"Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens."
Emi M. , Nakamura Y. , Ogawa M. , Yamamoto T. , Nishide T. , Mori T. , Matsubara K.
Gene41:305-310(1986) [PubMed] [Europe PMC] [Abstract]

"The complete 685-kilobase DNA sequence of the human beta T cell receptor locus."
Rowen L. , Koop B.F. , Hood L.
Science272:1755-1762(1996) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , Yamamoto J. , Saito K. , Kawai Y. , Isono Y. , Nakamura Y. , Nagahari K. , Murakami K. , Yasuda T. , Iwayanagi T. , Wagatsuma M. , Shiratori A. , Sudo H. , Hosoiri T. , Kaku Y. , Kodaira H. , Kondo H. , Sugawara M. , Takahashi M. , Kanda K. , Yokoi T. , Furuya T. , Kikkawa E. , Omura Y. , Abe K. , Kamihara K. , Katsuta N. , Sato K. , Tanikawa M. , Yamazaki M. , Ninomiya K. , Ishibashi T. , Yamashita H. , Murakawa K. , Fujimori K. , Tanai H. , Kimata M. , Watanabe M. , Hiraoka S. , Chiba Y. , Ishida S. , Ono Y. , Takiguchi S. , Watanabe S. , Yosida M. , Hotuta T. , Kusano J. , Kanehori K. , Takahashi-Fujii A. , Hara H. , Tanase T.-O. , Nomura Y. , Togiya S. , Komai F. , Hara R. , Takeuchi K. , Arita M. , Imose N. , Musashino K. , Yuuki H. , Oshima A. , Sasaki N. , Aotsuka S. , Yoshikawa Y. , Matsunawa H. , Ichihara T. , Shiohata N. , Sano S. , Moriya S. , Momiyama H. , Satoh N. , Takami S. , Terashima Y. , Suzuki O. , Nakagawa S. , Senoh A. , Mizoguchi H. , Goto Y. , Shimizu F. , Wakebe H. , Hishigaki H. , Watanabe T. , Sugiyama A. , Takemoto M. , Kawakami B. , Yamazaki M. , Watanabe K. , Kumagai A. , Itakura S. , Fukuzumi Y. , Fujimori Y. , Komiyama M. , Tashiro H. , Tanigami A. , Fujiwara T. , Ono T. , Yamada K. , Fujii Y. , Ozaki K. , Hirao M. , Ohmori Y. , Kawabata A. , Hikiji T. , Kobatake N. , Inagaki H. , Ikema Y. , Okamoto S. , Okitani R. , Kawakami T. , Noguchi S. , Itoh T. , Shigeta K. , Senba T. , Matsumura K. , Nakajima Y. , Mizuno T. , Morinaga M. , Sasaki M. , Togashi T. , Oyama M. , Hata H. , Watanabe M. , Komatsu T. , Mizushima-Sugano J. , Satoh T. , Shirai Y. , Takahashi Y. , Nakagawa K. , Okumura K. , Nagase T. , Nomura N. , Kikuchi H. , Masuho Y. , Yamashita R. , Nakai K. , Yada T. , Nakamura Y. , Ohara O. , Isogai T. , Sugano S. more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Cordes M. , Du H. , Sun H. , Edwards J. , Bradshaw-Cordum H. , Ali J. , Andrews S. , Isak A. , Vanbrunt A. , Nguyen C. , Du F. , Lamar B. , Courtney L. , Kalicki J. , Ozersky P. , Bielicki L. , Scott K. , Holmes A. , Harkins R. , Harris A. , Strong C.M. , Hou S. , Tomlinson C. , Dauphin-Kohlberg S. , Kozlowicz-Reilly A. , Leonard S. , Rohlfing T. , Rock S.M. , Tin-Wollam A.