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Index > Protein center > Txn(Gene name) > Mouse
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  • Txn (Gene name),
  • Thioredoxin (Protein name ),  THIO_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Txn(Txn1);
    Protein name:
    Thioredoxin(Trx);
    Alternative:
    ATL-derived factor(ADF);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3. Interacts with APEX1; the interaction stimulates the FOS/JUN AP-1 DNA-binding activity in a redox-dependent manner.
    Function:
    ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
    Subcellular Location:
    Nucleus Cytoplasm Secreted Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus.
    Protein Attributes:
    Sequence length:
    105
    Sequence:
    50:
    MVKLIESKEA | FQEALAAAGD | KLVVVDFSAT | WCGPCKMIKP | FFHSLCDKYS | 
    100:
    NVVFLEVDVD | DCQDVAADCE | VKCMPTFQFY | KKGQKVGEFS | GANKEKLEAS | 
    105:
    ITEYA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Trx
    MSDS:
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    ELISA Kit for Mouse Trx
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    E0702h
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    ELISA Kit for Mouse Trx
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    E0702r
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    96T
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    ELISA Kit for Mouse Trx
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    E0702p
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    ELISA Kit for Mouse Trx
    Cat.:
    E0702m
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    ELISA Kit for Mouse Trx
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    E0702c
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    ELISA Kit for Mouse Trx
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    ELISA Kit for Mouse Trx
    Cat.:
    E0702b
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    Packing:
    96T
    CLIA Kit for Mouse Trx
    Cat.:
    U0702b
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    Packing:
    96T
    CLIA Kit for Mouse Trx
    Cat.:
    U0702c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Trx
    Cat.:
    U0702h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Trx
    Cat.:
    U0702r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Trx
    Cat.:
    U0702m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Trx
    Cat.:
    U0702p
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
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    CLIA Kit for Mouse Trx
    MSDS:
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    CLIA Kit for Mouse Trx
    MSDS:
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    Polyclonal Antibody for Mouse Trx
    Polyclonal Antibody for Mouse Trx
    Polyclonal Antibody for Mouse Trx
    Cat.:
    P0702Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Trx
    Cat.:
    P0702Rb-r
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    Polyclonal Antibody for Mouse Trx
    Cat.:
    P0702Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Trx
    Polyclonal Antibody for Mouse Trx
    Polyclonal Antibody for Mouse Trx
    Monoclonal Antibody for Mouse Trx
    Monoclonal Antibody for Mouse Trx
    Monoclonal Antibody for Mouse Trx
    Monoclonal Antibody for Mouse Trx
    Monoclonal Antibody for Mouse Trx
    Monoclonal Antibody for Mouse Trx
    Monoclonal Antibody for Mouse Trx
    Monoclonal Antibody for Mouse Trx
    Protein for Mouse Trx
    Protein for Mouse Trx
    Protein for Mouse Trx
    Protein for Mouse Trx
    Protein for Mouse Trx
    Protein for Mouse Trx
    Protein for Mouse Trx
    Protein for Mouse Trx

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    References
    1. 1.
      "ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction."
      Tagaya Y. , Maeda Y. , Mitsui A. , Kndo N. , Matsui H. , Hamuro J. , Brown N. , Arai K. , Yokota T. , Wakasugi H. , Yodoi J.
      EMBO J.8:757-764(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM;SEQUENCE REVISION
    3. 3.
      "Structure of the mouse thioredoxin-encoding gene and its processed pseudogene."
      Matsui M. , Taniguchi Y. , Hirota K. , Taketo M. , Yodoi J.
      Gene152:165-171(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/Sv.
      tissue: Liver.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Pancreas.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Colon.
      tissue: Thymus.
    6. 6.
      "Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function."
      Junn E. , Han S.H. , Im J.Y. , Yang Y. , Cho E.W. , Um H.D. , Kim D.K. , Lee K.W. , Han P.L. , Rhee S.G. , Choi I.
      J. Immunol.164:6287-6295(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TXNIP
    7. 7.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-39 AND LYS-94;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-8 AND LYS-94;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
      tissue: Liver.
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