TNNI3 ELISA Kit for Human(Homo sapiens) | EIAab.comTNNI3 ELISA Kit for Human(Homo sapiens)

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TNNI3 (Gene name),

Troponin I, cardiac muscle (Protein name ), TNNI3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

TNNI3(TNNC1);

Protein name:

Troponin I, cardiac muscle;

Alternative:

Cardiac troponin I;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1.

Function:

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

210

Sequence:

50:

100:

150:

200:

210:

MEGRKKKFES |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P19429

MIM:

115210

Pfam:

PF00992

UniGene:

Hs.709179

STRING:

9606.ENSP00000341838

KEGG:

hsa:7137

SMR:

P19429

Uniprot:

P19429

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ELISA Kit for Human Troponin I, cardiac muscle

Cat.:

E0478m

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96T

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ELISA Kit for Human Troponin I, cardiac muscle

Cat.:

E0478r

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96T

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ELISA Kit for Human Troponin I, cardiac muscle

Cat.:

E0478d

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96T

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ELISA Kit for Human Troponin I, cardiac muscle

Cat.:

E0478c

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96T

ELISA Kit for Human Troponin I, cardiac muscle

Cat.:

E0478h

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96T

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ELISA Kit for Human Troponin I, cardiac muscle

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ELISA Kit for Human Troponin I, cardiac muscle

Cat.:

E0478b

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96T

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CLIA Kit for Human Troponin I, cardiac muscle

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CLIA Kit for Human Troponin I, cardiac muscle

Cat.:

U0478r

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Looking for manual.

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96T

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CLIA Kit for Human Troponin I, cardiac muscle

Cat.:

U0478m

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human Troponin I, cardiac muscle

Cat.:

U0478b

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Packing:

96T

CLIA Kit for Human Troponin I, cardiac muscle

Cat.:

U0478c

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Packing:

96T

CLIA Kit for Human Troponin I, cardiac muscle

Cat.:

U0478d

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Packing:

96T

CLIA Kit for Human Troponin I, cardiac muscle

Cat.:

U0478h

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96T

Polyclonal Antibody for Human Troponin I, cardiac muscle

Cat.:

P0478Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Troponin I, cardiac muscle

Cat.:

P0478Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Troponin I, cardiac muscle

Cat.:

P0478Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Troponin I, cardiac muscle

Monoclonal Antibody for Human Troponin I, cardiac muscle

Protein for Human Troponin I, cardiac muscle

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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Citations

[1].

"Protective Role of Statins in Patients With Acute Coronary Syndrome Aged≥ 75 Years With Low LDL-C Who Underwent Percutaneous Coronary Intervention"

C Bu, Y Zhao, H Ma,

From:Angiology

References

1.

"Molecular cloning of human cardiac troponin I using polymerase chain reaction."
Vallins W.J. , Brand N.J. , Dabhade N. , Butler-Browne G. , Yacoub M.H. , Barton P.J.R.
FEBS Lett.270:57-61(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Heart muscle.
2.

"Cloning and expression in Escherichia coli of the cDNA encoding human cardiac troponin I."
Armour K.L. , Harris W.J. , Tempest P.R.
Gene131:287-292(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 85;NUCLEOTIDE SEQUENCE [MRNA]
3.

"Troponin I isoform expression in human heart."
Hunkeler N.M. , Kullman J. , Murphy A.M.
Circ. Res.69:1409-1414(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Isolation and characterization of the human cardiac troponin I gene (TNNI3)."
Bhavsar P.K. , Brand N.J. , Yacoub M.H. , Barton P.J.R.
Genomics35:11-23(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"A common motif of two adjacent phosphoserines in bovine, rabbit and human cardiac troponin I."
Mittmann K. , Jaquet K. , Heilmeyer L.M.G. Jr.
FEBS Lett.273:41-45(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 11-36;ACETYLATION AT ALA-2;PHOSPHORYLATION AT SER-23 AND SER-24
6.

"The ordered phosphorylation of cardiac troponin I by the cAMP-dependent protein kinase -- structural consequences and functional implications."
Keane N.E. , Quirk P.G. , Gao Y. , Patchell V.B. , Perry S.V. , Levine B.A.
Eur. J. Biochem.248:329-337(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-23 AND SER-24
7.

"p21-activated kinase increases the calcium sensitivity of rat triton-skinned cardiac muscle fiber bundles via a mechanism potentially involving novel phosphorylation of troponin I."
Buscemi N. , Foster D.B. , Neverova I. , Van Eyk J.E.
Circ. Res.91:509-516(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-150 BY PAK3
8.

"Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function."
Haworth R.S. , Cuello F. , Herron T.J. , Franzen G. , Kentish J.C. , Gautel M. , Avkiran M.
Circ. Res.95:1091-1099(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-23 AND SER-24
9.

"Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I."
Kedar V. , McDonough H. , Arya R. , Li H.-H. , Rockman H.A. , Patterson C.
Proc. Natl. Acad. Sci. U.S.A.101:18135-18140(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRIM63
10.

"Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1."
You B. , Yan G. , Zhang Z. , Yan L. , Li J. , Ge Q. , Jin J.P. , Sun J.
Biochem. J.418:93-101(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STK4/MST1;PHOSPHORYLATION AT THR-31; THR-51; THR-129 AND THR-143
11.

"Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart."
Zhang P. , Kirk J.A. , Ji W. , dos Remedios C.G. , Kass D.A. , Van Eyk J.E. , Murphy A.M.
Circulation126:1828-1837(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-5; SER-6; SER-23; SER-24; TYR-26; SER-42; SER-44; THR-51; SER-77; THR-78; THR-143; SER-166; THR-181 AND SER-199
12.

"Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C."
Li M.X. , Spyracopoulos L. , Sykes B.D.
Biochemistry38:8289-8298(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 148-164
13.

"Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil."
Wang X. , Li M.X. , Sykes B.D.
J. Biol. Chem.277:31124-31133(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 149-165 IN COMPLEX WITH CARDIAC TROPONIN C
14.

"Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy."
Kimura A. , Harada H. , Park J.-E. , Nishi H. , Satoh M. , Takahashi M. , Hiroi S. , Sasaoka T. , Ohbuchi N. , Nakamura T. , Koyanagi T. , Hwang T.-H. , Choo J. , Chung K.-S. , Hasegawa A. , Nagai R. , Okazaki O. , Nakamura H. , more...
Nat. Genet.16:379-382(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMH7 GLY-145 AND GLN-206
15.

"Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly."
Niimura H. , Patton K.K. , McKenna W.J. , Soults J. , Maron B.J. , Seidman J.G. , Seidman C.E.
Circulation105:446-451(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMH7 SER-82 AND ASN-196
16.

"Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations."
Mogensen J. , Kubo T. , Duque M. , Uribe W. , Shaw A. , Murphy R. , Gimeno J.R. , Elliott P. , McKenna W.J.
J. Clin. Invest.111:209-216(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS RCM1 GLN-144; TRP-145; THR-171; GLU-178; HIS-190 AND HIS-192
17.

"Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy."
Richard P. , Charron P. , Carrier L. , Ledeuil C. , Cheav T. , Pichereau C. , Benaiche A. , Isnard R. , Dubourg O. , Burban M. , Gueffet J.-P. , Millaire A. , Desnos M. , Schwartz K. , Hainque B. , Komajda M.
Circulation107:2227-2232(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMH7 GLN-141; VAL-157; PRO-162; LYS-177 DEL; GLN-186 AND ASN-196
18.

Richard P. , Charron P. , Carrier L. , Ledeuil C. , Cheav T. , Pichereau C. , Benaiche A. , Isnard R. , Dubourg O. , Burban M. , Gueffet J.-P. , Millaire A. , Desnos M. , Schwartz K. , Hainque B. , Komajda M.
Circulation109:3258-3258(2004)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
19.

"Mutation spectrum in a large cohort of unrelated consecutive patients with hypertrophic cardiomyopathy."
Erdmann J. , Daehmlow S. , Wischke S. , Senyuva M. , Werner U. , Raible J. , Tanis N. , Dyachenko S. , Hummel M. , Hetzer R. , Regitz-Zagrosek V.
Clin. Genet.64:339-349(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMH7 PHE-166
20.

"Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy."
Murphy R.T. , Mogensen J. , Shaw A. , Kubo T. , Hughes S. , McKenna W.J.
Lancet363:371-372(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMD2A VAL-2
21.

"Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling."
Ingles J. , Doolan A. , Chiu C. , Seidman J. , Seidman C. , Semsarian C.
J. Med. Genet.42:E59-E59(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMH7 PRO-162; GLN-162 AND HIS-204
22.

"Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy."
Carballo S. , Robinson P. , Otway R. , Fatkin D. , Jongbloed J.D. , de Jonge N. , Blair E. , van Tintelen J.P. , Redwood C. , Watkins H.
Circ. Res.105:375-382(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMD1FF GLN-36 AND LYS-185
23.

"Clinical and mutational spectrum in a cohort of 105 unrelated patients with dilated cardiomyopathy."
Millat G. , Bouvagnet P. , Chevalier P. , Sebbag L. , Dulac A. , Dauphin C. , Jouk P.S. , Delrue M.A. , Thambo J.B. , Le Metayer P. , Seronde M.F. , Faivre L. , Eicher J.C. , Rousson R.
Eur. J. Med. Genet.54:E570-E575(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMD1FF GLY-116

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