-M. , Abbott A. , Minx P. , Maupin R. , Strowmatt C. , Latreille P. , Miller N. , Johnson D. , Murray J. , Woessner J.P. , Wendl M.C. , Yang S.-P. , Schultz B.R. , Wallis J.W. , Spieth J. , Bieri T.A. , Nelson J.O. , Berkowicz N. , Wohldmann P.E. , Cook L.L. , Hickenbotham M.T. , Eldred J. , Williams D. , Bedell J.A. , Mardis E.R. , Clifton S.W. , Chissoe S.L. , Marra M.A. , Raymond C. , Haugen E. , Gillett W. , Zhou Y. , James R. , Phelps K. , Iadanoto S. , Bubb K. , Simms E. , Levy R. , Clendenning J. , Kaul R. , Kent W.J. , Furey T.S. , Baertsch R.A. , Brent M.R. , Keibler E. , Flicek P. , Bork P. , Suyama M. , Bailey J.A. , Portnoy M.E. , Torrents D. , Chinwalla A.T. , Gish W.R. , Eddy S.R. , McPherson J.D. , Olson M.V. , Eichler E.E. , Green E.D. , Waterston R.H. , Wilson R.K. more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 7: DNA sequence and biology."
Scherer S.W. , Cheung J. , MacDonald J.R. , Osborne L.R. , Nakabayashi K. , Herbrick J.-A. , Carson A.R. , Parker-Katiraee L. , Skaug J. , Khaja R. , Zhang J. , Hudek A.K. , Li M. , Haddad M. , Duggan G.E. , Fernandez B.A. , Kanematsu E. , Gentles S. , Christopoulos C.C. , Choufani S. , Kwasnicka D. , Zheng X.H. , Lai Z. , Nusskern D.R. , Zhang Q. , Gu Z. , Lu F. , Zeesman S. , Nowaczyk M.J. , Teshima I. , Chitayat D. , Shuman C. , Weksberg R. , Zackai E.H. , Grebe T.A. , Cox S.R. , Kirkpatrick S.J. , Rahman N. , Friedman J.M. , Heng H.H.Q. , Pelicci P.G. , Lo-Coco F. , Belloni E. , Shaffer L.G. , Pober B. , Morton C.C. , Gusella J.F. , Bruns G.A.P. , Korf B.R. , Quade B.J. , Ligon A.H. , Ferguson H. , Higgins A.W. , Leach N.T. , Herrick S.R. , Lemyre E. , Farra C.G. , Kim H.-G. , Summers A.M. , Gripp K.W. , Roberts W. , Szatmari P. , Winsor E.J.T. , Grzeschik K.-H. , Teebi A. , Minassian B.A. , Kere J. , Armengol L. , Pujana M.A. , Estivill X. , Wilson M.D. , Koop B.F. , Tosi S. , Moore G.E. , Boright A.P. , Zlotorynski E. , Kerem B. , Kroisel P.M. , Petek E. , Oscier D.G. , Mould S.J. , Doehner H. , Doehner K. , Rommens J.M. , Vincent J.B. , Venter J.C. , Li P.W. , Mural R.J. , Adams M.D. , Tsui L.-C. more...
Science300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , Yooseph S. , Lu F. , Nusskern D.R. , Shue B.C. , Zheng X.H. , Zhong F. , Delcher A.L. , Huson D.H. , Kravitz S.A. , Mouchard L. , Reinert K. , Remington K.A. , Clark A.G. , Waterman M.S. , Eichler E.E. , Adams M.D. , Hunkapiller M.W. , Myers E.W. , Venter J.C. more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation."
Teich N. , Ockenga J. , Hoffmeister A. , Manns M. , Mossner J. , Keim V.
Gastroenterology119:461-465(2000) [PubMed] [Europe PMC] [Abstract]

