Tgfb1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comTgfb1 ELISA Kit for Rat(Rattus norvegicus)

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Tgfb1 (Gene name),

Transforming growth factor beta-1 (Protein name ), TGFB1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (3)

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Gene name:

Tgfb1;

Protein name:

Transforming growth factor beta-1(TGF-beta-1);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

The inactive form consists of a TGFB1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The inactive complex can contain a latent TGFB1-binding protein. The active form is a homodimer of mature TGFB1; disulfide-linked. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT. Interacts with ASPN.

Function:

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

390

Sequence:

50:

100:

150:

200:

250:

300:

350:

390:

SASPCCVPQA | LEPLPIVYYV | GRKPKVEQLS | NMIVRSCKCS |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00019

SMR:

P17246

UniGene:

Rn.40136

KEGG:

rno:59086

String:

P17246

Uniprot:

P17246

FOR

ELISA Kit for Rat TGF-beta-1

Cat.:

E0124b

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96T

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ELISA Kit for Rat TGF-beta-1

Cat.:

E0124h

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96T

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ELISA Kit for Rat TGF-beta-1

Cat.:

E0124m

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96T

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ELISA Kit for Rat TGF-beta-1

Cat.:

E0124p

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96T

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ELISA Kit for Rat TGF-beta-1

Cat.:

E0124d

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Packing:

96T

ELISA Kit for Rat TGF-beta-1

Cat.:

E0124c

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96T

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ELISA Kit for Rat TGF-beta-1

Cat.:

E0124r

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96T

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CLIA Kit for Rat TGF-beta-1

Cat.:

U0124d

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MSDS:

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Packing:

96T

CLIA Kit for Rat TGF-beta-1

Cat.:

U0124c

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MSDS:

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Packing:

96T

CLIA Kit for Rat TGF-beta-1

Cat.:

U0124r

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Packing:

96T

CLIA Kit for Rat TGF-beta-1

Cat.:

U0124m

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Rat TGF-beta-1

Cat.:

U0124h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat TGF-beta-1

Cat.:

U0124p

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MSDS:

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Packing:

96T

CLIA Kit for Rat TGF-beta-1

Cat.:

U0124b

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Looking for manual.

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Packing:

96T

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Polyclonal Antibody for Rat TGF-beta-1

Cat.:

P0124Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat TGF-beta-1

Cat.:

P0124Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat TGF-beta-1

Cat.:

P0124Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat TGF-beta-1

Monoclonal Antibody for Rat TGF-beta-1

Protein for Rat TGF-beta-1

Cat.:

R0124h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Rat TGF-beta-1

Cat.:

R0124m

Price:

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Packing:

1mg

Purity:

>90%

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"Berberine attenuates podocytes injury caused by exosomes derived from high glucose-induced mesangial cells through TGFβ1-PI3K/AKT pathway"

Y Wang, LQ Tang, W Wei.

From:European Journal of Pharmacology

[2].

"Simvastatin Attenuates Intestinal Fibrosis Independent of the Anti-Inflammatory Effect by Promoting Fibroblast/Myofibroblast Apoptosis"

Y Abe, M Murano, N Murano, et al.

From:Digestive diseases and sciences

[3].

"Tanshinone IIA Attenuates Peritoneal Fibrosis through Inhibition of Fibrogenic Growth Factors Expression in Peritoneum in a Peritoneal Dialysis Rat"

Jiang Chunming, Zhang Miao, Sun Cheng, Tao Nana, Zhu Wei, Cao Dongwei and Feng Yuan

From:Informa healthcare

References

1.

"cDNA cloning by PCR of rat transforming growth factor beta-1."
Qian S.W. , Kondaiah P. , Roberts A.B. , Sporn M.B.
Nucleic Acids Res.18:3059-3059(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Heart.
2.

"Open reading frame sequence of rat TGF beta 1."
Dai W.-J. , Jiang H.-C. , Fu S.-B.
Submitted (2004-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Liver.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Kidney.
4.

"The first stage of transforming growth factor beta1 activation is release of the large latent complex from the extracellular matrix of growth plate chondrocytes by matrix vesicle stromelysin-1 (MMP-3)."
Maeda S. , Dean D.D. , Gomez R. , Schwartz Z. , Boyan B.D.
Calcif. Tissue Int.70:54-65(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
5.

"The effects of TGF-beta on bone."
Mundy G.R.
Ciba Found. Symp.157:137-143(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN BONE REMODELING;TISSUE SPECIFICITY

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