Protein name:
Transferrin receptor protein 1 (TR;TfR;TfR1;Trfr) ;
Alternative:
CD:
CD71 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homodimer; disulfide-linked. Binds one transferrin molecule per subunit. Interacts with SH3BP4.
Function:
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.
Subcellular Location:
Cell membrane
Single-pass type II membrane protein
Melanosome
Protein Attributes:
50:
IEFTDIIKQL | SQNTYTPREA | GSQKDENLAY | YIENLFHDFK | FSKVWRDEHY |
100:
VKIQVKNSVS | QNLVTINSGS | NIDPVEAPEG | YVAFSKAGEV | TGKLVHANFG |
150:
TKKDFEELNY | SVNGSLVIVR | AGKITFAEKV | ANAQSFNAIG | VLIYMDRNTF |
200:
PVVEADLQFF | GHAHLGTGDP | YTPGFPSFNH | TQFPPSQSSG | LPSIPVQTIS |
250:
RAPAEKLFKN | MEGNCPPSWN | IDSSCKLELS | QNQNVKLTVN | NVLKETRILN |
300:
IFGVIKGYEE | PDRYIVVGAQ | RDAWGPGVAK | SSVGTGLLLK | LAQVFSDMIS |
350:
KDGFRPSRSI | IFASWTAGDY | GAVGPTEWLE | GYLSSLHLKA | FTYINLDKVV |
400:
LGTSNFKVSA | SPLLYTLMGK | IMQDVKHPID | GKYLYRNSNW | ISKIEELSLD |
450:
NAAFPFLAYS | GIPAVSFCFC | EDEDYPYLGT | KLDTYEILIQ | KVPQLNQMVR |
500:
TAAEVAGQFI | IKLTHDIELT | LDYEMYNSKL | LSFMKDLNQF | KADIKDMGLS |
550:
LQWLYSARGD | YFRATSRLTT | DFHNAEKTNR | FVMREINDRI | MKVEYHFLSP |
600:
YVSPRESPFR | HIFWGSGSHT | LSALVENLRL | RQKNITAFNE | TLFRNQLALA |
622:
TWTIQGVANA | LSGDIWNIDN | EF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Mouse
Rat
Chicken
Dog
Polyclonal Antibody for Rat TR
Polyclonal Antibody for Rat TR
Polyclonal Antibody for Rat TR
Polyclonal Antibody for Rat TR
Polyclonal Antibody for Rat TR
Polyclonal Antibody for Rat TR
Monoclonal Antibody for Rat TR
Monoclonal Antibody for Rat TR
Monoclonal Antibody for Rat TR
Monoclonal Antibody for Rat TR
Monoclonal Antibody for Rat TR
Monoclonal Antibody for Rat TR
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Testis .