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Index > Protein center > TPMT(Gene name) > Human
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  • TPMT (Gene name),
  • Thiopurine S-methyltransferase (Protein name ),  TPMT_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    TPMT;
    Protein name:
    Thiopurine S-methyltransferase;
    Alternative:
    Thiopurine methyltransferase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    245
    Sequence:
    50:
    MDGTRTSLDI | EEYSDTEVQK | NQVLTLEEWQ | DKWVNGKTAF | HQEQGHQLLK | 
    100:
    KHLDTFLKGK | SGLRVFFPLC | GKAVEMKWFA | DRGHSVVGVE | ISELGIQEFF | 
    150:
    TEQNLSYSEE | PITEIPGTKV | FKSSSGNISL | YCCSIFDLPR | TNIGKFDMIW | 
    200:
    DRGALVAINP | GDRKCYADTM | FSLLGKKFQY | LLCVLSYDPT | KHPGPPFYVP | 
    245:
    HAEIERLFGK | ICNIRCLEKV | DAFEERHKSW | GIDCLFEKLY | LLTEK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Thiopurine S-methyltransferase
    Cat.:
    E10435h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Thiopurine S-methyltransferase
    MSDS:
    Please sign in first.
    ELISA Kit for Human Thiopurine S-methyltransferase
    MSDS:
    Please sign in first.
    ELISA Kit for Human Thiopurine S-methyltransferase
    Cat.:
    E10435m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Thiopurine S-methyltransferase
    Cat.:
    E10435r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Thiopurine S-methyltransferase
    MSDS:
    Please sign in first.
    CLIA Kit for Human Thiopurine S-methyltransferase
    Cat.:
    U10435m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Thiopurine S-methyltransferase
    MSDS:
    Please sign in first.
    CLIA Kit for Human Thiopurine S-methyltransferase
    MSDS:
    Please sign in first.
    CLIA Kit for Human Thiopurine S-methyltransferase
    MSDS:
    Please sign in first.
    CLIA Kit for Human Thiopurine S-methyltransferase
    Cat.:
    U10435h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Thiopurine S-methyltransferase
    Cat.:
    U10435r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Thiopurine S-methyltransferase
    Polyclonal Antibody for Human Thiopurine S-methyltransferase
    Polyclonal Antibody for Human Thiopurine S-methyltransferase
    Cat.:
    P10435Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Thiopurine S-methyltransferase
    Polyclonal Antibody for Human Thiopurine S-methyltransferase
    Polyclonal Antibody for Human Thiopurine S-methyltransferase
    Monoclonal Antibody for Human Thiopurine S-methyltransferase
    Monoclonal Antibody for Human Thiopurine S-methyltransferase
    Monoclonal Antibody for Human Thiopurine S-methyltransferase
    Monoclonal Antibody for Human Thiopurine S-methyltransferase
    Monoclonal Antibody for Human Thiopurine S-methyltransferase
    Monoclonal Antibody for Human Thiopurine S-methyltransferase
    Protein for Human Thiopurine S-methyltransferase
    Protein for Human Thiopurine S-methyltransferase
    Protein for Human Thiopurine S-methyltransferase
    Protein for Human Thiopurine S-methyltransferase
    Protein for Human Thiopurine S-methyltransferase
    Protein for Human Thiopurine S-methyltransferase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA."
      Honchel R. , Aksoy I.A. , Szumlanski C. , Wood T.C. , Otterness D.M. , Wieben E.D. , Weinshilboum R.M.
      Mol. Pharmacol.43:878-887(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      tissue: Kidney.
    2. 2.
      "Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1."
      Lee D. , Szumlanski C.L. , Houtman J. , Honchel R. , Rojas K. , Overhauser J. , Weiben E.D. , Weinshilboum R.M.
      Drug Metab. Dispos.23:398-405(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism."
      Szumlanski C. , Otterness D. , Her C. , Lee D. , Brandriff B. , Kelsell D. , Spurr N. , Lennard L. , Wieben E. , Weinshilboum R.M.
      DNA Cell Biol.15:17-30(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS TPMT DEFICIENCY THR-154 AND CYS-240
    4. 4.
      "Promoter and intronic sequences of the human thiopurine S-methyltransferase (TPMT) gene isolated from a human PAC1 genomic library."
      Krynetski E.Y. , Fessing M.Y. , Yates C.R. , Sun D. , Schuetz J.D. , Evans W.E.
      Pharm. Res.14:1672-1678(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-49 AND PHE-180;VARIANTS TPMT DEFICIENCY THR-154 AND CYS-240
    6. 6.
      "Genomic structure of thiopurine S-methyltransferase gene."
      Nakamura Y.
      Submitted (2000-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Bone marrow.
    9. 9.
      "Detection of known and new mutations in the thiopurine S-methyltransferase gene by single-strand conformation polymorphism analysis."
      Spire-Vayron de la Moureyre C. , Debuysere H. , Sabbagh N. , Marez D. , Vinner E. , Chevalier E.D. , Lo-Guidice J.-M. , Broly F.
      Hum. Mutat.12:177-185(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 210-245;VARIANT TPMT DEFICIENCY GLN-227
    10. 10.
      "Structural basis of substrate recognition in thiopurine s-methyltransferase."
      Peng Y. , Feng Q. , Wilk D. , Adjei A.A. , Salavaggione O.E. , Weinshilboum R.M. , Yee V.C.
