Gene name:
TLR7 (UNQ248/PRO285) ;
Protein name:
Toll-like receptor 7 ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with MYD88 via their respective TIR domains. Interacts with UNC93B1.
Function:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass type I membrane protein
Endosome
Lysosome
Cytoplasmic vesicle
phagosome
Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Protein Attributes:
50:
MVFPMWTLKR | QILILFNIIL | ISKLLGARWF | PKTLPCDVTL | DVPKNHVIVD |
100:
CTDKHLTEIP | GGIPTNTTNL | TLTINHIPDI | SPASFHRLDH | LVEIDFRCNC |
150:
VPIPLGSKNN | MCIKRLQIKP | RSFSGLTYLK | SLYLDGNQLL | EIPQGLPPSL |
200:
QLLSLEANNI | FSIRKENLTE | LANIEILYLG | QNCYYRNPCY | VSYSIEKDAF |
250:
LNLTKLKVLS | LKDNNVTAVP | TVLPSTLTEL | YLYNNMIAKI | QEDDFNNLNQ |
300:
LQILDLSGNC | PRCYNAPFPC | APCKNNSPLQ | IPVNAFDALT | ELKVLRLHSN |
350:
SLQHVPPRWF | KNINKLQELD | LSQNFLAKEI | GDAKFLHFLP | SLIQLDLSFN |
400:
FELQVYRASM | NLSQAFSSLK | SLKILRIRGY | VFKELKSFNL | SPLHNLQNLE |
450:
VLDLGTNFIK | IANLSMFKQF | KRLKVIDLSV | NKISPSGDSS | EVGFCSNART |
500:
SVESYEPQVL | EQLHYFRYDK | YARSCRFKNK | EASFMSVNES | CYKYGQTLDL |
550:
SKNSIFFVKS | SDFQHLSFLK | CLNLSGNLIS | QTLNGSEFQP | LAELRYLDFS |
600:
NNRLDLLHST | AFEELHKLEV | LDISSNSHYF | QSEGITHMLN | FTKNLKVLQK |
650:
LMMNDNDISS | STSRTMESES | LRTLEFRGNH | LDVLWREGDN | RYLQLFKNLL |
700:
KLEELDISKN | SLSFLPSGVF | DGMPPNLKNL | SLAKNGLKSF | SWKKLQCLKN |
750:
LETLDLSHNQ | LTTVPERLSN | CSRSLKNLIL | KNNQIRSLTK | YFLQDAFQLR |
800:
YLDLSSNKIQ | MIQKTSFPEN | VLNNLKMLLL | HHNRFLCTCD | AVWFVWWVNH |
850:
TEVTIPYLAT | DVTCVGPGAH | KGQSVISLDL | YTCELDLTNL | ILFSLSISVS |
900:
LFLMVMMTAS | HLYFWDVWYI | YHFCKAKIKG | YQRLISPDCC | YDAFIVYDTK |
950:
DPAVTEWVLA | ELVAKLEDPR | EKHFNLCLEE | RDWLPGQPVL | ENLSQSIQLS |
1000:
KKTVFVMTDK | YAKTENFKIA | FYLSHQRLMD | EKVDVIILIF | LEKPFQKSKF |
1049:
LQLRKRLCGS | SVLEWPTNPQ | AHPYFWQCLK | NALATDNHVA | YSQVFKETV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Toll-like receptor 7
ELISA Kit for Human Toll-like receptor 7
CLIA Kit for Human Toll-like receptor 7
CLIA Kit for Human Toll-like receptor 7
Polyclonal Antibody for Human Toll-like receptor 7
Polyclonal Antibody for Human Toll-like receptor 7
Monoclonal Antibody for Human Toll-like receptor 7
Monoclonal Antibody for Human Toll-like receptor 7
Protein for Human Toll-like receptor 7
Protein for Human Toll-like receptor 7
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Placenta .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Placenta .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT LEU-11
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Genome Res.13:2265-2270(2003)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION