TLR9 ELISA Kit for Human(Homo sapiens) | EIAab.comTLR9 ELISA Kit for Human(Homo sapiens)

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TLR9 (Gene name),

Toll-like receptor 9 (Protein name ), TLR9_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TLR9(UNQ5798/PRO19605);

Protein name:

Toll-like receptor 9;

Alternative:

CD:

CD289;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with CNPY3 (By similarity). Interacts (via transmembrane domain) with UNC93B1 (By similarity). Interacts with BTK.

Function:

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass type I membrane protein Endosome Lysosome Cytoplasmic vesicle phagosome Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.

Protein Attributes:

Sequence length:

1032

Sequence:

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1032:

GQRSFWAQLG | MALTRDNHHF | YNRNFCQGPT | AE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.87968

STRING:

9606.ENSP00000353874

MIM:

605474

SMR:

Q9NR96

KEGG:

hsa:54106

String:

Q9NR96

Pfam:

PF00560

Uniprot:

Q9NR96

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ELISA Kit for Human Toll-like receptor 9

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E0709h

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96T

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ELISA Kit for Human Toll-like receptor 9

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E0709p

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96T

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ELISA Kit for Human Toll-like receptor 9

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E0709d

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96T

ELISA Kit for Human Toll-like receptor 9

Cat.:

E0709m

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96T

ELISA Kit for Human Toll-like receptor 9

Cat.:

E0709b

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96T

CLIA Kit for Human Toll-like receptor 9

Cat.:

U0709p

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96T

CLIA Kit for Human Toll-like receptor 9

Cat.:

U0709h

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96T

CLIA Kit for Human Toll-like receptor 9

Cat.:

U0709b

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96T

CLIA Kit for Human Toll-like receptor 9

Cat.:

U0709d

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96T

CLIA Kit for Human Toll-like receptor 9

Cat.:

U0709m

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96T

Polyclonal Antibody for Human Toll-like receptor 9

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P0709Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Toll-like receptor 9

Cat.:

P0709Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Toll-like receptor 9

Monoclonal Antibody for Human Toll-like receptor 9

Protein for Human Toll-like receptor 9

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Three novel mammalian Toll-like receptors: gene structure, expression, and evolution."
Du X. , Poltorak A. , Wei Y. , Beutler B.
Eur. Cytokine Netw.11:362-371(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Monocytic leukemia.
2.

"Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9."
Chuang T.-H. , Ulevitch R.J.
Eur. Cytokine Netw.11:372-378(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 3; 4 AND 5)
tissue: Placenta.
3.

"A Toll-like receptor recognizes bacterial DNA."
Hemmi H. , Takeuchi O. , Kawai T. , Kaisho T. , Sato S. , Sanjo H. , Matsumoto M. , Hoshino K. , Wagner H. , Takeda K. , Akira S.
Nature408:740-745(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

Liu Z. , Wang J. , Xiao W.
Submitted (2007-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Natural selection in the TLR-related genes in the course of primate evolution."
Nakajima T. , Ohtani H. , Satta Y. , Uno Y. , Akari H. , Ishida T. , Kimura A.
Immunogenetics60:727-735(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
6.

"The heterogeneous allelic repertoire of human Toll-Like receptor (TLR) genes."
Georgel P. , Macquin C. , Bahram S.
PLoS ONE4:E7803-E7803(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
7.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Lymph.
10.

"Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells."
Takeshita F. , Leifer C.A. , Gursel I. , Ishii K.J. , Takeshita S. , Gursel M. , Klinman D.M.
J. Immunol.167:3555-3558(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase."
Doyle S.L. , Jefferies C.A. , Feighery C. , O'Neill L.A.
J. Biol. Chem.282:36953-36960(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH BTK
12.

"Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone."
Liu B. , Yang Y. , Qiu Z. , Staron M. , Hong F. , Li Y. , Wu S. , Li Y. , Hao B. , Bona R. , Han D. , Li Z.
Nat. Commun.1:79-79(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CNPY3 AND HSP90B1
13.

Liu B. , Yang Y. , Qiu Z. , Staron M. , Hong F. , Li Y. , Wu S. , Li Y. , Hao B. , Bona R. , Han D. , Li Z.
Nat. Commun.3:653-653(2012)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
14.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] HIS-901 AND MET-933

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