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Index > Protein center > TNFRSF13B(Gene name) > Human
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  • TNFRSF13B (Gene name),
  • Tumor necrosis factor receptor superfamily member 13B (Protein name ),  TR13B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TNFRSF13B(TACI);
    Protein name:
    Tumor necrosis factor receptor superfamily member 13B;
    Alternative:
    Transmembrane activator and CAML interactor;
    CD:
    CD267;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds TRAF2, TRAF5 and TRAF6. Binds the NH2-terminal domain of CAMLG with its C-terminus.
    Function:
    Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
    Subcellular Location:
    Membrane Single-pass type III membrane protein
    Protein Attributes:
    Sequence length:
    293
    Sequence:
    50:
    MSGLGRSRRG | GRSRVDQEER | FPQGLWTGVA | MRSCPEEQYW | DPLLGTCMSC | 
    100:
    KTICNHQSQR | TCAAFCRSLS | CRKEQGKFYD | HLLRDCISCA | SICGQHPKQC | 
    150:
    AYFCENKLRS | PVNLPPELRR | QRSGEVENNS | DNSGRYQGLE | HRGSEASPAL | 
    200:
    PGLKLSADQV | ALVYSTLGLC | LCAVLCCFLV | AVACFLKKRG | DPCSCQPRSR | 
    250:
    PRQSPAKSSQ | DHAMEAGSPV | STSPEPVETC | SFCFPECRAP | TQESAVTPGT | 
    293:
    PDPTCAGRWG | CHTRTTVLQP | CPHIPDSGLG | IVCVPAQEGG | PGA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    UniGene:
    KEGG:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 13B
    Cat.:
    E1627h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 13B
    Cat.:
    E1627m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 13B
    Cat.:
    U1627m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 13B
    Cat.:
    U1627h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13B
    Cat.:
    P1627Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13B
    Cat.:
    P1627Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13B
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13B
    Protein for Human Tumor necrosis factor receptor superfamily member 13B
    Protein for Human Tumor necrosis factor receptor superfamily member 13B

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily."
      von Buelow G.-U. , Bram R.J.
      Science278:138-141(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: B-cell.
    2. 2.
      Zhou G. , Ke R. , Li H. , Zheng G. , Shen C. , Lin L. , Yang S.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);VARIANT LEU-251
      tissue: Spleen.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    6. 6.
      "Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS."
      Wu Y. , Bressette D. , Carrell J.A. , Kaufman T. , Feng P. , Taylor K. , Gan Y. , Cho Y.H. , Garcia A.D. , Gollatz E. , Dimke D. , LaFleur D. , Migone T.S. , Nardelli B. , Wei P. , Ruben S.M. , Ullrich S.J. , Olsen H.S. , more...
      J. Biol. Chem.275:35478-35485(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity."
      Yu G. , Boone T. , Delaney J. , Hawkins N. , Kelley M.J. , Ramakrishnan M. , McCabe S. , Qiu W.R. , Kornuc M. , Xia X.-Z. , Guo J. , Stolina M. , Boyle W.J. , Sarosi I. , Hsu H. , Senaldi G. , Theill L.E.
      Nat. Immunol.1:252-256(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation."
      Xia X.-Z. , Treanor J. , Senaldi G. , Khare S.D. , Boone T. , Kelley M. , Theill L.E. , Colombero A. , Solovyev I. , Lee F. , McCabe S. , Elliott R. , Miner K. , Hawkins N. , Guo J. , Stolina M. , Yu G. , Wang J. , more...
      J. Exp. Med.192:137-143(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF2 AND TRAF5
    9. 9.
      "Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding."
      Hymowitz S.G. , Patel D.R. , Wallweber H.J. , Runyon S. , Yan M. , Yin J. , Shriver S.K. , Gordon N.C. , Pan B. , Skelton N.J. , Kelley R.F. , Starovasnik M.A.
      J. Biol. Chem.280:7218-7227(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 68-109 IN COMPLEX WITH MOUSE TNFSF13;STRUCTURE BY NMR OF 68-109
    10. 10.
      "TACI is mutant in common variable immunodeficiency and IgA deficiency."
      Castigli E. , Wilson S.A. , Garibyan L. , Rachid R. , Bonilla F. , Schneider L. , Geha R.S.
      Nat. Genet.37:829-834(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IGAD2 ARG-104;VARIANTS CVID2 ARG-104; GLY-181 AND HIS-202
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-56
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