Gene name:
Tnfsf10 (Trail) ;
Protein name:
Tumor necrosis factor ligand superfamily member 10 ;
Alternative:
TNF-related apoptosis-inducing ligand (Protein TRAIL) ;
CD:
CD253 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MPSSGALKDL | SFSQHFRMMV | ICIVLLQVLL | QAVSVAVTYM | YFTNEMKQLQ |
100:
DNYSKIGLAC | FSKTDEDFWD | STDGEILNRP | CLQVKRQLYQ | LIEEVTLRTF |
150:
QDTISTVPEK | QLSTPPLPRG | GRPQKVAAHI | TGITRRSNSA | LIPISKDGKT |
200:
LGQKIESWES | SRKGHSFLNH | VLFRNGELVI | EQEGLYYIYS | QTYFRFQEAE |
250:
DASKMVSKDK | VRTKQLVQYI | YKYTSYPDPI | VLMKSARNSC | WSRDAEYGLY |
291:
SIYQGGLFEL | KKNDRIFVSV | TNEHLMDLDQ | EASFFGAFLI | N
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 10
ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 10
CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 10
CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 10
Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 10
Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 10
Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 10
Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 10
Protein for Mouse Tumor necrosis factor ligand superfamily member 10
Protein for Mouse Tumor necrosis factor ligand superfamily member 10
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
"Identification and characterization of a new member of the TNF family that induces apoptosis."
Wiley S.R.
,
Schooley K.
,
Smolak P.J.
,
Din W.S.
,
Huang C.-P.
,
Nicholl J.K.
,
Sutherland G.R.
,
Davis-Smith T.
,
Rauch C.
,
Smith C.A.
,
Goodwin R.G.
Immunity3:673-682(1995)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]