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Index > Protein center > TREM2(Gene name) > Human
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  • TREM2 (Gene name),
  • Triggering receptor expressed on myeloid cells 2 (Protein name ),  TREM2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TREM2;
    Protein name:
    Triggering receptor expressed on myeloid cells 2(TREM-2);
    Alternative:
    Triggering receptor expressed on monocytes 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with TYROBP/DAP12.
    Function:
    May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
    Subcellular Location:
    Isoform 3 Secreted
    Protein Attributes:
    Sequence length:
    230
    Sequence:
    50:
    MEPLRLLILL | FVTELSGAHN | TTVFQGVAGQ | SLQVSCPYDS | MKHWGRRKAW | 
    100:
    CRQLGEKGPC | QRVVSTHNLW | LLSFLRRWNG | STAITDDTLG | GTLTITLRNL | 
    150:
    QPHDAGLYQC | QSLHGSEADT | LRKVLVEVLA | DPLDHRDAGD | LWFPGESESF | 
    200:
    EDAHVEHSIS | RSLLEGEIPF | PPTSILLLLA | CIFLIKILAA | SALWAAAWHG | 
    230:
    QKPGTHPPSE | LDCGHDPGYQ | LQTLPGLRDT | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    MIM:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human TREM-2
    Cat.:
    E12753m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human TREM-2
    Cat.:
    E12753h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human TREM-2
    Cat.:
    U12753h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human TREM-2
    Cat.:
    U12753m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human TREM-2
    Polyclonal Antibody for Human TREM-2
    Cat.:
    P12753Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human TREM-2
    Monoclonal Antibody for Human TREM-2
    Protein for Human TREM-2
    Protein for Human TREM-2

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes."
      Bouchon A. , Dietrich J. , Colonna M.
      J. Immunol.164:4991-4995(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
    2. 2.
      "Identification of a novel variant of triggering receptor, TREM-2V, by mRNA differential display."
      Begum N.A. , Tsukasa S.
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Brain.
    4. 4.
      "Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype."
      Paloneva J. , Manninen T. , Christman G. , Hovanes K. , Mandelin J. , Adolfsson R. , Bianchin M. , Bird T. , Miranda R. , Salmaggi A. , Tranebjaerg L. , Konttinen Y. , Peltonen L.
      Am. J. Hum. Genet.71:656-662(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;VARIANTS PLOSL GLY-134 AND ASN-186
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
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