Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > TSHR(Gene name) > Human
  • Add your favorite
  • TSHR (Gene name),
  • Thyrotropin receptor (Protein name ),  TSHR_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    TSHR(LGR3);
    Protein name:
    Thyrotropin receptor;
    Alternative:
    Thyroid-stimulating hormone receptor(TSH-R);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
    Function:
    Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    764
    Sequence:
    50:
    MRPADLLQLV | LLLDLPRDLG | GMGCSSPPCE | CHQEEDFRVT | CKDIQRIPSL | 
    100:
    PPSTQTLKLI | ETHLRTIPSH | AFSNLPNISR | IYVSIDVTLQ | QLESHSFYNL | 
    150:
    SKVTHIEIRN | TRNLTYIDPD | ALKELPLLKF | LGIFNTGLKM | FPDLTKVYST | 
    200:
    DIFFILEITD | NPYMTSIPVN | AFQGLCNETL | TLKLYNNGFT | SVQGYAFNGT | 
    250:
    KLDAVYLNKN | KYLTVIDKDA | FGGVYSGPSL | LDVSQTSVTA | LPSKGLEHLK | 
    300:
    ELIARNTWTL | KKLPLSLSFL | HLTRADLSYP | SHCCAFKNQK | KIRGILESLM | 
    350:
    CNESSMQSLR | QRKSVNALNS | PLHQEYEENL | GDSIVGYKEK | SKFQDTHNNA | 
    400:
    HYYVFFEEQE | DEIIGFGQEL | KNPQEETLQA | FDSHYDYTIC | GDSEDMVCTP | 
    450:
    KSDEFNPCED | IMGYKFLRIV | VWFVSLLALL | GNVFVLLILL | TSHYKLNVPR | 
    500:
    FLMCNLAFAD | FCMGMYLLLI | ASVDLYTHSE | YYNHAIDWQT | GPGCNTAGFF | 
    550:
    TVFASELSVY | TLTVITLERW | YAITFAMRLD | RKIRLRHACA | IMVGGWVCCF | 
    600:
    LLALLPLVGI | SSYAKVSICL | PMDTETPLAL | AYIVFVLTLN | IVAFVIVCCC | 
    650:
    YVKIYITVRN | PQYNPGDKDT | KIAKRMAVLI | FTDFICMAPI | SFYALSAILN | 
    700:
    KPLITVSNSK | ILLVLFYPLN | SCANPFLYAI | FTKAFQRDVF | ILLSKFGICK | 
    750:
    RQAQAYRGQR | VPPKNSTDIQ | VQKVTHDMRQ | GLHNMEDVYE | LIENSHLTPK | 
    764:
    KQGQISEEYM | QTVL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    MIM:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Thyrotropin receptor
    Cat.:
    E9855h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Thyrotropin receptor
    MSDS:
    Please sign in first.
    ELISA Kit for Human Thyrotropin receptor
    Cat.:
    E9855m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Thyrotropin receptor
    Cat.:
    E9855r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Thyrotropin receptor
    Cat.:
    E9855p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Thyrotropin receptor
    Cat.:
    E9855b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Thyrotropin receptor
    Cat.:
    U9855m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Thyrotropin receptor
    Cat.:
    U9855h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Thyrotropin receptor
    Cat.:
    U9855r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Thyrotropin receptor
    Cat.:
    U9855b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Thyrotropin receptor
    Cat.:
    U9855p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Thyrotropin receptor
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human Thyrotropin receptor
    Polyclonal Antibody for Human Thyrotropin receptor
    Polyclonal Antibody for Human Thyrotropin receptor
    Polyclonal Antibody for Human Thyrotropin receptor
    Cat.:
    P9855Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Thyrotropin receptor
    Polyclonal Antibody for Human Thyrotropin receptor
    Cat.:
    P9855Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Thyrotropin receptor
    Monoclonal Antibody for Human Thyrotropin receptor
    Monoclonal Antibody for Human Thyrotropin receptor
    Monoclonal Antibody for Human Thyrotropin receptor
    Monoclonal Antibody for Human Thyrotropin receptor
    Monoclonal Antibody for Human Thyrotropin receptor
    Protein for Human Thyrotropin receptor
    Protein for Human Thyrotropin receptor
    Protein for Human Thyrotropin receptor
    Protein for Human Thyrotropin receptor
    Protein for Human Thyrotropin receptor
    Protein for Human Thyrotropin receptor

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor."
