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Index > Protein center > TNFAIP6(Gene name) > Human
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  • TNFAIP6 (Gene name),
  • Tumor necrosis factor-inducible gene 6 protein (Protein name ),  TSG6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TNFAIP6(TSG6);
    Protein name:
    Tumor necrosis factor-inducible gene 6 protein;
    Alternative:
    TNF-stimulated gene 6 protein(TSG-6);Hyaluronate-binding protein;Tumor necrosis factor alpha-induced protein 6(TNF alpha-induced protein 6);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with inter-alpha-inhibitor (I-alpha-I). Chondroitin sulfate may be required for the stability of the complex.
    Function:
    Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    277
    Sequence:
    50:
    MIILIYLFLL | LWEDTQGWGF | KDGIFHNSIW | LERAAGVYHR | EARSGKYKLT | 
    100:
    YAEAKAVCEF | EGGHLATYKQ | LEAARKIGFH | VCAAGWMAKG | RVGYPIVKPG | 
    150:
    PNCGFGKTGI | IDYGIRLNRS | ERWDAYCYNP | HAKECGGVFT | DPKQIFKSPG | 
    200:
    FPNEYEDNQI | CYWHIRLKYG | QRIHLSFLDF | DLEDDPGCLA | DYVEIYDSYD | 
    250:
    DVHGFVGRYC | GDELPDDIIS | TGNVMTLKFL | SDASVTAGGF | QIKYVAMDPV | 
    277:
    SKSSQGKNTS | TTSTGNKNFL | AGRFSHL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    MIM:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor-inducible gene 6 protein
    Cat.:
    E0651m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Tumor necrosis factor-inducible gene 6 protein
    Cat.:
    E0651h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Tumor necrosis factor-inducible gene 6 protein
    MSDS:
    Please sign in first.
    CLIA Kit for Human Tumor necrosis factor-inducible gene 6 protein
    Cat.:
    U0651h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Tumor necrosis factor-inducible gene 6 protein
    Cat.:
    U0651m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Tumor necrosis factor-inducible gene 6 protein
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human Tumor necrosis factor-inducible gene 6 protein
    Polyclonal Antibody for Human Tumor necrosis factor-inducible gene 6 protein
    Cat.:
    P0651Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor-inducible gene 6 protein
    Cat.:
    P0651Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tumor necrosis factor-inducible gene 6 protein
    Monoclonal Antibody for Human Tumor necrosis factor-inducible gene 6 protein
    Monoclonal Antibody for Human Tumor necrosis factor-inducible gene 6 protein
    Protein for Human Tumor necrosis factor-inducible gene 6 protein
    Protein for Human Tumor necrosis factor-inducible gene 6 protein
    Protein for Human Tumor necrosis factor-inducible gene 6 protein

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    Linearity
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    References
    1. 1.
      "A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44."
      Lee T.H. , Wisniewski H.-G. , Vilcek J.
      J. Cell Biol.116:545-557(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ARG-144
      tissue: Fibroblast.
    2. 2.
      "A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression."
      Nentwich H.A. , Mustafa Z. , Rugg M.S. , Marsden B.D. , Cordell M.R. , Mahoney D.J. , Jenkins S.C. , Dowling B. , Fries E. , Milner C.M. , Loughlin J. , Day A.J.
      J. Biol. Chem.277:15354-15362(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ARG-144
      tissue: Lung.
      tissue: Spleen.
    6. 6.
      "TSG-6, an arthritis-associated hyaluronan binding protein, forms a stable complex with the serum protein inter-alpha-inhibitor."
      Wisniewski H.-G. , Burgess W.H. , Oppenheim J.D. , Vilcek J.
      Biochemistry33:7423-7429(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 18-27;TISSUE SPECIFICITY;INTERACTION WITH INTER-ALPHA-INHIBITOR
    7. 7.
      "Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration."
      Kohda D. , Morton C.J. , Parkar A.A. , Hatanaka H. , Inagaki F.M. , Campbell I.D. , Day A.J.
      Cell86:767-775(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 36-133
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