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Index > Protein center > TKT(Gene name) > Human
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  • TKT (Gene name),
  • Transketolase (Protein name ),  TKT_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    TKT;
    Protein name:
    Transketolase(TK);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    N/A
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    623
    Sequence:
    50:
    MESYHKPDQQ | KLQALKDTAN | RLRISSIQAT | TAAGSGHPTS | CCSAAEIMAV | 
    100:
    LFFHTMRYKS | QDPRNPHNDR | FVLSKGHAAP | ILYAVWAEAG | FLAEAELLNL | 
    150:
    RKISSDLDGH | PVPKQAFTDV | ATGSLGQGLG | AACGMAYTGK | YFDKASYRVY | 
    200:
    CLLGDGELSE | GSVWEAMAFA | SIYKLDNLVA | ILDINRLGQS | DPAPLQHQMD | 
    250:
    IYQKRCEAFG | WHAIIVDGHS | VEELCKAFGQ | AKHQPTAIIA | KTFKGRGITG | 
    300:
    VEDKESWHGK | PLPKNMAEQI | IQEIYSQIQS | KKKILATPPQ | EDAPSVDIAN | 
    350:
    IRMPSLPSYK | VGDKIATRKA | YGQALAKLGH | ASDRIIALDG | DTKNSTFSEI | 
    400:
    FKKEHPDRFI | ECYIAEQNMV | SIAVGCATRN | RTVPFCSTFA | AFFTRAFDQI | 
    450:
    RMAAISESNI | NLCGSHCGVS | IGEDGPSQMA | LEDLAMFRSV | PTSTVFYPSD | 
    500:
    GVATEKAVEL | AANTKGICFI | RTSRPENAII | YNNNEDFQVG | QAKVVLKSKD | 
    550:
    DQVTVIGAGV | TLHEALAAAE | LLKKEKINIR | VLDPFTIKPL | DRKLILDSAR | 
    600:
    ATKGRILTVE | DHYYEGGIGE | AVSSAVVGEP | GITVTHLAVN | RVPRSGKPAE | 
    623:
    LLKMFGIDRD | AIAQAVRGLI | TKA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    SMR:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human TK
    Cat.:
    E0113h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human TK
    Cat.:
    E0113m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human TK
    Cat.:
    E0113r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human TK
    Cat.:
    E0113b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TK
    Cat.:
    U0113h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TK
    Cat.:
    U0113r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TK
    Cat.:
    U0113m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TK
    Cat.:
    U0113b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human TK
    Cat.:
    P0113Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TK
    Cat.:
    P0113Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TK
    Cat.:
    P0113Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TK
    Monoclonal Antibody for Human TK
    Monoclonal Antibody for Human TK
    Monoclonal Antibody for Human TK
    Monoclonal Antibody for Human TK
    Protein for Human TK
    Protein for Human TK
    Protein for Human TK
    Protein for Human TK

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals."
      McCool B.A. , Plonk S.G. , Martin P.R. , Singleton C.K.
      J. Biol. Chem.268:1397-1404(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Liver.
    2. 2.
      "Molecular cloning, sequence and chromosome localization of human transketolase."
      Jung E.-H. , Sheu K.-F.R.E. , Szabo P. , Blass J.P.
      Submitted (1993-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Brain.
    3. 3.
      "Molecular evolutionary analysis of the thiamine-diphosphate-dependent enzyme, transketolase."
      Schenk G. , Layfield R. , Candy J.M. , Duggleby R.G. , Nixon P.F.
      J. Mol. Evol.44:552-572(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Brain.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
    5. 5.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Kidney.
      tissue: Lymph.
    8. 8.
      "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
      Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
      Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-21
      tissue: Platelet.
    9. 9.
      "Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase."
      Abedinia M. , Layfield R. , Jones S.M. , Nixon P.F. , Mattick J.S.
      Biochem. Biophys. Res. Commun.183:1159-1166(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 224-623 (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
      tissue: Brain.
    10. 10.
      "Studies on the nature of thiamine pyrophosphate binding and dependency on divalent cations of transketolase from human erythrocytes."
      Jung E.H. , Takeuchi T. , Nishino K. , Itokawa Y.
      Int. J. Biochem.20:1255-1259(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COFACTOR
    11. 11.
      "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
      Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
      Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-295;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-275 AND THR-287;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    14. 14.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1; LYS-6; LYS-11; LYS-144; LYS-204; LYS-241; LYS-260 AND LYS-603;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-275; THR-287 AND SER-295;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "The crystal structure of human transketolase and new insights into its mode of action."
      Mitschke L. , Parthier C. , Schroder-Tittmann K. , Coy J. , Ludtke S. , Tittmann K.
      J. Biol. Chem.285:31559-31570(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 3-620 IN COMPLEXES WITH CALCIUM AND THIAMINE PYROPHOSPHATE
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