      Nagayama Y. , Kaufman K.D. , Seto P. , Rapoport B.
      Biochem. Biophys. Res. Commun.165:1184-1190(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
    2. 2.
      "Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies."
      Libert F. , Lefort A. , Gerard C. , Parmentier M. , Perret J. , Ludgate M. , Dumont J.E. , Vassart G.
      Biochem. Biophys. Res. Commun.165:1250-1255(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG);TISSUE SPECIFICITY
      tissue: Thyroid.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG);VARIANT GLU-727
    4. 4.
      "Isolation of TSH and LH/CG receptor cDNAs from human thyroid: regulation by tissue specific splicing."
      Frazier A.L. , Robbins L.S. , Stork P.J. , Sprengel R. , Segaloff D.L. , Cone R.D.
      Mol. Endocrinol.4:1264-1276(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
      tissue: Thyroid.
    5. 5.
      "Cloning and sequencing of a 1.3 KB variant of human thyrotropin receptor mRNA lacking the transmembrane domain."
      Graves P.N. , Tomer Y. , Davies T.F.
      Biochem. Biophys. Res. Commun.187:1135-1143(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
    6. 6.
      "Molecular cloning and sequencing of an alternatively spliced form of the human thyrotropin receptor transcript."
      Takeshita A. , Nagayama Y. , Fujiyama K. , Yokoyama N. , Namba H. , Yamashita S. , Izumi M. , Nagataki S.
      Biochem. Biophys. Res. Commun.188:1214-1219(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
      tissue: Thyroid.
    7. 7.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Kopatz S.A. , Aronstam R.S. , Sharma S.V.
      Submitted (2003-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG)
      tissue: Thyroid.
    8. 8.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT GLU-727
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS SHORT AND 3)
      tissue: Ovarian adenocarcinoma.
    10. 10.
      "Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor."
      Cornelis S. , Uttenweiler-Joseph S. , Panneels V. , Vassart G. , Costagliola S.
      Biochemistry40:9860-9869(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 66-80; 113-123; 184-210 AND 294-310;GLYCOSYLATION AT ASN-77; ASN-113; ASN-198 AND ASN-302
    11. 11.
      "Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor."
      Nakabayashi K. , Matsumi H. , Bhalla A. , Bae J. , Mosselman S. , Hsu S.Y. , Hsueh A.J.W.
      J. Clin. Invest.109:1445-1452(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH GPA2/GPB5
    12. 12.
      "Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway."
      Lahuna O. , Quellari M. , Achard C. , Nola S. , Meduri G. , Navarro C. , Vitale N. , Borg J.-P. , Misrahi M.
      EMBO J.24:1364-1374(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SCRIB
    13. 13.
      "Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions."
      Jiang X. , Dreano M. , Buckler D.R. , Cheng S. , Ythier A. , Wu H. , Hendrickson W.A. , el Tayar N.
      Structure3:1341-1353(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 54-236
    14. 14.
      "Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody."
      Sanders J. , Chirgadze D.Y. , Sanders P. , Baker S. , Sullivan A. , Bhardwaja A. , Bolton J. , Reeve M. , Nakatake N. , Evans M. , Richards T. , Powell M. , Miguel R.N. , Blundell T.L. , Furmaniak J. , Smith B.R.
      Thyroid17:395-410(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.55 ANGSTROMS) OF 22-260 IN COMPLEX WITH ANTIBODY;GLYCOSYLATION AT ASN-77; ASN-99; ASN-113; ASN-177 AND ASN-198;N-TERMINAL DISULFIDE BOND
    15. 15.
      "Further studies of genetic susceptibility to Graves' disease in a Russian population."
      Chistiakov D.A. , Savost'anov K.V. , Turakulov R.I. , Petunina N. , Balabolkin M.I. , Nosikov V.V.
