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Index > Protein center > TNFRSF13C(Gene name) > Human
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  • TNFRSF13C (Gene name),
  • Tumor necrosis factor receptor superfamily member 13C (Protein name ),  TR13C_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TNFRSF13C(BAFFR;BR3);
    Protein name:
    Tumor necrosis factor receptor superfamily member 13C;
    Alternative:
    BAFF receptor(BAFF-R);B-cell-activating factor receptor;BLyS receptor 3;
    CD:
    CD268;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
    Subcellular Location:
    Membrane Single-pass type III membrane protein
    Protein Attributes:
    Sequence length:
    184
    Sequence:
    50:
    MRRGPRSLRG | RDAPAPTPCV | PAECFDLLVR | HCVACGLLRT | PRPKPAGASS | 
    100:
    PAPRTALQPQ | ESVGAGAGEA | ALPLPGLLFG | APALLGLALV | LALVLVGLVS | 
    150:
    WRRRQRRLRG | ASSAEAPDGD | KDAPEPLDKV | IILSPGISDA | TAPAWPPPGE | 
    184:
    DPGTTPPGHS | VPVPATELGS | TELVTTKTAG | PEQQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 13C
    Cat.:
    E0281h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Tumor necrosis factor receptor superfamily member 13C
    Cat.:
    E0281m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 13C
    Cat.:
    U0281m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor receptor superfamily member 13C
    Cat.:
    U0281h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13C
    Cat.:
    P0281Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13C
    Cat.:
    P0281Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13C
    Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13C
    Protein for Human Tumor necrosis factor receptor superfamily member 13C
    Protein for Human Tumor necrosis factor receptor superfamily member 13C

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: B-cell lymphoma.
    2. 2.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency."
      Yan M. , Brady J.R. , Chan B. , Lee W.P. , Hsu B. , Harless S.M. , Cancro M.P. , Grewal I.S. , Dixit V.M.
      Curr. Biol.11:1547-1552(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    4. 4.
      "BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2."
      Kayagaki N. , Yan M. , Seshasayee D. , Wang H. , Lee W. , French D.M. , Grewal I.S. , Cochran A.G. , Gordon N.C. , Yin J. , Starovasnik M.A. , Dixit V.M.
      Immunity17:515-524(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 26-33;FUNCTION;DISULFIDE BONDS
    5. 5.
      "BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site."
      Gordon N.C. , Pan B. , Hymowitz S.G. , Yin J. , Kelley R.F. , Cochran A.G. , Yan M. , Dixit V.M. , Fairbrother W.J. , Starovasnik M.A.
      Biochemistry42:5977-5983(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-61;X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 26-31 IN COMPLEX WITH TNFSF13B/TALL1/BAFF/BLYS;DISULFIDE BONDS;MUTAGENESIS OF ASP-26 AND LEU-28
    6. 6.
      "Ligand-receptor binding revealed by the TNF family member TALL-1."
      Liu Y. , Hong X. , Kappler J. , Jiang L. , Zhang R. , Xu L. , Pan C.-H. , Martin W.E. , Murphy R.C. , Shu H.-B. , Dai S. , Zhang G.
      Nature423:49-56(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 16-46 IN COMPLEX WITH TNFSF13B/TALL1/BAFF/BLYS;DISULFIDE BONDS;MUTAGENESIS OF CYS-24 AND CYS-35
    7. 7.
      "Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation."
      Kim H.M. , Yu K.S. , Lee M.E. , Shin D.R. , Kim Y.S. , Paik S.-G. , Yoo O.J. , Lee H. , Lee J.-O.
      Nat. Struct. Biol.10:342-348(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF 1-63 IN COMPLEX WITH TNFSF13B/TALL1/BAFF/BLYS;DISULFIDE BONDS
    8. 8.
      "Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells."
      Lee C.V. , Hymowitz S.G. , Wallweber H.J. , Gordon N.C. , Billeci K.L. , Tsai S.-P. , Compaan D.M. , Yin J. , Gong Q. , Kelley R.F. , DeForge L.E. , Martin F. , Starovasnik M.A. , Fuh G.
      Blood108:3103-3111(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.61 ANGSTROMS) OF 7-54;INTERACTION WITH TNFSF13B/TALL1/BAFF/BLYS
    9. 9.
      "Mutational analysis of human BAFF receptor TNFRSF13C (BAFF-R) in patients with common variable immunodeficiency."
      Losi C.G. , Silini A. , Fiorini C. , Soresina A. , Meini A. , Ferrari S. , Notarangelo L.D. , Lougaris V. , Plebani A.
      J. Clin. Immunol.25:496-502(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS VAL-64 AND TYR-159
    10. 10.
      "B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans."
      Warnatz K. , Salzer U. , Rizzi M. , Fischer B. , Gutenberger S. , Boehm J. , Kienzler A.-K. , Pan-Hammarstroem Q. , Hammarstroem L. , Rakhmanov M. , Schlesier M. , Grimbacher B. , Peter H.-H. , Eibel H.
      Proc. Natl. Acad. Sci. U.S.A.106:13945-13950(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CVID4 65-ALA--LEU-72 DELINS VAL;CHARACTERIZATION OF VARIANT CVID4 65-ALA--LEU-72 DELINS VAL
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