Protein name:
TNF receptor-associated factor 6 ;
Alternative:
Interleukin-1 signal transducer ;E3 ubiquitin-protein ligase TRAF6 ;RING finger protein 85 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homotrimer. Homooligomer. N-terminal region is dimeric while C-terminal region is trimeric; maybe providing a mode of oligomerization. Binds to TNFRSF5/CD40 and TNFRSF11A/RANK. Associates with NGFR, TNFRSF17, IRAK1, IRAK2, IRAK3, IRAK4, RIPK2, MAP3K1, MAP3K5, MAP3K14, CSK, TRAF, TRAF-interacting protein TRIP and TNF receptor associated protein TDP2. Interacts with IL17R. Interacts with SQSTM1 bridging NTRK1 and NGFR. Forms a ternary complex with SQSTM1 and PRKCZ (By similarity). Interacts with PELI1, PELI2 and PELI3. Binds UBE2V1. Interacts with MAVS/IPS1. Interacts with TAX1BP1. Interacts with IL1RL1. Interacts with TRAFD1. Interacts with ZNF675. Interacts with JUB. Interacts with TICAM1 and TICAM2. Interacts with ZFAND5. Interacts with ARRB1 and ARRB2. Interacts with MAP3K7 and TAB1/MAP3K7IP1; during IL-1 signaling. Interacts with UBE2N. Interacts with TGFBR1, HDAC1 and RANGAP1. Interacts with AKT1, AKT2 and AKT3. Interacts (via TRAF domains) with NUMBL (via C-terminal). Interacts (via TRAF domains) with WDR34 (via WD domains). Interacts with RBCK1.
Function:
E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor.
Subcellular Location:
Cytoplasm
Cytoplasm
cell cortex
Nucleus
Found in the nuclei of some agressive B-cell lymphoma cell lines as well as in the nuclei of both resting and activated T-and B-lymphocytes. Found in punctate nuclear body protein complexes. Ubiquitination may occur in the cytoplasm and sumoylation in the nucleus.
Protein Attributes:
50:
MSLLNCENSC | GSSQSESDCC | VAMASSCSAV | TKDDSVGGTA | STGNLSSSFM |
100:
EEIQGYDVEF | DPPLESKYEC | PICLMALREA | VQTPCGHRFC | KACIIKSIRD |
150:
AGHKCPVDNE | ILLENQLFPD | NFAKREILSL | MVKCPNEGCL | HKMELRHLED |
200:
HQAHCEFALM | DCPQCQRPFQ | KFHINIHILK | DCPRRQVSCD | NCAASMAFED |
250:
KEIHDQNCPL | ANVICEYCNT | ILIREQMPNH | YDLDCPTAPI | PCTFSTFGCH |
300:
EKMQRNHLAR | HLQENTQSHM | RMLAQAVHSL | SVIPDSGYIS | EVRNFQETIH |
350:
QLEGRLVRQD | HQIRELTAKM | ETQSMYVSEL | KRTIRTLEDK | VAEIEAQQCN |
400:
GIYIWKIGNF | GMHLKCQEEE | KPVVIHSPGF | YTGKPGYKLC | MRLHLQLPTA |
450:
QRCANYISLF | VHTMQGEYDS | HLPWPFQGTI | RLTILDQSEA | PVRQNHEEIM |
500:
DAKPELLAFQ | RPTIPRNPKG | FGYVTFMHLE | ALRQRTFIKD | DTLLVRCEVS |
522:
TRFDMGSLRR | EGFQPRSTDA | GV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Pig
Bovine
ELISA Kit for Human TNF receptor-associated factor 6
ELISA Kit for Human TNF receptor-associated factor 6
ELISA Kit for Human TNF receptor-associated factor 6
ELISA Kit for Human TNF receptor-associated factor 6
ELISA Kit for Human TNF receptor-associated factor 6
CLIA Kit for Human TNF receptor-associated factor 6
CLIA Kit for Human TNF receptor-associated factor 6
CLIA Kit for Human TNF receptor-associated factor 6
CLIA Kit for Human TNF receptor-associated factor 6
CLIA Kit for Human TNF receptor-associated factor 6
Polyclonal Antibody for Human TNF receptor-associated factor 6
Polyclonal Antibody for Human TNF receptor-associated factor 6
Polyclonal Antibody for Human TNF receptor-associated factor 6
Polyclonal Antibody for Human TNF receptor-associated factor 6
Polyclonal Antibody for Human TNF receptor-associated factor 6
Monoclonal Antibody for Human TNF receptor-associated factor 6
Monoclonal Antibody for Human TNF receptor-associated factor 6
Monoclonal Antibody for Human TNF receptor-associated factor 6
Monoclonal Antibody for Human TNF receptor-associated factor 6
Monoclonal Antibody for Human TNF receptor-associated factor 6
Protein for Human TNF receptor-associated factor 6
Protein for Human TNF receptor-associated factor 6
Protein for Human TNF receptor-associated factor 6
Protein for Human TNF receptor-associated factor 6
Protein for Human TNF receptor-associated factor 6
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH IRAK1
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
,
Suzuki Y.