      Med. Sci. Monit.8:CR180-CR184(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ANALYSIS OF INVOLVEMENT OF VARIANT GLU-727 IN GRAVES DISEASE
    16. 16.
      "A germline single nucleotide polymorphism at the intracellular domain of the human thyrotropin receptor does not have a major effect on the development of Graves' disease."
      Ban Y. , Greenberg D.A. , Concepcion E.S. , Tomer Y.
      Thyroid12:1079-1083(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ANALYSIS OF INVOLVEMENT OF VARIANT GLU-727 IN GRAVES DISEASE
    17. 17.
      "Association of Graves' disease with intragenic polymorphism of the thyrotropin receptor gene in a cohort of Singapore patients of multi-ethnic origins."
      Ho S.-C. , Goh S.-S. , Khoo D.H.
      Thyroid13:523-528(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ANALYSIS OF INVOLVEMENT OF VARIANTS HIS-36; THR-52 AND GLU-727 IN GRAVES DISEASE
    18. 18.
      "The human thyrotropin receptor is highly mutable: a review of gain-of-function mutations."
      Farid N.R. , Kascur V. , Balazs C.
      Eur. J. Endocrinol.143:25-30(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
    19. 19.
      "A somatic point mutation in a putative ligand binding domain of the TSH receptor in a patient with autoimmune hyperthyroidism."
      Heldin N.-E. , Gustavsson B. , Westermark K. , Westermark B.
      J. Clin. Endocrinol. Metab.73:1374-1376(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIS-36
    20. 20.
      "Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas."
      Parma J. , Duprez L. , van Sande J. , Cochaux P. , Gervy C. , Mockel J. , Dumont J.E. , Vassart G.
      Nature365:649-651(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HYPERTHYROIDISM GLY-619 AND ILE-623
    21. 21.
      "A genomic point mutation in the extracellular domain of the thyrotropin receptor in patients with Graves' ophthalmopathy."
      Bahn R.S. , Dutton C.M. , Heufelder A.E. , Sarkar G.
      J. Clin. Endocrinol. Metab.78:256-260(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-52
    22. 22.
      "Novel mutations of thyrotropin receptor gene in thyroid hyperfunctioning adenomas. Rapid identification by fine needle aspiration biopsy."
      Porcellini A. , Ciullo I. , Laviola L. , Amabile G. , Fenzi G. , Avvedimento V.E.
      J. Clin. Endocrinol. Metab.79:657-661(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HYPERTHYROIDISM CYS-631; ILE-632; GLU-633 AND TYR-633
    23. 23.
      "Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid."
      Paschke R. , Tonacchera M. , van Sande J. , Parma J. , Vassart G.
      J. Clin. Endocrinol. Metab.79:1785-1789(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HYPERTHYROIDISM VAL-623 AND ILE-632
    24. 24.
      "Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism."
      Duprez L. , Parma J. , van Sande J. , Allgeier A. , Leclere J. , Schvartz C. , Delisle M.-J. , Decoulx M. , Orgiazzi J. , Dumont J.E. , Vassart G.
      Nat. Genet.7:396-401(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HTNA ALA-509 AND TYR-672
    25. 25.
      "Functional analysis of a variant of the thyrotropin receptor gene in a family with Graves' disease."
      Gustavsson B. , Eklof C. , Westermark K. , Westermark B. , Heldin N.-E.
      Mol. Cell. Endocrinol.111:167-173(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT HIS-36
    26. 26.
      "Congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene."
      Kopp P. , van Sande J. , Parma J. , Duprez L. , Gerber H. , Joss E. , Jameson J.L. , Dumont J.E. , Vassart G.
      N. Engl. J. Med.332:150-154(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA LEU-631
    27. 27.
      "Resistance to thyrotropin caused by mutations in the thyrotropin-receptor gene."
      Sunthornthepvarakul T. , Gottschalk M.E. , Hayashi Y. , Refetoff S.
      N. Engl. J. Med.332:155-160(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CHNG1 ALA-162 AND ASN-167;VARIANT THR-52
    28. 28.
