Faslg ELISA Kit for Mouse(Mus musculus) | EIAab.comFaslg ELISA Kit for Mouse(Mus musculus)

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Faslg (Gene name),

Tumor necrosis factor ligand superfamily member 6 (Protein name ), TNFL6_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Faslg(Apt1lg1;Cd95l;Fasl;gld;Tnfsf6);

Protein name:

Tumor necrosis factor ligand superfamily member 6;

Alternative:

Fas antigen ligand(Fas ligand);CD95 ligand(CD95-L);

CD:

CD178;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotrimer (Probable). Interacts with ARHGAP9, BAIAP2L1, BTK, CACNB3, CACNB4, CRK, DLG2, DNMBP, DOCK4, EPS8L3, FGR, FYB, FYN, HCK, ITK, ITSN2, KALRN, LYN, MACC1, MIA, MPP4, MYO15A, NCF1, NCK1, NCK2, NCKIPSD, OSTF1, PIK3R1, PSTPIP1, RIMBP3C, SAMSN1, SH3GL3, SH3PXD2B, SH3PXD2A, SH3RF2, SKAP2, SNX33, SNX9, SORBS3, SPTA1, SRC, SRGAP1, SRGAP2, SRGAP3, TEC, TJP3 and YES1.

Function:

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Subcellular Location:

Tumor necrosis factor ligand superfamily member 6, soluble form Secreted May be released into the extracellular fluid, probably by cleavage form the cell surface.

Protein Attributes:

Sequence length:

279

Sequence:

50:

100:

150:

200:

250:

279:

SADHLYVNIS | QLSLINFEES | KTFFGLYKL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00229

SMR:

P41047

String:

P41047

UniGene:

Mm.3355

KEGG:

mmu:14103

Uniprot:

P41047

FOR

ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

E0031m

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96T

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ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

E0031r

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96T

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ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

E0031h

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ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

E0031p

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Packing:

96T

CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

U0031p

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

U0031h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

U0031m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

U0031r

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

P0031Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

P0031Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 6

Cat.:

P0031Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 6

Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 6

Protein for Mouse Tumor necrosis factor ligand superfamily member 6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand."
Takahashi T. , Tanaka M. , Brannan C.I. , Jenkins N.A. , Copeland N.G. , Suda T. , Nagata S.
Cell76:969-976(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM FASL)
2.

"Comparative molecular modelling of the Fas-ligand and other members of the TNF family."
Peitsch M.C. , Tschopp J.
Mol. Immunol.32:761-772(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM FASL);3D-STRUCTURE MODELING
strain: C57BL/6.
3.

"The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster."
Lynch D.H. , Watson M.L. , Alderson M.R. , Baum P.R. , Miller R.E. , Tough T. , Gibson M. , Davis-Smith T. , Smith C.A. , Hunter K.
Immunity1:131-136(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM FASL)
4.

"Mus musculus Balb/c Fas ligand differs from 129/SV Fas ligand in two amino acids."
Fenner M.H. , Shioda T. , Isselbacher K.J.
Submitted (1996-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM FASL)
strain: BALB/c.
5.

"Cloning and expression of a short Fas ligand: a new alternatively spliced product of the mouse Fas ligand gene."
Ayroldi E. , D'Adamio F. , Zollo O. , Agostini M. , Moraca R. , Cannarile L. , Migliorati G. , Delfino D.V. , Riccardi C.
Blood94:3456-3467(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM FASLS)
strain: C3H.
tissue: Spleen.
6.

"Characterization of the non-functional Fas ligand of gld mice."
Hahne M. , Peitsch M.C. , Irmler M. , Schroeter M. , Lowin B. , Rousseau M. , Bron C. , Renno T. , French L. , Tschopp J.
Int. Immunol.7:1381-1386(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT GLD
7.

"Polymorphism of murine Fas ligand that affects the biological activity."
Kayagaki N. , Yamaguchi N. , Nagao F. , Matsuo S. , Maeda H. , Okumura K. , Yagita H.
Proc. Natl. Acad. Sci. U.S.A.94:3914-3919(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ALA-184 AND GLY-218
strain: BALB/c.
strain: C3H.
strain: C57BL/6.
strain: DBA/1.
strain: DBA/2.
strain: MRL.
strain: NOD.
strain: NZB.
strain: NZW.
strain: SJL.

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