hoffmann W.
      Proc. Natl. Acad. Sci. U.S.A.90:6961-6965(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      tissue: Small intestine.
    2. 2.
      "The three human trefoil genes TFF1, TFF2, and TFF3 are located within a region of 55 kb on chromosome 21q22.3."
      Seib T. , Blin N. , Hilgert K. , Seifert M. , Theisinger B. , Engel M. , Dooley S. , Zang K.D. , Welter C.
      Genomics40:200-202(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region."
      Berry A. , Scott H.S. , Kudoh J. , Talior I. , Korostishevsky M. , Wattenhofer M. , Guipponi M. , Barras C. , Rossier C. , Shibuya K. , Wang J. , Kawasaki K. , Asakawa S. , Minoshima S. , Shimizu N. , Antonarakis S.E. , Bonne-Tamir B.
      Genomics68:22-29(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    5. 6.
      "mRNA 5' region sequence incompleteness: a potential source of systematic errors in translation initiation codon assignment in human mRNAs."
      Casadei R. , Strippoli P. , D'Addabbo P. , Canaider S. , Lenzi L. , Vitale L. , Giannone S. , Frabetti F. , Facchin F. , Carinci P. , Zannotti M.
      Gene321:185-193(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-51
      tissue: Heart.
    6. 7.
      "Identification of human intestinal trefoil factor. Goblet cell-specific expression of a peptide targeted for apical secretion."
      Podolsky D.K. , Lynch-Devaney K. , Stow J.L. , Oates P. , Murgue B. , Debeaumont M. , Sands B.E. , Mahida Y.R.
      J. Biol. Chem.268:6694-6702(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-80;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Colon.
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    8. 9.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-36
    9. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-37;IDENTIFICATION BY MASS SPECTROMETRY
    10. 11.
      "Coexistence of intestinal trefoil factor (hITF) and oxytocin in magnocellular neurons in the human hypothalamus."
      Griepentrog T. , Bauer M. , Hornstein C. , Sauer H. , Jirikowski G.F.
      Horm. Metab. Res.32:121-124(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    11. 12.
      "Trefoil factor family-peptides promote migration of human bronchial epithelial cells: synergistic effect with epidermal growth factor."
      Oertel M. , Graness A. , Thim L. , Buhling F. , Kalbacher H. , Hoffmann W.
      Am. J. Respir. Cell Mol. Biol.25:418-424(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    12. 13.
      "Incorporation of mannose and glucose into prenylphosphate sugars in isolated human platelet membranes."
      De Luca S.
      Biochim. Biophys. Acta498:341-348(1977) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 22-80
    13. 14.
      "Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins."
      Muskett F.W. , May F.E. , Westley B.R. , Feeney J.
      Biochemistry42:15139-15147(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 22-80;SUBUNIT
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