      "Point mutations in the thyrotropin receptor in human thyroid tumors."
      Ohno M. , Endo T. , Ohta K. , Gunji K. , Onaya T.
      Thyroid5:97-100(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PAPILLARY CANCER ILE-197; GLU-219; ASP-715 AND MET-723;VARIANT GLU-727
    29. 29.
      "Normal function in vivo of a homozygotic polymorphism in the human thyrotropin receptor."
      Cuddihy R.M. , Bryant W.P. , Bahn R.S.
      Thyroid5:255-257(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-52
    30. 30.
      "Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia."
      Tonacchera M. , van Sande J. , Cetani F. , Swillens S. , Schvartz C. , Winiszewski P. , Portmann L. , Dumont J.E. , Vassart G. , Parma J.
      J. Clin. Endocrinol. Metab.81:547-554(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HTNA ARG-505; TYR-650 AND SER-670
    31. 31.
      "A neomutation of the thyroid-stimulating hormone receptor in a severe neonatal hyperthyroidism."
      de Roux N. , Polak M. , Couet J. , Leger J. , Czernichow P. , Milgrom E. , Misrahi M.
      J. Clin. Endocrinol. Metab.81:2023-2026(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA THR-453
    32. 32.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CHNG1 SER-41; ALA-162; TRP-390; ASN-410 AND LEU-525
    33. 33.
      "Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma."
      Russo D. , Tumino S. , Arturi F. , Vigneri P. , Grasso G. , Pontecorvi A. , Filetti S. , Belfiore A.
      J. Clin. Endocrinol. Metab.82:735-738(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT INSULAR CARCINOMA HIS-633
    34. 34.
      "Two novel mutations in the thyrotropin (TSH) receptor gene in a child with resistance to TSH."
      Clifton-Bligh R.J. , Gregory J.W. , Ludgate M. , John R. , Persani L. , Asteria C. , Beck-Peccoz P. , Chatterjee V.K.K.
      J. Clin. Endocrinol. Metab.82:1094-1100(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CHNG1 GLN-109
    35. 35.
      "Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas."
      Parma J. , Duprez L. , van Sande J. , Hermans J. , Rocmans P. , van Vliet G. , Costagliola S. , Rodien P. , Dumont J.E. , Vassart G.
      J. Clin. Endocrinol. Metab.82:2695-2701(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HYPERTHYROIDISM ASN-281; THR-281; THR-453; PHE-486; MET-486; THR-568; GLY-619; ILE-623; PHE-629; LEU-630; LEU-631; ILE-632; ALA-633; GLU-633; HIS-633; TYR-633 AND 658-ASN--ILE-661 DEL
    36. 36.
      "Mutations of the human thyrotropin receptor gene causing thyroid hypoplasia and persistent congenital hypothyroidism."
      Biebermann H. , Schoeneberg T. , Krude H. , Schultz G. , Gudermann T. , Grueters A.
      J. Clin. Endocrinol. Metab.82:3471-3480(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CHNG1 TRP-390
    37. 37.
      "Sporadic congenital hyperthyroidism due to a spontaneous germline mutation in the thyrotropin receptor gene."
      Holzapfel H.P. , Wonerow P. , von Petrykowski W. , Henschen M. , Scherbaum W.A. , Paschke R.
      J. Clin. Endocrinol. Metab.82:3879-3884(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA ASN-505
    38. 38.
      "Identification of a new thyrotropin receptor germline mutation (Leu629Phe) in a family with neonatal onset of autosomal dominant nonautoimmune hyperthyroidism."
      Fuhrer D. , Wonerow P. , Willgerodt H. , Paschke R.
      J. Clin. Endocrinol. Metab.82:4234-4238(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA PHE-629
    39. 39.
      "Familial congenital hypothyroidism due to inactivating mutation of the thyrotropin receptor causing profound hypoplasia of the thyroid gland."
      Abramowicz M.J. , Duprez L. , Parma J. , Vassart G. , Heinrichs C.
      J. Clin. Invest.99:3018-3024(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CHNG1 THR-553
    40. 40.
      "Congenital hyperthyroidism caused by a solitary toxic adenoma harboring a novel somatic mutation (serine281-->isoleucine) in the extracellular domain of the thyrotropin receptor."
      Kopp P. , Muirhead S. , Jourdain N. , Gu W.X. , Jameson J.L. , Rodd C.
      J. Clin. Invest.100:1634-1639(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HYPERTHYROIDISM ILE-281
    41. 41.
      "Congenital nonautoimmune hyperthyroidism in a nonidentical twin caused by a sporadic germline mutation in the thyrotropin receptor gene."
      Kopp P. , Jameson J.L. , Roe T.F.
      Thyroid7:765-770(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA ILE-632
    42. 42.
      "Severe congenital hyperthyroidism caused by a germ-line neo mutation in the extracellular portion of the thyrotropin receptor."
      Grueters A. , Schoeneberg T. , Biebermann H. , Krude H. , Krohn H.P. , Dralle H. , Gudermann T.
      J. Clin. Endocrinol. Metab.83:1431-1436(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA ASN-281;VARIANT HIS-528
    43. 43.
      "Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin."
      Rodien P. , Bremont C. , Raffin Sanson M.-L. , Parma J. , van Sande J. , Costagliola S. , Luton J.-P. , Vassart G. , Duprez L.
      N. Engl. J. Med.339:1823-1826(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTFG ARG-183
    44. 44.
      "A germline mutation of the thyrotropin receptor gene associated with thyrotoxicosis and mitral valve prolapse in a Chinese family."
      Khoo D.H.C. , Parma J. , Rajasoorya C. , Ho S.C. , Vassart G.
      J. Clin. Endocrinol. Metab.84:1459-1462(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA SER-639
    45. 45.
      "Germline polymorphism of codon 727 of human thyroid-stimulating hormone receptor is associated with toxic multinodular goiter."
      Gabriel E.M. , Bergert E.R. , Grant C.S. , van Heerden J.A. , Thompson G.B. , Morris J.C.
      J. Clin. Endocrinol. Metab.84:3328-3335(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MET-606; GLY-703; GLU-720 AND GLU-727
    46. 46.
      "A Val 677 activating mutation of the thyrotropin receptor in a Hurthle cell thyroid carcinoma associated with thyrotoxicosis."
      Russo D. , Wong M.G. , Costante G. , Chiefari E. , Treseler P.A. , Arturi F. , Filetti S. , Clark O.H.
      Thyroid9:13-17(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THYROID CARCINOMA VAL-677
    47. 47.
      "A novel thyrotropin receptor mutation in an infant with severe thyrotoxicosis."
      Esapa C.T. , Duprez L. , Ludgate M. , Mustafa M.S. , Kendall-Taylor P. , Vassart G. , Harris P.E.
      Thyroid9:1005-1010(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HYPERTHYROIDISM LEU-597
    48. 48.
      "A novel activating mutation in the thyrotropin receptor gene in an autonomously functioning thyroid nodule developed by a Japanese patient."
      Kosugi S. , Hai N. , Okamoto H. , Sugawa H. , Mori T.
      Eur. J. Endocrinol.143:471-477(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HYPERTHYROIDISM ARG-512;CHARACTERIZATION OF VARIANT HYPERTHYROIDISM ARG-512
    49. 49.
      "Analysis of the genetic variability of the 1st (CCC/ACC, P52T) and the 10th exons (bp 1012-1704) of the TSH receptor gene in Graves' disease."
      Kaczur V. , Takacs M. , Szalai C. , Falus A. , Nagy Z. , Berencsi G. , Balazs C.
      Eur. J. Immunogenet.27:17-23(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-52
    50. 50.
      "Congenital hypothyroidism with impaired thyroid response to thyrotropin (TSH) and absent circulating thyroglobulin: evidence for a new inactivating mutation of the TSH receptor gene."
      Tonacchera M. , Agretti P. , Pinchera A. , Rosellini V. , Perri A. , Collecchi P. , Vitti P. , Chiovato L.
      J. Clin. Endocrinol. Metab.85:1001-1008(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CHNG1 ILE-477
    51. 51.
