Gene name:
FAS (APT1;TNFRSF6) ;
Protein name:
Tumor necrosis factor receptor superfamily member 6 ;
Alternative:
Apoptosis-mediating surface antigen FAS ;Apo-1 antigen ;FASLG receptor ;
CD:
CD95 ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Binds DAXX and RIPK1. Interacts with HIPK3. Part of a complex containing HIPK3 and FADD. Interacts with BRE and FEM1B (By similarity). Interacts with FADD.
Function:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MSGIWVLLSL | VFTCIAGPLS | KGDDAQVTDP | DSEMVKLNIT | KRESECPEGQ |
100:
HREGQFCCQP | CPPGKRKHAD | CTSPGGAPQC | VPCSEGEDYT | DKNHHSSKCR |
150:
RCRVCDGEHG | LEVEKNCTRT | QNTKCRCKPN | FFCHTSQCEH | CNPCTTCEHG |
200:
VIENCTPTSN | TKCREVFQSA | GSRSNLHWLW | ALLILIPVPA | LVYREVKRRC |
250:
RRKENGYQKP | ITSNAEEVPM | IKDVDLGKYI | TRIAEQMKIT | EVKDFVRKNG |
300:
IEETKIDEIM | HDNPKDTAEQ | KVQLLRNWYL | YHGKKDAYCT | LIQGLRKAKL |
332:
SALADKINDI | VQKDVTSEQE | NANSQNENES | LT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Pig
Bovine
ELISA Kit for Pig Tumor necrosis factor receptor superfamily member 6
ELISA Kit for Pig Tumor necrosis factor receptor superfamily member 6
ELISA Kit for Pig Tumor necrosis factor receptor superfamily member 6
ELISA Kit for Pig Tumor necrosis factor receptor superfamily member 6
ELISA Kit for Pig Tumor necrosis factor receptor superfamily member 6
CLIA Kit for Pig Tumor necrosis factor receptor superfamily member 6
CLIA Kit for Pig Tumor necrosis factor receptor superfamily member 6
CLIA Kit for Pig Tumor necrosis factor receptor superfamily member 6
CLIA Kit for Pig Tumor necrosis factor receptor superfamily member 6
CLIA Kit for Pig Tumor necrosis factor receptor superfamily member 6
Polyclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Polyclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Polyclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Polyclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Polyclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Monoclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Monoclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Monoclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Monoclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Monoclonal Antibody for Pig Tumor necrosis factor receptor superfamily member 6
Protein for Pig Tumor necrosis factor receptor superfamily member 6
Protein for Pig Tumor necrosis factor receptor superfamily member 6
Protein for Pig Tumor necrosis factor receptor superfamily member 6
Protein for Pig Tumor necrosis factor receptor superfamily member 6
Protein for Pig Tumor necrosis factor receptor superfamily member 6
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]