,
Nishikawa T.
,
Otsuki T.
,
Sugiyama T.
,
Irie R.
,
Wakamatsu A.
,
Hayashi K.
,
Sato H.
,
Nagai K.
,
Kimura K.
,
Makita H.
,
Sekine M.
,
Obayashi M.
,
Nishi T.
,
Shibahara T.
,
Tanaka T.
,
Ishii S.
,
Yamamoto J.
,
Saito K.
,
Kawai Y.
,
Isono Y.
,
Nakamura Y.
,
Nagahari K.
,
Murakami K.
,
Yasuda T.
,
Iwayanagi T.
,
Wagatsuma M.
,
Shiratori A.
,
Sudo H.
,
Hosoiri T.
,
Kaku Y.
,
Kodaira H.
,
Kondo H.
,
Sugawara M.
,
Takahashi M.
,
Kanda K.
,
Yokoi T.
,
Furuya T.
,
Kikkawa E.
,
Omura Y.
,
Abe K.
,
Kamihara K.
,
Katsuta N.
,
Sato K.
,
Tanikawa M.
,
Yamazaki M.
,
Ninomiya K.
,
Ishibashi T.
,
Yamashita H.
,
Murakawa K.
,
Fujimori K.
,
Tanai H.
,
Kimata M.
,
Watanabe M.
,
Hiraoka S.
,
Chiba Y.
,
Ishida S.
,
Ono Y.
,
Takiguchi S.
,
Watanabe S.
,
Yosida M.
,
Hotuta T.
,
Kusano J.
,
Kanehori K.
,
Takahashi-Fujii A.
,
Hara H.
,
Tanase T.-O.
,
Nomura Y.
,
Togiya S.
,
Komai F.
,
Hara R.
,
Takeuchi K.
,
Arita M.
,
Imose N.
,
Musashino K.
,
Yuuki H.
,
Oshima A.
,
Sasaki N.
,
Aotsuka S.
,
Yoshikawa Y.
,
Matsunawa H.
,
Ichihara T.
,
Shiohata N.
,
Sano S.
,
Moriya S.
,
Momiyama H.
,
Satoh N.
,
Takami S.
,
Terashima Y.
,
Suzuki O.
,
Nakagawa S.
,
Senoh A.
,
Mizoguchi H.
,
Goto Y.
,
Shimizu F.
,
Wakebe H.
,
Hishigaki H.
,
Watanabe T.
,
Sugiyama A.
,
Takemoto M.
,
Kawakami B.
,
Yamazaki M.
,
Watanabe K.
,
Kumagai A.
,
Itakura S.
,
Fukuzumi Y.
,
Fujimori Y.
,
Komiyama M.
,
Tashiro H.
,
Tanigami A.
,
Fujiwara T.
,
Ono T.
,
Yamada K.
,
Fujii Y.
,
Ozaki K.
,
Hirao M.
,
Ohmori Y.
,
Kawabata A.
,
Hikiji T.
,
Kobatake N.
,
Inagaki H.
,
Ikema Y.
,
Okamoto S.
,
Okitani R.
,
Kawakami T.
,
Noguchi S.
,
Itoh T.
,
Shigeta K.
,
Senba T.
,
Matsumura K.
,
Nakajima Y.
,
Mizuno T.
,
Morinaga M.
,
Sasaki M.
,
Togashi T.
,
Oyama M.
,
Hata H.
,
Watanabe M.
,
Komatsu T.
,
Mizushima-Sugano J.
,
Satoh T.
,
Shirai Y.
,
Takahashi Y.
,
Nakagawa K.
,
Okumura K.
,
Nagase T.
,
Nomura N.
,
Kikuchi H.
,
Masuho Y.
,
Yamashita R.
,
Nakai K.
,
Yada T.
,
Nakamura Y.
,
Ohara O.
,
Isogai T.
,
Sugano S.
more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Trachea .
4.
"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D.
,
Noguchi H.
,
Totoki Y.
,
Toyoda A.
,
Kuroki Y.
,
Dewar K.
,
Lloyd C.
,
Itoh T.
,
Takeda T.
,
Kim D.-W.
,
She X.
,
Barlow K.F.
,
Bloom T.
,
Bruford E.
,
Chang J.L.
,
Cuomo C.A.
,
Eichler E.
,
FitzGerald M.G.
,
Jaffe D.B.
,
LaButti K.
,
Nicol R.
,
Park H.-S.
,
Seaman C.
,
Sougnez C.
,
Yang X.
,
Zimmer A.R.
,
Zody M.C.
,
Birren B.W.
,
Nusbaum C.
,
Fujiyama A.
,
Hattori M.
,
Rogers J.
,
Lander E.S.
,
Sakaki Y.
more...
Nature440:497-500(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAP3K14
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH IRAK2
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH RIPK2
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TNFRSF11A
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TNFRSF5
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAP3K5
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAP3K1
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NGFR
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH IRAK3
16.
"TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction."
Ye X.