      "Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter."
      Tonacchera M. , Agretti P. , Chiovato L. , Rosellini V. , Ceccarini G. , Perri A. , Viacava P. , Naccarato A.G. , Miccoli P. , Pinchera A. , Vitti P.
      J. Clin. Endocrinol. Metab.85:2270-2274(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HTNA ASN-281; MET-486; PHE-486; PHE-629; ALA-632; ILE-632; GLU-633 AND VAL-647
    52. 52.
      "Lack of association of nonautoimmune hyperfunctioning thyroid disorders and a germline polymorphism of codon 727 of the human thyrotropin receptor in a European Caucasian population."
      Muehlberg T. , Herrmann K. , Joba W. , Kirchberger M. , Heberling H.-J. , Heufelder A.E.
      J. Clin. Endocrinol. Metab.85:2640-2643(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLU-727
    53. 53.
      "A novel mutation in the thyrotropin (TSH) receptor gene causing loss of TSH binding but constitutive receptor activation in a family with resistance to TSH."
      Russo D. , Betterle C. , Arturi F. , Chiefari E. , Girelli M.E. , Filetti S.
      J. Clin. Endocrinol. Metab.85:4238-4242(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CHNG1 CYS-310
    54. 54.
      "Constitutively activating TSH-receptor mutations as a molecular cause of non-autoimmune hyperthyroidism in childhood."
      Biebermann H. , Schoeneberg T. , Krude H. , Gudermann T. , Grueters A.
      Langenbecks Arch. Surg.385:390-392(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HTNA ASN-281; SER-431 AND ILE-632
    55. 55.
      "Sporadic nonautoimmune congenital hyperthyroidism due to a strong activating mutation of the thyrotropin receptor gene."
      Tonacchera M. , Agretti P. , Rosellini V. , Ceccarini G. , Perri A. , Zampolli M. , Longhi R. , Larizza D. , Pinchera A. , Vitti P. , Chiovato L.
      Thyroid10:859-863(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA THR-568
    56. 56.
      "A Phe 486 thyrotropin receptor mutation in an autonomously functioning follicular carcinoma that was causing hyperthyroidism."
      Camacho P. , Gordon D. , Chiefari E. , Yong S. , DeJong S. , Pitale S. , Russo D. , Filetti S.
      Thyroid10:1009-1012(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FOLLICULAR CARCINOMA PHE-486
    57. 57.
      "Novel TSHR germline mutation (Met463Val) masquerading as Graves' disease in a large Welsh kindred with hyperthyroidism."
      Fuhrer D. , Warner J. , Sequeira M. , Paschke R. , Gregory J.W. , Ludgate M.
      Thyroid10:1035-1041(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA VAL-463
    58. 58.
      "A novel germline mutation in the TSH receptor gene causes non-autoimmune autosomal dominant hyperthyroidism."
      Alberti L. , Proverbio M.C. , Costagliola S. , Weber G. , Beck-Peccoz P. , Chiumello G. , Persani L.
      Eur. J. Endocrinol.145:249-254(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA PHE-597;CHARACTERIZATION OF VARIANT HTNA PHE-597
    59. 59.
      "The first activating TSH receptor mutation in transmembrane domain 1 identified in a family with nonautoimmune hyperthyroidism."
      Biebermann H. , Schoeneberg T. , Hess C. , Germak J. , Gudermann T. , Grueters A.
      J. Clin. Endocrinol. Metab.86:4429-4433(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA SER-431;CHARACTERIZATION OF VARIANT HTNA SER-431
    60. 60.
      "Detection of thyroid-stimulating hormone receptor and G(s)alpha mutations: in 75 toxic thyroid nodules by denaturing gradient gel electrophoresis."
      Truelzsch B. , Krohn K. , Wonerow P. , Chey S. , Holzapfel H.-P. , Ackermann F. , Fuehrer D. , Paschke R.