      Biochemistry47:6216-6225(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES;MUTAGENESIS OF ARG-152
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    13. 13.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    14. 14.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-58;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      "Structural basis of allele variation of human thiopurine-S-methyltransferase."
      Wu H. , Horton J.R. , Battaile K. , Allali-Hassani A. , Martin F. , Zeng H. , Loppnau P. , Vedadi M. , Bochkarev A. , Plotnikov A.N. , Cheng X.
      Proteins67:198-208(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.58 ANGSTROMS) OF 16-245 IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE;SUBUNIT;CHARACTERIZATION OF VARIANTS TPMT DEFICIENCY THR-154 AND CYS-240
    17. 17.
      "A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase."
      Krynetski E.Y. , Schuetz J.D. , Galpin A.J. , Pui C.-H. , Relling M.V. , Evans W.E.
      Proc. Natl. Acad. Sci. U.S.A.92:949-953(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TPMT DEFICIENCY PRO-80
    18. 18.
      "Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians."
      Tai H.-L. , Krynetski E.Y. , Yates C.R. , Loennechen T. , Fessing M.Y. , Krynetskaia N.F. , Evans W.E.
      Am. J. Hum. Genet.58:694-702(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY THR-154 AND CYS-240
    19. 19.
      "Azathioprine-induced severe pancytopenia due to a homozygous two-point mutation of the thiopurine methyltransferase gene in a patient with juvenile HLA-B27-associated spondylarthritis."
      Leipold G. , Schuetz E. , Haas J.P. , Oellerich M.
      Arthritis Rheum.40:1896-1898(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY THR-154 AND CYS-240
    20. 20.
      "Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity."
      Tai H.-L. , Krynetski E.Y. , Schuetz E.G. , Yanishevski Y. , Evans W.E.
      Proc. Natl. Acad. Sci. U.S.A.94:6444-6449(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS TPMT DEFICIENCY PRO-80 AND THR-154;MECHANISM FOR THE GENETIC POLYMORPHISM OF TPMT ACTIVITY
    21. 21.
      "Thiopurine methyltransferase alleles in British and Ghanaian populations."
      Ameyaw M.-M. , Collie-Duguid E.S.R. , Powrie R.H. , Ofori-Adjei D. , McLeod H.L.
      Hum. Mol. Genet.8:367-370(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY PRO-80; THR-154 AND CYS-240
    22. 22.
      "Polymorphism of the thiopurine S-methyltransferase gene in African-Americans."
      Hon Y.Y. , Fessing M.Y. , Pui C.-H. , Relling M.V. , Krynetski E.Y. , Evans W.E.
      Hum. Mol. Genet.8:371-376(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TPMT DEFICIENCY HIS-215
    23. 23.
      "The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations."
      Collie-Duguid E.S.R. , Pritchard S.C. , Powrie R.H. , Sludden J. , Collier D.A. , Li T. , McLeod H.L.
      Pharmacogenetics9:37-42(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY PRO-80; THR-154 AND CYS-240;FREQUENCY AND DISTRIBUTION OF ALLELES
    24. 24.
      "Genetic analysis of thiopurine methyltransferase polymorphism in a Japanese population."
      Hiratsuka M. , Inoue T. , Omori F. , Agatsuma Y. , Mizugaki M.
      Mutat. Res.448:91-95(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY PRO-80; THR-154 AND CYS-240;FREQUENCY AND DISTRIBUTION OF ALLELES
    25. 25.
      "Thiopurine S-methyltransferase pharmacogenetics: variant allele functional and comparative genomics."
      Salavaggione O.E. , Wang L. , Wiepert M. , Yee V.C. , Weinshilboum R.M.
      Pharmacogenet. Genomics15:801-815(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY PRO-80; THR-154; HIS-215; GLN-227 AND CYS-240;VARIANTS SER-49 AND PHE-180;CHARACTERIZATION OF VARIANTS TPMT DEFICIENCY PRO-80; THR-154; HIS-215; GLN-227 AND CYS-240;CHARACTERIZATION OF VARIANTS SER-49 AND PHE-180
    26. 26.
      "Severe azathioprine-induced myelotoxicity in a kidney transplant patient with thiopurine S-methyltransferase-deficient genotype (TPMT*3A/*3C)."
      Kurzawski M. , Dziewanowski K. , Ciechanowski K. , Drozdzik M.
      Transpl. Int.18:623-625(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY THR-154 AND CYS-240
    27. 27.
      "Molecular analysis of thiopurine S-methyltransferase alleles in Taiwan aborigines and Taiwanese."
      Lu H.-F. , Shih M.-C. , Chang Y.-S. , Chang J.-Y. , Ko Y.-C. , Chang S.-J. , Chang J.-G.
      J. Clin. Pharm. Ther.31:93-98(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY PRO-80; THR-154 AND CYS-240;FREQUENCY AND DISTRIBUTION OF ALLELES
    28. 28.
      "Frequency of the thiopurine S-methyltransferase alleles in the ancient genetic population isolate of Sardinia."
      Rossino R. , Vincis C. , Alves S. , Prata M.J. , Macis M.D. , Nucaro A.L. , Schirru E. , Congia M.
      J. Clin. Pharm. Ther.31:283-287(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPMT DEFICIENCY PRO-80; THR-154 AND CYS-240;FREQUENCY AND DISTRIBUTION OF ALLELES
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