"Identification of one- and two-chain forms of trypsinogen 1 produced by a human gastric adenocarcinoma cell line."
Koshikawa N. , Yasumitsu H. , Nagashima Y. , Umeda M. , Miyazaki K.
Biochem. J.303:187-190(1994) [PubMed] [Europe PMC] [Abstract]

"Immunoreactive anionic and cationic trypsin in human serum."
Kimland M. , Russick C. , Marks W.H. , Borgstroem A.
Clin. Chim. Acta184:31-46(1989) [PubMed] [Europe PMC] [Abstract]

"Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene."
Whitcomb D.C. , Gorry M.C. , Preston R.A. , Furey W. , Sossenheimer M.J. , Ulrich C.D. , Martin S.P. , Gates L.K. Jr. , Amann S.T. , Toskes P.P. , Liddle R. , McGrath K. , Uomo G. , Post J.C. , Ehrlich G.D.
Nat. Genet.14:141-145(1996) [PubMed] [Europe PMC] [Abstract]

"Mutational screening of patients with nonalcoholic chronic pancreatitis: identification of further trypsinogen variants."
Teich N. , Bauer N. , Mossner J. , Keim V.
Am. J. Gastroenterol.97:341-346(2002) [PubMed] [Europe PMC] [Abstract]

Lubec G. , Afjehi-Sadat L.
Submitted (2007-03) to the UniProtKB

"Human cationic trypsinogen is sulfated on Tyr154."
Sahin-Toth M. , Kukor Z. , Nemoda Z.
FEBS J.273:5044-5050(2006) [PubMed] [Europe PMC] [Abstract]

"Tyrosine sulfation of human trypsin steers S2' subsite selectivity towards basic amino acids."
Szabo A. , Salameh M.A. , Ludwig M. , Radisky E.S. , Sahin-Toth M.
PLoS ONE9:E102063-E102063(2014) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of human trypsin 1: unexpected phosphorylation of Tyr151."
Gaboriaud C. , Serre L. , Guy-Crotte O. , Forest E. , Fontecilla-Camps J.-C.
J. Mol. Biol.259:995-1010(1996) [PubMed] [Europe PMC] [Abstract]

"Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis."
Gorry M.C. , Gabbaizedeh D. , Furey W. , Gates L.K. Jr. , Preston R.A. , Aston C.E. , Zhang Y. , Ulrich C. , Ehrlich G.D. , Whitcomb D.C.
Gastroenterology113:1063-1068(1997) [PubMed] [Europe PMC] [Abstract]

"Mutations of the cationic trypsinogen in hereditary pancreatitis."
Teich N. , Mossner J. , Keim V.
Hum. Mutat.12:39-43(1998) [PubMed] [Europe PMC] [Abstract]

"A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis."
Witt H. , Luck W. , Becker M.
Gastroenterology117:7-10(1999) [PubMed] [Europe PMC] [Abstract]

"Mutations in the cationic trypsinogen gene and evidence for genetic heterogeneity in hereditary pancreatitis."
Ferec C. , Raguenes O. , Salomon R. , Roche C. , Bernard J.P. , Guillot M. , Quere I. , Faure C. , Mercier B. , Audrezet M.-P. , Guillausseau P.J. , Dupont C. , Munnich A. , Bignon J.D. , Le Bodic L.
J. Med. Genet.36:228-232(1999) [PubMed] [Europe PMC] [Abstract]

"A CGC>CAT gene conversion-like event resulting in the R122H mutation in the cationic trypsinogen gene and its implication in the genotyping of pancreatitis."
Chen J.-M. , Raguenes O. , Ferec C. , Deprez P.H. , Verellen-Dumoulin C.
J. Med. Genet.37:E36-E36(2000) [PubMed] [Europe PMC] [Abstract]

"Novel cationic trypsinogen (PRSS1) N29T and R122C mutations cause autosomal dominant hereditary pancreatitis."
Pfutzer R. , Myers E. , Applebaum-Shapiro S. , Finch R. , Ellis I. , Neoptolemos J. , Kant J.A. , Whitcomb D.C.
Gut50:271-272(2002) [PubMed] [Europe PMC] [Abstract]

"Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2)."
Teich N. , Le Marechal C. , Kukor Z. , Caca K. , Witzigmann H. , Chen J.-M. , Toth M. , Moessner J. , Keim V. , Ferec C. , Sahin-Toth M.
Hum. Mutat.23:22-31(2004) [PubMed] [Europe PMC] [Abstract]

"Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl."
Teich N. , Nemoda Z. , Koehler H. , Heinritz W. , Moessner J. , Keim V. , Sahin-Toth M.
Hum. Mutat.25:343-347(2005) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , Gazdar A.F. , Hartigan J. , Wu L. , Liu C. , Parmigiani G. , Park B.H. , Bachman K.E. , Papadopoulos N. , Vogelstein B. , Kinzler K.W. , Velculescu V.E. more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]