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Index > Protein center > Tfrc(Gene name) > Rat
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  • Tfrc (Gene name),
  • Transferrin receptor protein 1 (Protein name ),  TFR1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tfrc(Trfr);
    Protein name:
    Transferrin receptor protein 1(TR;TfR;TfR1;Trfr);
    Alternative:

    CD:
    CD71;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Binds one transferrin molecule per subunit. Interacts with SH3BP4.
    Function:
    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein Melanosome
    Protein Attributes:
    Sequence length:
    622
    Sequence:
    50:
    IEFTDIIKQL | SQNTYTPREA | GSQKDENLAY | YIENLFHDFK | FSKVWRDEHY | 
    100:
    VKIQVKNSVS | QNLVTINSGS | NIDPVEAPEG | YVAFSKAGEV | TGKLVHANFG | 
    150:
    TKKDFEELNY | SVNGSLVIVR | AGKITFAEKV | ANAQSFNAIG | VLIYMDRNTF | 
    200:
    PVVEADLQFF | GHAHLGTGDP | YTPGFPSFNH | TQFPPSQSSG | LPSIPVQTIS | 
    250:
    RAPAEKLFKN | MEGNCPPSWN | IDSSCKLELS | QNQNVKLTVN | NVLKETRILN | 
    300:
    IFGVIKGYEE | PDRYIVVGAQ | RDAWGPGVAK | SSVGTGLLLK | LAQVFSDMIS | 
    350:
    KDGFRPSRSI | IFASWTAGDY | GAVGPTEWLE | GYLSSLHLKA | FTYINLDKVV | 
    400:
    LGTSNFKVSA | SPLLYTLMGK | IMQDVKHPID | GKYLYRNSNW | ISKIEELSLD | 
    450:
    NAAFPFLAYS | GIPAVSFCFC | EDEDYPYLGT | KLDTYEILIQ | KVPQLNQMVR | 
    500:
    TAAEVAGQFI | IKLTHDIELT | LDYEMYNSKL | LSFMKDLNQF | KADIKDMGLS | 
    550:
    LQWLYSARGD | YFRATSRLTT | DFHNAEKTNR | FVMREINDRI | MKVEYHFLSP | 
    600:
    YVSPRESPFR | HIFWGSGSHT | LSALVENLRL | RQKNITAFNE | TLFRNQLALA | 
    622:
    TWTIQGVANA | LSGDIWNIDN | EF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat TR
    Cat.:
    E0809h
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    96T
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    ELISA Kit for Rat TR
    Cat.:
    E0809p
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat TR
    Cat.:
    E0809m
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    MSDS:
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    96T
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    ELISA Kit for Rat TR
    Cat.:
    E0809r
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    96T
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    ELISA Kit for Rat TR
    Cat.:
    E0809c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat TR
    Cat.:
    E0809d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat TR
    Cat.:
    U0809c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat TR
    Cat.:
    U0809p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat TR
    Cat.:
    U0809h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat TR
    Cat.:
    U0809r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat TR
    Cat.:
    U0809d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat TR
    Cat.:
    U0809m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat TR
    Polyclonal Antibody for Rat TR
    Polyclonal Antibody for Rat TR
    Cat.:
    P0809Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat TR
    Cat.:
    P0809Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat TR
    Polyclonal Antibody for Rat TR
    Cat.:
    P0809Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat TR
    Monoclonal Antibody for Rat TR
    Monoclonal Antibody for Rat TR
    Monoclonal Antibody for Rat TR
    Monoclonal Antibody for Rat TR
    Monoclonal Antibody for Rat TR
    Protein for Rat TR
    Protein for Rat TR
    Protein for Rat TR
    Protein for Rat TR
    Protein for Rat TR
    Protein for Rat TR

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    References
    1. 1.
      "Characterization of rat transferrin receptor cDNA: the regulation of transferrin receptor mRNA in testes and in Sertoli cells in culture."
      Roberts K.P. , Griswold M.D.
      Mol. Endocrinol.4:531-542(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Testis.
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