Gene name:
TNFRSF13C (BAFFR;BR3) ;
Protein name:
Tumor necrosis factor receptor superfamily member 13C ;
Alternative:
BAFF receptor (BAFF-R) ;B-cell-activating factor receptor ;BLyS receptor 3 ;
CD:
CD268 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
Subcellular Location:
Membrane
Single-pass type III membrane protein
Protein Attributes:
50:
MRRGPRSLRG | RDAPAPTPCV | PAECFDLLVR | HCVACGLLRT | PRPKPAGASS |
100:
PAPRTALQPQ | ESVGAGAGEA | ALPLPGLLFG | APALLGLALV | LALVLVGLVS |
150:
WRRRQRRLRG | ASSAEAPDGD | KDAPEPLDKV | IILSPGISDA | TAPAWPPPGE |
184:
DPGTTPPGHS | VPVPATELGS | TELVTTKTAG | PEQQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Tumor necrosis factor receptor superfamily member 13C
ELISA Kit for Human Tumor necrosis factor receptor superfamily member 13C
CLIA Kit for Human Tumor necrosis factor receptor superfamily member 13C
CLIA Kit for Human Tumor necrosis factor receptor superfamily member 13C
Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13C
Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13C
Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13C
Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 13C
Protein for Human Tumor necrosis factor receptor superfamily member 13C
Protein for Human Tumor necrosis factor receptor superfamily member 13C
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue :
B-cell lymphoma .
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more...
Nature402:489-495(1999)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
4.
"BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2."
Kayagaki N.
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Yan M.
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PubMed ]
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 26-33;FUNCTION;DISULFIDE BONDS
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 1-61;X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 26-31 IN COMPLEX WITH TNFSF13B/TALL1/BAFF/BLYS;DISULFIDE BONDS;MUTAGENESIS OF ASP-26 AND LEU-28
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Nature423:49-56(2003)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 16-46 IN COMPLEX WITH TNFSF13B/TALL1/BAFF/BLYS;DISULFIDE BONDS;MUTAGENESIS OF CYS-24 AND CYS-35
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF 1-63 IN COMPLEX WITH TNFSF13B/TALL1/BAFF/BLYS;DISULFIDE BONDS
8.
"Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells."
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Blood108:3103-3111(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.61 ANGSTROMS) OF 7-54;INTERACTION WITH TNFSF13B/TALL1/BAFF/BLYS
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS VAL-64 AND TYR-159
10.
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Proc. Natl. Acad. Sci. U.S.A.106:13945-13950(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT CVID4 65-ALA--LEU-72 DELINS VAL;CHARACTERIZATION OF VARIANT CVID4 65-ALA--LEU-72 DELINS VAL