      J. Mol. Med.78:684-691(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTNS ASN-281; ILE-425; THR-453; PHE-486; ASN-505; ARG-512; GLN-512; THR-568; GLY-619; VAL-623; LEU-631; ALA-632; ILE-632; GLU-633; HIS-633; TYR-633; ALA-639 AND PHE-656;CHARACTERIZATION OF VARIANTS TTNS ILE-425 AND GLN-512
    61. 61.
      "Novel inactivating missense mutations in the thyrotropin receptor gene in Japanese children with resistance to thyrotropin."
      Nagashima T. , Murakami M. , Onigata K. , Morimura T. , Nagashima K. , Mori M. , Morikawa A.
      Thyroid11:551-559(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CHNG1 HIS-450 AND SER-498
    62. 62.
      "Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population."
      Vanvooren V. , Uchino S. , Duprez L. , Costa M.J. , Vandekerckhove J. , Parma J. , Vassart G. , Dumont J.E. , van Sande J. , Noguchi S.
      Eur. J. Endocrinol.147:287-291(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HYPERTHYROIDISM THR-453; MET-486; ARG-512 AND ALA-632
    63. 63.
      "Germline mutations of TSH receptor gene as cause of nonautoimmune subclinical hypothyroidism."
      Alberti L. , Proverbio M.C. , Costagliola S. , Romoli R. , Boldrighini B. , Vigone M.C. , Weber G. , Chiumello G. , Beck-Peccoz P. , Persani L.
      J. Clin. Endocrinol. Metab.87:2549-2555(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CHNG1 SER-41; ALA-162; PRO-467 AND ARG-600
    64. 64.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TOXIC THYROID ADENOMA ASN-593;VARIANT GLU-727;CHARACTERIZATION OF VARIANTS TOXIC THYROID ADENOMA ASN-593 AND ASN-593/GLU-727;CHARACTERIZATION OF VARIANT GLU-727
    65. 65.
      "Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects."
      Peeters R.P. , van Toor H. , Klootwijk W. , de Rijke Y.B. , Kuiper G.G.J.M. , Uitterlinden A.G. , Visser T.J.
      J. Clin. Endocrinol. Metab.88:2880-2888(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HIS-36; THR-52 AND GLU-727;ASSOCIATION WITH PLASMA TSH LEVEL
    66. 66.
      "TSH receptor and Gs(alpha) genetic analysis in children with Down's syndrome and subclinical hypothyroidism."
      Tonacchera M. , Perri A. , De Marco G. , Agretti P. , Montanelli L. , Banco M.E. , Corrias A. , Bellone J. , Tosi M.T. , Vitti P. , Martino E. , Pinchera A. , Chiovato L.
      J. Endocrinol. Invest.26:997-1000(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HIS-36 AND THR-52;RECEPTOR GENETIC ANALYSIS IN CHILDREN WITH DOWN'S SYNDROME
    67. 67.
      "Congenital hypothyroidism and apparent athyreosis with compound heterozygosity or compensated hypothyroidism with probable hemizygosity for inactivating mutations of the TSH receptor."
      Park S.-M. , Clifton-Bligh R.J. , Betts P. , Chatterjee V.K.K.
      Clin. Endocrinol. (Oxf.)60:220-227(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CHNG1 THR-553
    68. 68.
      "Premature birth and low birth weight associated with nonautoimmune hyperthyroidism due to an activating thyrotropin receptor gene mutation."
      Vaidya B. , Campbell V. , Tripp J.H. , Spyer G. , Hattersley A.T. , Ellard S.
      Clin. Endocrinol. (Oxf.)60:711-718(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HTNA ASN-505
    69. 69.
      "Low prevalence of thyrotropin receptor mutations in a large series of subjects with sporadic and familial nonautoimmune subclinical hypothyroidism."
      Tonacchera M. , Perri A. , De Marco G. , Agretti P. , Banco M.E. , Di Cosmo C. , Grasso L. , Vitti P. , Chiovato L. , Pinchera A.
      J. Clin. Endocrinol. Metab.89:5787-5793(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CHNG1 ALA-162 AND PRO-252;CHARACTERIZATION OF VARIANT CHNG1 PRO-252
    Product Feedback Wall
    Hot Genes
    Top Searches
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter