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Index > Protein center > TRH(Gene name) > Human
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  • TRH (Gene name),
  • Prothyroliberin (Protein name ),  TRH_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TRH;
    Protein name:
    Prothyroliberin(Pro-TRH);
    Alternative:
    Prothyroliberin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    242
    Sequence:
    50:
    MPGPWLLLAL | ALTLNLTGVP | GGRAQPEAAQ | QEAVTAAEHP | GLDDFLRQVE | 
    100:
    RLLFLRENIQ | RLQGDQGEHS | ASQIFQSDWL | SKRQHPGKRE | EEEEEGVEEE | 
    150:
    EEEEGGAVGP | HKRQHPGRRE | DEASWSVDVT | QHKRQHPGRR | SPWLAYAVPK | 
    200:
    RQHPGRRLAD | PKAQRSWEEE | EEEEEREEDL | MPEKRQHPGK | RALGGPCGPQ | 
    242:
    GAYGQAGLLL | GLLDDLSRSQ | GAEEKRQHPG | RRAAWVREPL | EE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Pro-TRH
    Cat.:
    E0839r
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    96T
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    ELISA Kit for Human Pro-TRH
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    E0839p
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    ELISA Kit for Human Pro-TRH
    Cat.:
    E0839h
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    96T
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    ELISA Kit for Human Pro-TRH
    Cat.:
    E0839c
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    96T
    ELISA Kit for Human Pro-TRH
    Cat.:
    E0839m
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    Packing:
    96T
    CLIA Kit for Human Pro-TRH
    Cat.:
    U0839p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Pro-TRH
    Cat.:
    U0839h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Pro-TRH
    Cat.:
    U0839c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Pro-TRH
    Cat.:
    U0839m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Pro-TRH
    Cat.:
    U0839r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Pro-TRH
    Cat.:
    P0839Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Pro-TRH
    Cat.:
    P0839Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Pro-TRH
    Polyclonal Antibody for Human Pro-TRH
    Cat.:
    P0839Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Pro-TRH
    Monoclonal Antibody for Human Pro-TRH
    Monoclonal Antibody for Human Pro-TRH
    Monoclonal Antibody for Human Pro-TRH
    Monoclonal Antibody for Human Pro-TRH
    Monoclonal Antibody for Human Pro-TRH
    Protein for Human Pro-TRH
    Protein for Human Pro-TRH
    Protein for Human Pro-TRH
    Protein for Human Pro-TRH
    Protein for Human Pro-TRH

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    References
    1. 1.
      "Cloning and structure of human genomic DNA and hypothalamic cDNA encoding human prepro thyrotropin-releasing hormone."
      Yamada M. , Radovick S. , Wondisford F.E. , Nakayama Y. , Weintraub B.D. , Wilber J.F.
      Mol. Endocrinol.4:551-556(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Subthalamic nucleus.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    5. 5.
      "Thyrotropin releasing hormone (TRH): a new player in human hair-growth control."
      Gaspar E. , Hardenbicker C. , Bodo E. , Wenzel B. , Ramot Y. , Funk W. , Kromminga A. , Paus R.
      FASEB J.24:393-403(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
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