,
Mehlen P.
,
Rabizadeh S.
,
VanArsdale T.
,
Zhang H.
,
Shin H.
,
Wang J.J.L.
,
Leo E.
,
Zapata J.M.
,
Hauser C.A.
,
Reed J.C.
,
Bredesen D.E.
J. Biol. Chem.274:30202-30208(1999)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NGFR
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TNFRSF11A AND CSK
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAP3K7 AND TAB1
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAP3K5
20.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH UBE2V1;FUNCTION AS AN E3 UBIQUITIN LIGASE
21.
"TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation."
Pype S.
,
Declercq W.
,
Ibrahimi A.
,
Michiels C.
,
Van Rietschoten J.G.I.
,
Dewulf N.
,
de Boer M.
,
Vandenabeele P.
,
Huylebroeck D.
,
Remacle J.E.
J. Biol. Chem.275:18586-18593(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TDP2
22.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TNFRSF17
23.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TAX1BP1
24.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : UBIQUITINATION
25.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TRAF3IP2
26.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ZNF675
27.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH IRAK4
28.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PELI1
29.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PELI1 AND PELI2
30.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TICAM2
31.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PELI3
32.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TICAM1
33.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TICAM1
34.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ZFAND5
35.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH EIF2AK2
36.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TICAM1
37.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAVS
38.
"IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST 2 and induces T helper type 2-associated cytokines."
Schmitz J.
,
Owyang A.
,
Oldham E.
,
Song Y.
,
Murphy E.
,
McClanahan T.K.
,
Zurawski G.
,
Moshrefi M.
,
Qin J.
,
Li X.
,
Gorman D.M.
,
Bazan J.F.
,
Kastelein R.A.
Immunity23:479-490(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH IL1RL1
39.
"FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling."
Mashima R.
,
Saeki K.
,
Aki D.
,
Minoda Y.
,
Takaki H.
,
Sanada T.
,
Kobayashi T.
,
Aburatani H.
,
Yamanashi Y.
,
Yoshimura A.
J. Biol. Chem.280:41289-41297(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TRAFD1
40.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAVS
41.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH AJUBA
42.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN TRANSCRIPTIONAL ACTIVATION OF NF-KAPPA-B AND JUN;INTERACTION WITH ARBB1 AND ARBB2
43.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN COMPLEX WITH IRAK1; IRAK4; MYD88 AND PELI1
44.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : MUTAGENESIS OF CYS-70 AND LYS-124;UBIQUITINATION AT LYS-124;FUNCTION
45.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH RBCK1
46.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;FUNCTION;SUMOYLATION AT LYS-124; LYS-142 AND LYS-453;UBIQUITINATION;INTERACTION WITH HDAC1 AND RANGAP1;MUTAGENESIS OF LYS-124; LYS-142 AND LYS-453
47.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN UBIQUITINATION OR IRAK1
48.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH TGFBR1;UBIQUITINATION
49.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH WDR34
50.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;UBIQUITINATION
51.
"The E3 ligase TRAF6 regulates Akt ubiquitination and activation."
Yang W.-L.
,
Wang J.
,
Chan C.-H.
,
Lee S.-W.
,
Campos A.D.
,
Lamothe B.
,
Hur L.
,
Grabiner B.C.
,
Lin X.
,
Darnay B.G.
,
Lin H.-K.
Science325:1134-1138(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
52.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NUMBL
53.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CARD14
54.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH IFIT3
55.
"Distinct molecular mechanism for initiating TRAF6 signalling."
Ye H.
,
Arron J.R.
,
Lamothe B.
,
Cirilli M.
,
Kobayashi T.
,
Shevde N.K.
,
Segal D.
,
Dzivenu O.K.
,
Vologodskaia M.
,
Yim M.
,
Du K.
,
Singh S.
,
Pike J.W.
,
Darnay B.G.
,
Choi Y.
,
Wu H.
Nature418:443-447(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 347-506 OF APOPROTEIN AND IN COMPLEXES WITH TNFRSF5 AND TNFRSF11A PEPTIDES;FUNCTION;SUBUNIT
56.
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Cited for : STRUCTURE BY NMR OF 63-124 IN COMPLEX WITH ZINC IONS;INTERACTION WITH UBE2N
57.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 43-128
58.
"E2 interaction and dimerization in the crystal structure of TRAF6."
Yin Q.
,
Lin S.C.
,
Lamothe B.
,
Lu M.
,
Lo Y.C.
,
Hura G.
,
Zheng L.
,
Rich R.L.
,
Campos A.D.
,
Myszka D.G.
,
Lenardo M.J.
,
Darnay B.G.
,
Wu H.
Nat. Struct. Mol. Biol.16:658-666(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 50-211 IN COMPLEXES WITH ZINC IONS AND UBE2N;SUBUNIT;FUNCTION;AUTOUBIQUITINATION;MUTAGENESIS OF ASP-57; CYS-70; ILE-72; LEU-74; ARG-88; PHE-118; PHE-122 AND LYS-124;ZINC-FINGER