Gene name:
Lta (Tnfb;Tnfsf1) ;
Protein name:
Lymphotoxin-alpha (LT-alpha) ;
Alternative:
Tumor necrosis factor ligand superfamily member 1 ;TNF-beta ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits.
Function:
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
Subcellular Location:
Secreted
Membrane
The homotrimer is secreted (By similarity). The heterotrimer is membrane-associated.
Protein Attributes:
50:
MTPLGRLHLL | RVLSTPPVFL | LGLLLALPLG | AQGLSGVRFS | ASRTAHQPPQ |
100:
KHLTHGLLKP | AAHLVGYPSK | QNSLLWRANT | DRAFLRHGFS | LNNNSLLIPT |
150:
SGLYFVYSQV | VFSGESCSPR | AIPTPIYLAH | EVQLFSSQYP | FHVPLLSAQK |
200:
SVYPGLQGPW | VRSMYQGAVF | LLSKGDQLST | HTDGISHLHF | SPSTVFFGAF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Pig
Bovine
Rat
Dog
Rabbit
ELISA Kit for Rat LT-alpha
ELISA Kit for Rat LT-alpha
ELISA Kit for Rat LT-alpha
ELISA Kit for Rat LT-alpha
ELISA Kit for Rat LT-alpha
ELISA Kit for Rat LT-alpha
ELISA Kit for Rat LT-alpha
CLIA Kit for Rat LT-alpha
CLIA Kit for Rat LT-alpha
CLIA Kit for Rat LT-alpha
CLIA Kit for Rat LT-alpha
CLIA Kit for Rat LT-alpha
CLIA Kit for Rat LT-alpha
CLIA Kit for Rat LT-alpha
Polyclonal Antibody for Rat LT-alpha
Polyclonal Antibody for Rat LT-alpha
Polyclonal Antibody for Rat LT-alpha
Polyclonal Antibody for Rat LT-alpha
Polyclonal Antibody for Rat LT-alpha
Polyclonal Antibody for Rat LT-alpha
Polyclonal Antibody for Rat LT-alpha
Monoclonal Antibody for Rat LT-alpha
Monoclonal Antibody for Rat LT-alpha
Monoclonal Antibody for Rat LT-alpha
Monoclonal Antibody for Rat LT-alpha
Monoclonal Antibody for Rat LT-alpha
Monoclonal Antibody for Rat LT-alpha
Monoclonal Antibody for Rat LT-alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
Sprague-Dawley .
tissue :
Testis .
2.
"The genomic sequence and comparative analysis of the rat major histocompatibility complex."
Hurt P.
,
Walter L.
,
Sudbrak R.
,
Klages S.
,
Mueller I.
,
Shiina T.
,
Inoko H.
,
Lehrach H.
,
Guenther E.
,
Reinhardt R.
,
Himmelbauer H.
Genome Res.14:631-639(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .